An alternative approach to understanding the pathophysiological mechanisms of chronic heart failure.

[1]  D. MacIver A new method for quantification of left ventricular systolic function using a corrected ejection fraction. , 2011, European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.

[2]  Douglas P. Zipes,et al.  Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 2-Volume Set, 10th Edition , 2011 .

[3]  A. Coats,et al.  Ethics in the authorship and publishing of scientific articles , 2010 .

[4]  H. Brunner-La Rocca,et al.  Hemodynamic basis of exercise limitation in patients with heart failure and normal ejection fraction. , 2010, Journal of the American College of Cardiology.

[5]  W. Paulus Culprit Mechanism(s) for Exercise Intolerance in Heart Failure With Normal Ejection Fraction. , 2010, Journal of the American College of Cardiology.

[6]  Amir Lerman,et al.  Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction. , 2010, Journal of the American College of Cardiology.

[7]  R. Nishimura,et al.  Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction , 2010, Circulation. Heart failure.

[8]  G. Buckberg,et al.  Cardiac remodelling and myocardial recovery: lost in translation? , 2010, European journal of heart failure.

[9]  B. Yan,et al.  Resting global and regional left ventricular contractility in patients with heart failure and normal ejection fraction: insights from speckle-tracking echocardiography , 2010, Heart.

[10]  D. MacIver Is remodeling the dominant compensatory mechanism in both chronic heart failure with preserved and reduced left ventricular ejection fraction? , 2010, Basic Research in Cardiology.

[11]  P. Ponikowski,et al.  Ferric carboxymaltose in patients with heart failure and iron deficiency. , 2009, The New England journal of medicine.

[12]  Rebekah A. Weaver,et al.  Impaired Heart Rate Recovery and Chronotropic Incompetence in Patients With Heart Failure With Preserved Ejection Fraction , 2009, Circulation. Heart failure.

[13]  Jeroen J. Bax,et al.  Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement. , 2009, European heart journal.

[14]  K. Matre,et al.  Myocardial deformation in aortic valve stenosis: relation to left ventricular geometry , 2009, Heart.

[15]  D. MacIver Surgical ventricular reconstruction. , 2009, The New England journal of medicine.

[16]  A. Henning,et al.  Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency. , 2009, Journal of the American College of Cardiology.

[17]  Yu Ting Tan,et al.  The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. , 2009, Journal of the American College of Cardiology.

[18]  J. Ribeiro,et al.  Respiratory muscle function and exercise intolerance in heart failure , 2009, Current heart failure reports.

[19]  Christopher M O'Connor,et al.  Coronary bypass surgery with or without surgical ventricular reconstruction. , 2009, The New England journal of medicine.

[20]  Anna Strömberg,et al.  Corrigendum to ‘ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008’ [Eur Heart J 2008;29:2388–2442 and Eur J Heart Fail 2008;10:933–989] , 2009 .

[21]  Scott D Flamm,et al.  Association between regional ventricular function and myocardial fibrosis in hypertrophic cardiomyopathy assessed by speckle tracking echocardiography and delayed hyperenhancement magnetic resonance imaging. , 2008, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[22]  D. Mancini,et al.  Comparison of blood volume characteristics in anemic patients with low versus preserved left ventricular ejection fractions. , 2008, The American journal of cardiology.

[23]  M. Zile,et al.  Transition From Chronic Compensated to Acute Decompensated Heart Failure: Pathophysiological Insights Obtained From Continuous Monitoring of Intracardiac Pressures , 2008, Circulation.

[24]  D. Atar,et al.  ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008 ‡ , 2008, European journal of heart failure.

[25]  W. Gaasch,et al.  Patterns of structural and functional remodeling of the left ventricle in chronic heart failure. , 2008, The American journal of cardiology.

[26]  Jianwen Wang,et al.  Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failure. , 2007, European heart journal.

[27]  K. Dickstein,et al.  How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. , 2007, European heart journal.

[28]  H. Krum,et al.  Heart Failure: A Practical Approach to Treatment , 2007 .

[29]  P. dos Santos,et al.  An ultrasound speckle tracking (two-dimensional strain) analysis of myocardial deformation in professional soccer players compared with healthy subjects and hypertrophic cardiomyopathy. , 2007, The American journal of cardiology.

[30]  D. MacIver,et al.  A novel mechanism of heart failure with normal ejection fraction , 2007, Heart.

[31]  D. Kass,et al.  Cardiac Structure and Ventricular–Vascular Function in Persons With Heart Failure and Preserved Ejection Fraction From Olmsted County, Minnesota , 2007, Circulation.

[32]  L. Fried,et al.  Ventricular structure and function in hypertensive participants with heart failure and a normal ejection fraction: the Cardiovascular Health Study. , 2007, Journal of the American College of Cardiology.

