Cancer-epigenetics comes of age
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[1] G. Martin,et al. Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation , 1987, Cell.
[2] P. Jones,et al. DNA methylation errors and cancer. , 1996, Cancer research.
[3] G. Prendergast,et al. Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. , 1991, Science.
[4] Peter A. Jones,et al. The Mutational Burden of 5-Methylcytosine , 1996 .
[5] P. Pollock,et al. Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds , 1997, Oncogene.
[6] J. Herman,et al. Alterations in DNA methylation: a fundamental aspect of neoplasia. , 1998, Advances in cancer research.
[7] Colin A. Johnson,et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex , 1998, Nature.
[8] R. Beart,et al. Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. , 1995, Cancer research.
[9] S. Clark,et al. Sp1 binding is inhibited by mCpmCpG methylation , 1997 .
[10] P. Laird,et al. COBRA: a sensitive and quantitative DNA methylation assay. , 1997, Nucleic acids research.
[11] M. Skolnick,et al. A cell cycle regulator potentially involved in genesis of many tumor types. , 1994, Science.
[12] A. Bird,et al. MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin , 1997, Cell.
[13] P. Jones,et al. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). , 1997, Nucleic acids research.
[14] Rudolf Jaenisch,et al. Role for DNA methylation in genomic imprinting , 1993, Nature.
[15] Y. Hosoya,et al. Establishment of methylation-sensitive-representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[16] A. Razin,et al. DNA methylation and gene expression , 1991, Microbiological reviews.
[17] A. Riggs,et al. X chromosome inactivation and DNA methylation. , 1993, EXS.
[18] E. Selker,et al. DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa. , 1997, Genes & development.
[19] N. Hayward,et al. Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors. , 1997, Cancer research.
[20] J. Herman,et al. Association between CpG island methylation and microsatellite instability in colorectal cancer. , 1997, Cancer research.
[21] S N Thibodeau,et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. , 1998, Cancer research.
[22] C. Harris,et al. Mutational spectrum of the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. , 1994, Drug metabolism reviews.
[23] P. Jones,et al. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. , 1998, Cancer research.
[24] A. Bird. CpG-rich islands and the function of DNA methylation , 1986, Nature.
[25] J. Herman,et al. Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia. , 1998, Cancer research.
[26] K. Kinzler,et al. DNA methylation and genetic instability in colorectal cancer cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[27] D. Lubahn,et al. Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique. , 1997, Cancer research.
[28] M. Ehrlich,et al. Binding of AP-1/CREB proteins and of MDBP to contiguous sites downstream of the human TGF-beta 1 gene. , 1994, Biochimica et biophysica acta.
[29] H. Prydz,et al. A methylated CpG island 3' in the apolipoprotein-E gene does not repress its transcription. , 1993, Human molecular genetics.
[30] M. Frommer,et al. CpG islands in vertebrate genomes. , 1987, Journal of molecular biology.
[31] S. Baylin,et al. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[32] P. Jones,et al. The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines. , 1998, Cancer research.
[33] A. Feinberg,et al. The genetics of BWS associated tumors , 1999 .
[34] V. Kosma,et al. Hypermethylation of the APC (adenomatous Polyposis Coli) gene promoter region in human colorectal carcinoma , 1997, International journal of cancer.
[35] D. Barlow,et al. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. , 1993, Cell.
[36] H. Prydz,et al. CpG islands as gene markers in the human genome. , 1992, Genomics.
[37] V. Chapman,et al. Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation , 1990, Molecular and cellular biology.
[38] A. Bird,et al. High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines , 1990, Cell.
[39] A. Wolffe,et al. How does DNA methylation repress transcription? , 1997, Trends in genetics : TIG.
[40] E. Li,et al. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases , 1998, Nature Genetics.
[41] M. DePamphilis,et al. Identifying 5-methylcytosine and related modifications in DNA genomes. , 1998, Nucleic acids research.
[42] L. Kasturi,et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[43] M. L. Villa. Fundamental Aspect of Neoplasia , 1976 .
[44] R. Jaenisch,et al. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[45] T. Dryja,et al. Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. , 1991, American journal of human genetics.
[46] T. Dryja,et al. Hypermethylation in the retinoblastoma gene is associated with unilateral, sporadic retinoblastoma. , 1997, Cancer genetics and cytogenetics.
[47] R. Weinberg,et al. Suppression of intestinal neoplasia by DNA hypomethylation , 1995, Cell.
[48] T. Sakai,et al. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. , 1993, Oncogene.
[49] S. Baylin,et al. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon , 1994, Nature Genetics.
[50] T. Mukai,et al. A new imprinted gene cloned by a methylation-sensitive genome scanning method. , 1993, Nucleic acids research.
[51] T. Bestor,et al. Gene silencing: Methylation meets acetylation , 1998, Nature.
[52] S. Richard,et al. Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors. , 1997, American journal of human genetics.
[53] S. Clark,et al. Sp1 binding is inhibited by (m)Cp(m)CpG methylation. , 1997, Gene.
[54] G. Liang,et al. Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. , 1997, Cancer research.
[55] M. Newton,et al. Overcoming cellular senescence in human cancer pathogenesis. , 1998, Genes & development.
[56] C. Harris,et al. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. , 1998, Cancer research.
[57] M. Link,et al. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. , 1997, Cancer research.
[58] A. Riggs,et al. DNA methylation and gene function. , 1980, Science.
[59] M. Monk,et al. Methylation of CpG sites of two X–linked genes coincides with X–inactivation in the female mouse embryo but not in the germ line , 1992, Nature Genetics.
[60] L. E. McDonald,et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[61] C. Harris,et al. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. , 1994, Cancer research.
[62] J. Herman,et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[63] D. Barlow,et al. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal , 1993, Cell.
[64] A. Feinberg,et al. Reduced genomic 5-methylcytosine content in human colonic neoplasia. , 1988, Cancer research.
[65] P. Jones,et al. The DNA methylation paradox. , 1999, Trends in genetics : TIG.
[66] J. Strouboulis,et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription , 1998, Nature Genetics.
[67] S. Tapscott,et al. De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[68] E. Wagner,et al. Imprinted expression of the Igf2r gene depends on an intronic CpG island , 1997, Nature.
[69] J. Herman,et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[70] A. Razin,et al. Gene methylation patterns and expression. , 1993, EXS.
[71] W. Gerald,et al. Epigenetic lesions at the H19 locus in Wilms' tumour patients , 1994, Nature Genetics.
[72] M. Ehrlich,et al. Effect of site-specific DNA methylation and mutagenesis on recognition by methylated DNA-binding protein from human placenta. , 1986, Nucleic acids research.
[73] Harris Cc,et al. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. , 1998 .
[74] M. Szyf,et al. Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[75] J. Rossignol,et al. Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.