Jesse Efrem Edwards, MD

DR JESSE E. EDWARDS HAS BECOME A LEGEND during his own lifetime. Not only because of his pioneering achievements as a cardiovascular pathologist, but also because of his unrivalled didactic skills, his unselfish attitude, and his warm personality. If there is such a thing as a "Hall of Fame" for pediatric cardiology, Dr Edwards certainly has to be among those inducted within it. I consider myself extremely privileged that I was allotted a fellowship with Dr Edwards from September 1969 through 1970, awarded by the (since long gone) Netherlands Organization for Pure Scientific Research. This time, spent together with my wife, will not easily be forgotten. When I first developed an interest in cardiovascular diseases, thinking at that time that I was to become a surgeon, it was impossible to read the literature without coming across the works of Dr Edwards. He was a pioneer in the pathologic aspects of both congenital and acquired cardiovascular diseases, and had the colossal ability to put the pathologic findings in their appropriate clinical perspective. To appreciate how this came about, it is worthwhile to provide a brief background of Dr Edwards' upbringing.

[1]  M. Silver,et al.  Right ventricular dysplasia: morphological findings in 13 cases. , 1992, The Canadian journal of cardiology.

[2]  J. Moller,et al.  Cardiac malformations in relatives of children with truncus arteriosus or interruption of the aortic arch. , 1988, The American journal of cardiology.

[3]  J. Edwards,et al.  Aortico-left ventricular tunnel and aortic insufficiency. , 1988, The Annals of thoracic surgery.

[4]  W. Edwards,et al.  Coexistent pulmonary and portal hypertension: morphologic and clinical features. , 1987, Journal of the American College of Cardiology.

[5]  J. Moller,et al.  Accessory tissue of the tricuspid valve protruding into the left ventricle through a septal defect. , 1986, Archives of pathology & laboratory medicine.

[6]  J. Lock,et al.  Morphologic changes in the pulmonary arteries after percutaneous balloon angioplasty for pulmonary arterial stenosis. , 1985, Circulation.

[7]  W. Edwards,et al.  Aortic origin of conus coronary artery. Evidence of postnatal coronary development. , 1981, British heart journal.

[8]  J. Edwards,et al.  Anatomic identification of so-called absent pulmonary artery. , 1978, Circulation.

[9]  A M Rudolph,et al.  Cardiac Malpositions: An Overview Based on Study of Sixty-five Necropsy Specimens , 1977, Circulation.

[10]  J. Moller,et al.  Clinical pathologic conference. , 1968, American heart journal.

[11]  J. Edwards,et al.  Anatomic causes of pulmonary stenosis in complete transposition. , 1976, Circulation.

[12]  W. Neal,et al.  Congenital left ventricular diverticulum. Part of a syndrome of cardiac anomalies and midline defects. , 1976, Minnesota medicine.

[13]  D. G. Ritter,et al.  Double outlet right ventricle: Anatomic and angiographic correlations , 1976 .

[14]  J. Edwards,et al.  Right Aortic Arch: Types and Associated Cardiac Anomalies , 1974, Circulation.

[15]  J. Moller,et al.  Double inlet left ventricle. Straddling tricuspid valve. , 1974, British heart journal.

[16]  J. Edwards,et al.  Tricuspid atresia. A re-evaluation and classification. , 1974, The Journal of thoracic and cardiovascular surgery.

[17]  J. Moller,et al.  Common (Single) Ventricle with Normally Related Great Vessels , 1974, Circulation.

[18]  A. Rose,et al.  Communication between coronary sinus and left atrium. , 1974, British heart journal.

[19]  A. Castañeda,et al.  The "goose neck" of the endocardial cushion defect: anatomic basis. , 1974, Chest.

[20]  J. Edwards,et al.  Communication of Mitral Valve with Both Ventricles Associated with Double Outlet Right Ventricle , 1973, Circulation.

[21]  J. Edwards,et al.  Absence of Anatomic Origin from Heart of Pulmonary Arterial Supply , 1973, Circulation.

[22]  J. Edwards,et al.  Valvular competent patent foramen ovale in adults. , 1972, Minnesota medicine.

[23]  A. Becker,et al.  Pathology of the semilunar valve in persistent truncus arteriosus. , 1971, The Journal of thoracic and cardiovascular surgery.

[24]  A. Becker,et al.  Pathologic spectrum of dysplasia of the tricuspid valve. Features in common with Ebstein's malformation. , 1971, Archives of pathology.

[25]  A. Becker,et al.  Malposition of pulmonary arteries (crossed pulmonary arteries) in persistent truncus arteriosus. , 1970, The American journal of roentgenology, radium therapy, and nuclear medicine.

[26]  A. Becker,et al.  Anomalies Associated with Coarctation of Aorta Particular Reference to Infancy , 1970, Circulation.

[27]  J. Moller,et al.  Congenital Pulmonary Stenosis Resulting from Dysplasia of Valve , 1969, Circulation.

[28]  J. Edwards,et al.  Anatomic factors causing respiratory distress in acyanotic congenital cardiac disease. Special reference to bronchial obstruction. , 1969, Pediatrics.