[33]  D. Kass,et al.  Impaired Chronotropic and Vasodilator Reserves Limit Exercise Capacity in Patients With Heart Failure and a Preserved Ejection Fraction , 2006, Circulation.

[34]  Serguei V. S. Pakhomov,et al.  Systolic and diastolic heart failure in the community. , 2006, JAMA.

[35]  A. Fraser,et al.  Systolic dysfunction in heart failure with a normal ejection fraction: echo-Doppler measurements. , 2006, Progress in cardiovascular diseases.

[36]  D. Ohad,et al.  Exhaustion of the Frank-Starling mechanism in conscious dogs with heart failure induced by chronic coronary microembolization. , 2006, Life sciences.

[37]  Leonardo L. Rodriguez,et al.  Reduced systolic performance by tissue Doppler in patients with preserved and abnormal ejection fraction: new insights in chronic heart failure. , 2006, International journal of cardiology.

[38]  K. Serri,et al.  Global and regional myocardial function quantification by two-dimensional strain: application in hypertrophic cardiomyopathy. , 2006, Journal of the American College of Cardiology.

[39]  Jeffrey C. Hill,et al.  Analysis of left ventricular systolic function using midwall mechanics in patients >60 years of age with hypertensive heart disease and heart failure. , 2005, The American journal of cardiology.

[40]  Robert H. Anderson,et al.  The anatomical arrangement of the myocardial cells making up the ventricular mass. , 2005, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[41]  E. Antman,et al.  ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult—Summary Article , 2005 .

[42]  A. Fraser,et al.  “Pure” diastolic dysfunction is associated with long‐axis systolic dysfunction. Implications for the diagnosis and classification of heart failure , 2005, European journal of heart failure.

[43]  G. Aurigemma,et al.  Left Ventricular Systolic Performance, Function, and Contractility in Patients With Diastolic Heart Failure , 2005, Circulation.

[44]  D. Burkhoff,et al.  Left heart failure with a normal ejection fraction: identification of different pathophysiologic mechanisms. , 2005, Journal of cardiac failure.

[45]  M. Zile,et al.  Diastolic heart failure: definitions and terminology. , 2005, Progress in cardiovascular diseases.

[46]  M. Quiñones Assessment of diastolic function. , 2005, Progress in cardiovascular diseases.

[47]  W. Gaasch,et al.  Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle. , 2004, The New England journal of medicine.

[48]  C Veyrat,et al.  Tissue Doppler, strain, and strain rate echocardiography for the assessment of left and right systolic ventricular function , 2003, Heart.

[49]  Oliver Turschner,et al.  Improvement of Cardiac Function During Enzyme Replacement Therapy in Patients With Fabry Disease: A Prospective Strain Rate Imaging Study , 2003, Circulation.

[50]  Philip Andrew,et al.  Diastolic heart failure demystified. , 2003, Chest.

[51]  R. Falk,et al.  Longitudinal Myocardial Function Assessed by Tissue Velocity, Strain, and Strain Rate Tissue Doppler Echocardiography in Patients With AL (Primary) Cardiac Amyloidosis , 2003, Circulation.

[52]  A. Coats,et al.  Congenital heart disease: the original heart failure syndrome. , 2003, European Heart Journal.

[53]  L. Zanolla,et al.  Skeletal muscle abnormalities in chronic heart failure patients: relation to exercise capacity and therapeutic implications. , 2003, Congestive heart failure.

[54]  D. Burkhoff,et al.  Heart failure with a normal ejection fraction: is it really a disorder of diastolic function? , 2003, Circulation.

[55]  D. Kass,et al.  Combined Ventricular Systolic and Arterial Stiffening in Patients With Heart Failure and Preserved Ejection Fraction: Implications for Systolic and Diastolic Reserve Limitations , 2003, Circulation.

[56]  W. Kindermann,et al.  Clinical study: cardiac magnetic resonance studiesAthlete’s heart: Right and left ventricular mass and function in male endurance athletes and untrained individuals determined by magnetic resonance imaging , 2002 .

[57]  A. Lange,et al.  The role of Doppler left ventricular filling indexes and Doppler tissue echocardiography in the assessment of cardiac involvement in hereditary hemochromatosis. , 2002, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[58]  D. Brutsaert,et al.  New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. , 2002, Circulation.

[59]  J. Carroll,et al.  Heart Failure With a Normal Ejection Fraction: Is Measurement of Diastolic Function Necessary to Make the Diagnosis of Diastolic Heart Failure? , 2001, Circulation.

[60]  B. Wandt,et al.  The mode of left ventricular pumping: is there an outer contour change in addition to the atrioventricular plane displacement? , 2001, Clinical physiology.

