Notch signaling: Its essential roles in bone and craniofacial development

[1]  J. Zhao,et al.  ROCK‐TAZ signaling axis regulates mechanical tension‐induced osteogenic differentiation of rat cranial sagittal suture mesenchymal stem cells , 2020, Journal of cellular physiology.

[2]  T. He,et al.  "Imiquimod acts synergistically with BMP9 via the Notch pathway as an osteoinductive agent in vitro". , 2019, Plastic and reconstructive surgery.

[3]  A. Uezumi,et al.  Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle , 2019, eLife.

[4]  Chuifeng Fan,et al.  Hes3 Enhances the Malignant Phenotype of Lung Cancer through Upregulating Cyclin D1, Cyclin D3 and MMP7 Expression , 2019, International journal of medical sciences.

[5]  Di Wu,et al.  Defining a critical period in calvarial development for Hedgehog pathway antagonist-induced frontal bone dysplasia in mice , 2019, International Journal of Oral Science.

[6]  C. Lian,et al.  MiR-769 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Targeting HEY1 , 2018, Medical science monitor : international medical journal of experimental and clinical research.

[7]  P. Stanley,et al.  Multiple roles for O‐glycans in Notch signalling , 2018, FEBS letters.

[8]  Ying Zhao,et al.  MicroRNA-98 reduces amyloid β-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer’s disease mice , 2018, International journal of molecular medicine.

[9]  P. Nopoulos,et al.  FoxO6 regulates Hippo signaling and growth of the craniofacial complex , 2018, PLoS genetics.

[10]  R. Godbout,et al.  Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma , 2018, Neoplasia.

[11]  Libing Song,et al.  Overexpression of HES6 has prognostic value and promotes metastasis via the Wnt/β-catenin signaling pathway in colorectal cancer , 2018, Oncology reports.

[12]  Y. Bessho,et al.  Presomitic mesoderm-specific expression of the transcriptional repressor Hes7 is controlled by E-box, T-box, and Notch signaling pathways , 2018, The Journal of Biological Chemistry.

[13]  S. Winandy,et al.  A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells , 2018, Front. Immunol..

[14]  Chirag Nepal,et al.  Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain , 2018, Development.

[15]  M. Elowitz,et al.  Cis-activation in the Notch signaling pathway , 2018, bioRxiv.

[16]  S. Bray,et al.  Notch after cleavage. , 2018, Current opinion in cell biology.

[17]  H. Sang,et al.  Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination , 2018, PLoS biology.

[18]  Yinghong Zhou,et al.  The regulatory roles of Notch in osteocyte differentiation via the crosstalk with canonical Wnt pathways during the transition of osteoblasts to osteocytes. , 2018, Bone.

[19]  Ross Crawford,et al.  Notch expressed by osteocytes plays a critical role in mineralisation , 2018, Journal of Molecular Medicine.

[20]  R. Senos,et al.  Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects , 2017, npj Regenerative Medicine.

[21]  U. Lendahl,et al.  Notch Signaling in Development, Tissue Homeostasis, and Disease. , 2017, Physiological reviews.

[22]  T. He,et al.  Neural EGF-like protein 1 (NELL-1): Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine , 2017, Genes & diseases.

[23]  Jian Xu,et al.  BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice , 2017, Development.

[24]  N. Segil,et al.  Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear , 2017, Scientific Reports.

[25]  M. Krampera,et al.  Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog , 2017, Cancer biology & medicine.

[26]  Xiao-Jing Zhu,et al.  A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development , 2017, The Journal of Biological Chemistry.

[27]  J. Turnbull,et al.  Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis , 2017, Neuroreport.

[28]  F. Radtke,et al.  Notch as a tumour suppressor , 2017, Nature Reviews Cancer.

[29]  Ling Yu,et al.  Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling , 2017, European journal of pharmacology.

[30]  A. Quarshie,et al.  Leptin-Notch signaling axis is involved in pancreatic cancer progression , 2016, Oncotarget.

[31]  D. Fekete,et al.  Notch-Wnt-Bmp crosstalk regulates radial patterning in the mouse cochlea in a spatiotemporal manner , 2016, Development.