[29]  J. Edwards,et al.  Reference to Transposition, Dextrocardia and the Concept of Four Normal Hearts , 1968, Circulation.

[30]  J. Moller,et al.  Congenital Cardiac Disease Associated with Polysplenia: A Developmental Complex of Bilateral “Left‐Sidedness” , 1967, Circulation.

[31]  J. Moller,et al.  Atresia of the common pulmonary vein. Case report and differential diagnosis. , 1967, The American journal of roentgenology, radium therapy, and nuclear medicine.

[32]  J. Edwards,et al.  Anomalous Mitral Arcade: A Type of Congenital Mitral Insufficiency , 1967, Circulation.

[33]  R. S. Eliot,et al.  Symptomatic congenital aortic stenosis in the first year of life. , 1966, The Journal of pediatrics.

[34]  J. Moller,et al.  Anatomic Evidence for Spontaneous Closure of Ventricular Septal Defect , 1966, Circulation.

[35]  J. Edwards,et al.  Anomalous origins of pulmonary arteries from pulmonary frunk (“crossed pulmonary arteries”) , 1966 .

[36]  C. Lillehei,et al.  Congenital Anomalies Involving the Coronary Sinus , 1966, Circulation.

[37]  J. Edwards,et al.  Pulmonary atresia with left ventricular-right atrial communication: basis for circular shunt. , 1966, Thorax.

[38]  J. Edwards,et al.  Supravalvular aortic stenosis. , 1965, The Journal of thoracic and cardiovascular surgery.

[39]  K. Amplatz,et al.  Anomalous origin of the left pulmonary artery from the right pulmonary artery. Report of 2 cases and review of the literature. , 1965, The American journal of roentgenology, radium therapy, and nuclear medicine.

[40]  J. Moller,et al.  Interruption of aortic arch; anatomic patterns and associated cardiac malformations. , 1965, The American journal of roentgenology, radium therapy, and nuclear medicine.

[41]  J. Edwards,et al.  Aortic atresia and premature closure of foramen ovale. Myocardial sinusoids and coronary arteriovenous fistula serving as outflow channel. , 1965, American heart journal.

[42]  J. Edwards,et al.  Inverted Malformations in Corrected Transposition of the Great Vessels , 1965, Circulation.

[43]  S. Rahimtoola,et al.  ANOMALOUS CONNECTION OF PULMONARY VEINS TO RIGHT ATRIUM ASSOCIATED WITH ANOMALOUS INFERIOR VENA CAVA, SITUS INVERSUS AND MULTIPLE SPLEENS: A DEVELOPMENTAL COMPLEX. , 1965, Mayo Clinic proceedings.

[44]  J. Moller,et al.  Endocardial Fibroelastosis: A Clinical and Anatomic Study of 47 Patients with Emphasis on Its Relationship to Mitral Insufficiency , 1964, Circulation.

[45]  J. Moller,et al.  Anomalous Origin of the Left Coronary Artery from the Pulmonary Trunk with Special Reference to the Occurrence of Mitral Insufficiency , 1964, Circulation.

[46]  J. Edwards,et al.  SYNDROME OF CONGENITAL CARDIAC DISEASE WITH ASPLENIA. DISTINCTION FROM OTHER FORMS OF CONGENITAL CYANOTIC CARDIAC DISEASE. , 1964, The American journal of cardiology.

[47]  J. Edwards.  Editorial: The Direction of Blood Flow in Coronary Arteries Arising from the Pulmonary Trunk , 1964, Circulation.

[48]  J. Edwards,et al.  Anatomy of the Atrioventricular Conduction System in Ventricular Septal Defect , 1963, Circulation.

[49]  C. Lillehei,et al.  The developmental complex of "parachute mitral valve," supravalvular ring of left atrium, subaortic stenosis, and coarctation of aorta. , 1963, The American journal of cardiology.

[50]  J. Edwards,et al.  Editorial: On the Etiology of Calcific Aortic Stenosis , 1962 .

[51]  K. Amplatz,et al.  Congenital Stenosis of Individual Pulmonary Veins , 1962, Circulation.

[52]  J. Edwards,et al.  The Symmetrical Liver as a Roentgen Sign of Asplenia , 1962, Circulation.

[53]  J. Edwards,et al.  ORIGIN OF BOTH GREAT VESSELS FROM THE RIGHT VENTRICLE WITHOUT PULMONARY STENOSIS* , 1961, British heart journal.

[54]  A. Davignon,et al.  Congenital pulmonary atresia with intact ventricular septum. Clinicopathologic correlation of two anatomic types. , 1961, American heart journal.

[55]  R. Varco,et al.  Total anomalous pulmonary venous connection to the portal venous system: a cause of pulmonary venous obstruction. , 1961, The American journal of roentgenology, radium therapy, and nuclear medicine.

[56]  J. Edwards,et al.  The Pulmonary Arterial Tree in Ventricular Septal Defect: A Quantitative Study of Anatomic Features in Fetuses, Infants, and Children , 1961, Circulation.

[57]  J. Edwards,et al.  Editorial: The Congenital Bicuspid Aortic Valve , 1961 .