[61]  J. Kuijer,et al.  Quantification of regional contractile function after infarction: strain analysis superior to wall thickening analysis in discriminating infarct from remote myocardium. , 2001, Journal of the American College of Cardiology.

[62]  D. Mann Mechanisms and models in heart failure: A combinatorial approach. , 1999, Circulation.

[63]  J. Holmes,et al.  Frequency-dependence of myocardial energetics in failing human myocardium as quantified by a new method for the measurement of oxygen consumption in muscle strip preparations. , 1998, Journal of molecular and cellular cardiology.

[64]  E. Topol Textbook of Cardiovascular Medicine , 1997 .

[65]  A. Clark,et al.  The origin of symptoms in chronic heart failure , 1997, Heart.

[66]  T. Ino,et al.  Apoptosis as a possible cause of wall thinning in end-stage hypertrophic cardiomyopathy. , 1997, The American journal of cardiology.

[67]  M. Decramer,et al.  Peripheral and respiratory muscles in chronic heart failure. , 1996, The European respiratory journal.

[68]  J. Pepper,et al.  Histological abnormalities of muscle from limb, thorax and diaphragm in chronic heart failure. , 1996, European heart journal.

[69]  G. Aurigemma,et al.  Geometric changes allow normal ejection fraction despite depressed myocardial shortening in hypertensive left ventricular hypertrophy. , 1995, Journal of the American College of Cardiology.

[70]  J. Wilson,et al.  Dissociation between exertional symptoms and circulatory function in patients with heart failure. , 1995, Circulation.

[71]  P. Poole‐Wilson,et al.  Symptoms and quality of life in heart failure: the muscle hypothesis. , 1994, British heart journal.

[72]  E Erdmann,et al.  The failing human heart is unable to use the Frank-Starling mechanism. , 1994, Circulation research.

[73]  S. Vatner,et al.  Exhaustion of Frank-Starling mechanism in conscious dogs with heart failure. , 1993, The American journal of physiology.

[74]  D. Kass,et al.  Diminished Contractile Response to Increased Heart Rate in Intact Human Left Ventricular Hypertrophy Systolic Versus Diastolic Determinants , 1993, Circulation.

[75]  N. Alpert,et al.  Altered Myocardial Force‐Frequency Relation in Human Heart Failure , 1992, Circulation.

[76]  Pdod History of tuberculosis in Australia, New Zealand and Papua New Guinea , 1992, Annals of Internal Medicine.

[77]  W. Gaasch,et al.  Left Ventricular Midwall Mechanics in Systemic Arterial Hypertension Myocardial Function is Depressed in Pressure‐Overload Hypertrophy , 1991, Circulation.

[78]  D. Kitzman,et al.  Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: failure of the Frank-Starling mechanism. , 1991, Journal of the American College of Cardiology.

[79]  R. Kronmal,et al.  The Cardiovascular Health Study: design and rationale. , 1991, Annals of epidemiology.

[80]  K. Kessler Heart failure with normal systolic function. Update of prevalence, differential diagnosis, prognosis, and therapy. , 1988, Archives of internal medicine.

[81]  St. Cyres,et al.  Congestive cardiac failure: central role of the arterial blood pressure. , 1987, British heart journal.

[82]  R. Resnik,et al.  Effects of a Natural Volume Overload State (Pregnancy) on Left Ventricular Performance in Normal Human Subjects , 1978, Circulation.

[83]  A. Cohn DISEASE OF THE HEART. , 1945, Science.

[84]  S. Silver,et al.  Heart Failure , 1937, The New England journal of medicine.

[85]  H. Miyoshi,et al.  Concentric left ventricular hypertrophy brings deterioration of systolic longitudinal, circumferential, and radial myocardial deformation in hypertensive patients with preserved left ventricular pump function. , 2010, Journal of cardiology.

[86]  H. Trappe,et al.  Two-dimensional strain analysis of the global and regional myocardial function for the differentiation of pathologic and physiologic left ventricular hypertrophy: a study in athletes and in patients with hypertrophic cardiomyopathy , 2010, The International Journal of Cardiovascular Imaging.

[87]  D. MacIver Current controversies in heart failure with a preserved ejection fraction. , 2010, Future cardiology.

[88]  G. Jf [What is heart failure?]. , 1998, Archivos del Instituto de Cardiologia de Mexico.

[89]  M. Noble,et al.  The Interval-Force Relationship of the Heart: Bowditch Revisited , 1994 .

[90]  M W Bungo,et al.  Echocardiographic evaluation of space shuttle crewmembers. , 1987, Journal of applied physiology.

[91]  I. Starr RÔLE OF THE “STATIC BLOOD PRESSURE” IN ABNORMAL INCREMENTS OF VENOUS PRESSURE, ESPECIALLY IN HEART FAILURE. II. CLINICAL AND EXPERIMENTAL STUDIES , 1940 .