[32]  B. Sharma,et al.  Notch: A multi-functional integrating system of microenvironmental signals. , 2016, Developmental biology.

[33]  K. Stensløkken,et al.  Osteoblast Differentiation at a Glance , 2016, Medical science monitor basic research.

[34]  K. Sim,et al.  Development and Growth of the Normal Cranial Vault : An Embryologic Review , 2016, Journal of Korean Neurosurgical Society.

[35]  Shahida Moosa,et al.  Altered FGF signalling in congenital craniofacial and skeletal disorders. , 2016, Seminars in cell & developmental biology.

[36]  E. Canalis,et al.  Notch Signaling and the Skeleton. , 2016, Endocrine reviews.

[37]  Franz Oswald,et al.  The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways. , 2016, Biochimica et biophysica acta.

[38]  Y. Mishina,et al.  Common mechanisms in development and disease: BMP signaling in craniofacial development. , 2016, Cytokine & growth factor reviews.

[39]  A. Pitsillides,et al.  E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models , 2015, Journal of cellular physiology.

[40]  Maryam K. Mohammed,et al.  Stem cells, growth factors and scaffolds in craniofacial regenerative medicine , 2015, Genes & diseases.

[41]  J. Epstein,et al.  Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest , 2015, Development.

[42]  S. Twigg,et al.  New insights into craniofacial malformations. , 2015, Human molecular genetics.

[43]  L. Marchionni,et al.  HES6 promotes prostate cancer aggressiveness independently of Notch signalling , 2015, Journal of cellular and molecular medicine.

[44]  H. Clevers,et al.  Premigratory and migratory neural crest cells are multipotent in vivo. , 2015, Cell stem cell.

[45]  S. Gronthos,et al.  Novel basic helix-loop-helix transcription factor hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells. , 2015, Stem cells and development.

[46]  B. Osborne,et al.  Non-Canonical Notch Signaling in Cancer and Immunity , 2014, Front. Oncol..

[47]  Miguel Manzanares,et al.  Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. , 2014, Developmental cell.

[48]  T. Schilling,et al.  Wnt Signaling Interacts with Bmp and Edn1 to Regulate Dorsal-Ventral Patterning and Growth of the Craniofacial Skeleton , 2014, PLoS genetics.

[49]  J. Burdick,et al.  Jagged1 immobilization to an osteoconductive polymer activates the Notch signaling pathway and induces osteogenesis. , 2014, Journal of biomedical materials research. Part A.

[50]  S. A. Janjua,et al.  Adams-Oliver syndrome , 2020, Definitions.

[51]  M. Ibañes,et al.  Competition in Notch Signaling with Cis Enriches Cell Fate Decisions , 2014, PloS one.

[52]  A Gulino,et al.  Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia , 2014, Leukemia.

[53]  T. He,et al.  Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. , 2014, Current cancer drug targets.

[54]  Joshua T. Morgan,et al.  What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease. , 2013, Experimental eye research.

[55]  Hyun-Sook Kim,et al.  MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma. , 2013, Human pathology.

[56]  S. Artavanis-Tsakonas,et al.  Notch signaling at a glance , 2013, Journal of Cell Science.

[57]  Fanxin Long,et al.  Notch Signaling and Bone Remodeling , 2013, Current Osteoporosis Reports.

[58]  Jingjing Sun,et al.  Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2 , 2013, Development.

[59]  R. O’Keefe,et al.  Inhibition of the Wnt-β-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy. , 2013, Biochemical and biophysical research communications.

[60]  S. Yılmaz,et al.  The association of Alagille syndrome and craniosynostosis. , 2013, Pediatric neurology.

[61]  H. Akiyama,et al.  Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development , 2013, Proceedings of the National Academy of Sciences.

[62]  B. Lilly,et al.  Notch2 and Notch3 Function Together to Regulate Vascular Smooth Muscle Development , 2012, PloS one.

[63]  Ryoichiro Kageyama,et al.  A Mechanism for Gene-Environment Interaction in the Etiology of Congenital Scoliosis , 2012, Cell.