[58]  J. Edwards,et al.  Origin of Both Great Vessels from the Right Ventricle: II. With Pulmonary Stenosis , 1961, Circulation.

[59]  J. Edwards,et al.  The congenital bicuspid aortic valve. , 1961, Circulation.

[60]  J. Edwards,et al.  Total anomalous pulmonary venous connection. , 1960, American heart journal.

[61]  Edwards Je.  Congenital stenosis of pulmonary veins. Pathologic and developmental considerations. , 1960 .

[62]  J. Edwards,et al.  The problem of mitral insufficiency caused by accessory chordae tendineae in persistent common atrioventricular canal. , 1960, Proceedings of the staff meetings. Mayo Clinic.

[63]  J. E. Edwards.  Congenital stenosis of pulmonary veins. Pathologic and developmental considerations. , 1960, Laboratory investigation; a journal of technical methods and pathology.

[64]  E. Wood,et al.  The structure of the pulmonary trunk at different ages and in cases of pulmonary hypertension and pulmonary stenosis. , 1959, The Journal of pathology and bacteriology.

[65]  J. Edwards,et al.  Relation between Structural Changes in the Small Pulmonary Arteries and the Immediate Reversibility of Pulmonary Hypertension Following Closure of Ventricular and Atrial Septal Defects , 1958, Circulation.

[66]  J. Denie,et al.  Supravalvular Aortic Stenosis , 1958, Circulation.

[67]  J. Edwards,et al.  The Pathology of Hypertensive Pulmonary Vascular Disease: A Description of Six Grades of Structural Changes in the Pulmonary Arteries with Special Reference to Congenital Cardiac Septal Defects , 1958, Circulation.

[68]  A. Johnson,et al.  Infradiaphragmatic Total Anomalous Pulmonary Venous Connection , 1958, Circulation.

[69]  J. Edwards,et al.  The Pathological Anatomy of Deficiencies between the Aortic Root and the Heart, including Aortic Sinus Aneurysms , 1957, Thorax.

[70]  J. Edwards,et al.  The Lewis A. Conner Memorial Lecture: Functional Pathology of the Pulmonary Vascular Tree in Congenital Cardiac Disease , 1957 .

[71]  J. Edwards,et al.  Surgical correction of ventricular septal defect: anatomic and technical considerations. , 1957, The Journal of thoracic surgery.

[72]  W. N. Tauxe,et al.  A complex of congenital cardiac anomalies: ventricular septal defect, biventricular origin of the pulmonary trunk, and subaortic stenosis. , 1955, American heart journal.

[73]  C. E. Gilmore,et al.  Bilateral ductus arteriosus representing persistence of each sixth aortic arch; report of a case in which there were associated isolated dextrocardia and ventricular septal defects. , 1953, A.M.A. archives of pathology.

[74]  Edwards Je.  Malformations of the aortic arch system manifested as vascular rings. , 1953 .

[75]  J. E. Edwards.  Malformations of the aortic arch system manifested as vascular rings. , 1953, Laboratory investigation; a journal of technical methods and pathology.

[76]  C. Rossi,et al.  [Right aortic arch]. , 1952, Prensa medica argentina.

[77]  W. H. Civin,et al.  The postnatal structural changes in the intrapulmonary arteries and arterioles. , 1951, A.M.A. archives of pathology.

[78]  W. H. Civin,et al.  Pathology of the Pulmonary Vascular Tree: I. A Comparison of the Intrapulmonary Arteries in the Eisenmenger Complex and in Stenosis of Ostium Infundibuli Associated with Biventricular Origin of the Aorta , 1950, Circulation.

[79]  J. Edwards,et al.  Persistent Truncus Arteriosus: A Classification According to Anatomic Types , 1949 .

[80]  J. Edwards,et al.  Congenital Tricuspid Atresia: A Classification , 1949 .

[81]  J. Edwards,et al.  Incomplete division of the atrioventricular canal with patent interatrial foramen primum (persistent common atrioventricular ostium) , 1948 .

[82]  J. Edwards.  Retro-esophageal segment of the left aortic arch, right ligamentum arteriosum and right descending aorta causing a congenital vascular ring about the trachea and esophaguw. , 1948, Proceedings of the staff meetings. Mayo Clinic.

[83]  J. Edwards,et al.  Anomalies of the derivatives of the aortic arch system. , 1948, The Medical clinics of North America.

[84]  J. Edwards,et al.  Incomplete division of the atrioventricular canal with patent inter-atrial foramen primum, persistent common atrioventricular ostium; report of five cases and review of the literature. , 1948, American heart journal.

[85]  J. Edwards.  Vascular rings related to anomalies of the aortic arches. , 1948, Modern concepts of cardiovascular disease.

[86]  E. M. Hall.  The etiology of calcific aortic stenosis. , 1948, Annals of western medicine and surgery.

[87]  J. Edwards,et al.  The collateral circulation in coarctation of the aorta. , 1948, Proceedings of the staff meetings. Mayo Clinic.

[88]  J. Edwards,et al.  Pathologic considerations of coarctation of the aorta. , 1948, Proceedings of the staff meetings. Mayo Clinic.