A statistical software procedure for exact parametric and nonparametric likelihood-ratio tests for two-sample comparisons

ABSTRACT Two-sample comparisons belonging to basic class of statistical inference are extensively applied in practice. There is a rich statistical literature regarding different parametric methods to address these problems. In this context, most of the powerful techniques are assumed to be based on normally distributed populations. In practice, the alternative distributions of compared samples are commonly unknown. In this case, one can propose a combined test based on the following decision rules: (a) the likelihood-ratio test (LRT) for equality of two normal populations and (b) the Shapiro–Wilk (S-W) test for normality. The rules (a) and (b) can be merged by, e.g., using the Bonferroni correction technique to offer the correct comparison of the samples distribution. Alternatively, we propose the exact density-based empirical likelihood (DBEL) ratio test. We develop the tsc package as the first R package available to perform the two-sample comparisons using the exact test procedures: the LRT; the LRT combined with the S-W test; as well as the newly developed DBEL ratio test. We demonstrate Monte Carlo (MC) results and a real data example to show an efficiency and excellent applicability of the developed procedure.

[1]  Albert Vexler,et al.  An extensive power evaluation of a novel two-sample density-based empirical likelihood ratio test for paired data with an application to a treatment study of attention-deficit/hyperactivity disorder and severe mood dysregulation , 2013 .

[2]  Xiaotong Shen,et al.  Empirical Likelihood , 2002 .

[3]  Young Min Kim,et al.  Computing Critical Values of Exact Tests by Incorporating Monte Carlo Simulations Combined with Statistical Tables , 2014, Scandinavian journal of statistics, theory and applications.

[4]  Albert Vexler,et al.  dbEmpLikeGOF: An R Package for Nonparametric Likelihood Ratio Tests for Goodness-of-Fit and Two-Sample Comparisons Based on Sample Entropy , 2013 .

[5]  E F Schisterman,et al.  TBARS and Cardiovascular Disease in a Population-Based Sample , 2001, Journal of cardiovascular risk.

[6]  P. Sham,et al.  A note on the calculation of empirical P values from Monte Carlo procedures. , 2002, American journal of human genetics.

[7]  S. P. Wright,et al.  Adjusted P-values for simultaneous inference , 1992 .

[8]  Xinzhong Xu,et al.  The Exact Likelihood Ratio Test for Equality of Two Normal Populations , 2012 .

[9]  Stephen E. Fienberg,et al.  Testing Statistical Hypotheses , 2005 .

[10]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[11]  Alan D Hutson,et al.  Density-Based Empirical Likelihood Procedures for Testing Symmetry of Data Distributions and K-Sample Comparisons , 2014, The Stata journal.

[12]  Albert Vexler,et al.  Empirical likelihood ratios applied to goodness-of-fit tests based on sample entropy , 2010, Comput. Stat. Data Anal..

[13]  Albert Vexler,et al.  Density-Based Empirical Likelihood Ratio Change Point Detection Policies , 2010, Commun. Stat. Simul. Comput..

[14]  Albert Vexler,et al.  Two‐sample density‐based empirical likelihood ratio tests based on paired data, with application to a treatment study of attention‐deficit/hyperactivity disorder and severe mood dysregulation , 2012, Statistics in medicine.

[15]  E F Schisterman,et al.  Minimal and best linear combination of oxidative stress and antioxidant biomarkers to discriminate cardiovascular disease. , 2002, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[16]  N. Balakrishnan Methods and Applications of Statistics in Clinical Trials: Planning, Analysis, and Inferential Methods , 2014 .

[17]  Jianqing Fan,et al.  Local maximum likelihood estimation and inference , 1998 .

[18]  Albert Vexler,et al.  A two-sample empirical likelihood ratio test based on samples entropy , 2011, Stat. Comput..

[19]  N. Lazar Bayesian empirical likelihood , 2003 .

[20]  Albert Vexler,et al.  Two‐sample density‐based empirical likelihood tests for incomplete data in application to a pneumonia study , 2011, Biometrical journal. Biometrische Zeitschrift.