[64]  F. Sarkar,et al.  The Tyrosine Kinase c-Src Directly Mediates Growth Factor-Induced Notch-1 and Furin Interaction and Notch-1 Activation in Pancreatic Cancer Cells , 2012, PloS one.

[65]  M. Gessler,et al.  Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1 , 2012, PLoS genetics.

[66]  Jun Wang,et al.  Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development , 2012, Development.

[67]  E. Canalis,et al.  Notch Regulation of Bone Development and Remodeling and Related Skeletal Disorders , 2012, Calcified Tissue International.

[68]  D. Tuveson,et al.  Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice. , 2011, The Journal of clinical investigation.

[69]  K. Hankenson,et al.  Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation , 2011, Journal of cellular biochemistry.

[70]  Kazuyuki Aihara,et al.  Neural fate decisions mediated by trans-activation and cis-inhibition in Notch signaling , 2011, Bioinform..

[71]  R. Shivdasani,et al.  Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme , 2011, Development.

[72]  Shanchun Guo,et al.  Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer , 2011, PloS one.

[73]  R. Hinton,et al.  Cell fate mediators Notch and Twist in mouse mandibular condylar cartilage. , 2011, Archives of oral biology.

[74]  S. Ivy,et al.  Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways , 2011, Nature Reviews Clinical Oncology.

[75]  Wei Hsu,et al.  Gpr177/mouse Wntless is essential for Wnt‐mediated craniofacial and brain development , 2011, Developmental dynamics : an official publication of the American Association of Anatomists.

[76]  B. Merriman,et al.  Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling. , 2010, American journal of human genetics.

[77]  R. Hegele,et al.  Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling. , 2010, American journal of human genetics.

[78]  R. Maxson,et al.  Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells. , 2010, Developmental biology.

[79]  B. Dawson,et al.  Osteosclerosis owing to Notch gain of function is solely Rbpj‐dependent , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[80]  H. Jafar-Nejad,et al.  Role of glycans and glycosyltransferases in the regulation of Notch signaling. , 2010, Glycobiology.

[81]  Frank Stellabotte,et al.  Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face , 2010, Development.

[82]  Liza J. Raggatt,et al.  Cellular and Molecular Mechanisms of Bone Remodeling* , 2010, The Journal of Biological Chemistry.

[83]  T. Honjo,et al.  RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development , 2010, Development.

[84]  Bjarni V. Halldórsson,et al.  Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. , 2010, American journal of human genetics.

[85]  H. Sasaki,et al.  Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation , 2009, British Journal of Cancer.

[86]  Kenro Kusumi,et al.  Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis. , 2009, Developmental biology.

[87]  Raphael Kopan,et al.  The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism , 2009, Cell.

[88]  L. Donehower,et al.  Notch signaling contributes to the pathogenesis of human osteosarcomas. , 2009, Human molecular genetics.

[89]  T. Suda,et al.  Craniofacial malformation in R-spondin2 knockout mice. , 2009, Biochemical and biophysical research communications.

[90]  J. Eloy,et al.  Nasal, septal, and turbinate anatomy and embryology. , 2009, Otolaryngologic clinics of North America.

[91]  Jingjing Sun,et al.  EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis , 2009, Development.

[92]  A. Giordano,et al.  Leptin signaling in breast cancer: An overview , 2008, Journal of cellular biochemistry.

[93]  M. Lotz,et al.  Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site. , 2008, Arthritis and rheumatism.

[94]  A. Bigas,et al.  The Association of Notch2 and NF-κB Accelerates RANKL-Induced Osteoclastogenesis , 2008, Molecular and Cellular Biology.

[95]  N. Segil,et al.  Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode , 2008, Development.

[96]  D. Durant,et al.  Notch inhibits osteoblast differentiation and causes osteopenia. , 2008, Endocrinology.

[97]  Chin-Tong Ong,et al.  NOTCH1 Regulates Osteoclastogenesis Directly in Osteoclast Precursors and Indirectly via Osteoblast Lineage Cells* , 2008, Journal of Biological Chemistry.

[98]  Brendan H. Lee,et al.  Dimorphic effects of Notch signaling in bone homeostasis , 2008, Nature Medicine.

[99]  Tatsuya Kobayashi,et al.  Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation , 2008, Nature Medicine.

[100]  G. F. Judisch,et al.  Four Generations of Arteriohepatic Dysplasia , 2007, Hepatology.

[101]  D. Sgroi,et al.  Synergism between NF-κB1/p50 and Notch2 during the Development of Marginal Zone B Lymphocytes1 , 2007, The Journal of Immunology.

[102]  M. Katoh.  Networking of WNT, FGF, Notch, BMP, and Hedgehog Signaling Pathways during Carcinogenesis , 2007, Stem Cell Reviews.

[103]  K. Sakamoto,et al.  CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways. , 2007, Biochemical and biophysical research communications.

[104]  S. Bray.  Notch signalling: a simple pathway becomes complex , 2006, Nature Reviews Molecular Cell Biology.

[105]  I. Krantz,et al.  NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. , 2006, American journal of human genetics.

[106]  K. Lyons,et al.  Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. , 2006, Human molecular genetics.

[107]  E. Canalis,et al.  Notch 1 Overexpression Inhibits Osteoblastogenesis by Suppressing Wnt/β-Catenin but Not Bone Morphogenetic Protein Signaling* , 2006, Journal of Biological Chemistry.

[108]  B. Mccright,et al.  Generation of new Notch2 mutant alleles , 2006, Genesis.

[109]  J. Boulter,et al.  The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands , 2005, The Journal of cell biology.

[110]  T. Südhof,et al.  Nicastrin Functions as a γ-Secretase-Substrate Receptor , 2005, Cell.

[111]  E. Hay,et al.  The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[112]  E. Zackai,et al.  Molecular analysis of congenital scoliosis: a candidate gene approach , 2005, Human Genetics.

[113]  Ryoichiro Kageyama,et al.  Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation , 2004, Development.

[114]  Gavin Thurston,et al.  Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[115]  J. Aster,et al.  Notch Subunit Heterodimerization and Prevention of Ligand-Independent Proteolytic Activation Depend, Respectively, on a Novel Domain and the LNR Repeats , 2004, Molecular and Cellular Biology.

[116]  M. Šuša,et al.  Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. , 2004, The Journal of biological chemistry.

[117]  Manfred Gessler,et al.  The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. , 2004, Genes & development.

[118]  John A Latham,et al.  Osteocyte control of bone formation via sclerostin, a novel BMP antagonist , 2003, The EMBO journal.

[119]  U. Lendahl,et al.  Characterization of Notch3‐deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation , 2003, Genesis.

[120]  P. Hobar,et al.  Common craniofacial anomalies: facial clefts and encephaloceles. , 2003, Plastic and reconstructive surgery.

[121]  Oscar H. Ocaña,et al.  Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus , 2003, Development.

[122]  T. Gridley.  Notch signaling and inherited disease syndromes. , 2003, Human molecular genetics.

[123]  E. Carver,et al.  Craniosynostosis in Twist heterozygous mice: A model for Saethre‐Chotzen syndrome , 2002, The Anatomical record.

[124]  I. Krantz,et al.  Craniosynostosis in Alagille syndrome. , 2002, American journal of medical genetics.

[125]  C. Marcelle,et al.  Ectodermal Wnt Function as a Neural Crest Inducer , 2002, Science.

[126]  A. Chaventré,et al.  Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1. , 2002, American journal of human genetics.

[127]  C. Tabin,et al.  Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer , 2002, Genesis.

[128]  R. Beddington,et al.  Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. , 2002, Development.

[129]  K. Tezuka,et al.  Stimulation of Osteoblastic Cell Differentiation by Notch , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[130]  S. Jimenez,et al.  Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. , 2001, The Biochemical journal.

[131]  L. Miele,et al.  Human Notch-1 Inhibits NF-κB Activity in the Nucleus Through a Direct Interaction Involving a Novel Domain1 , 2001, The Journal of Immunology.

[132]  L A Opperman,et al.  Cranial sutures as intramembranous bone growth sites , 2000, Developmental dynamics : an official publication of the American Association of Anatomists.

[133]  R. Tuan,et al.  Cellular interactions and signaling in cartilage development. , 2000, Osteoarthritis and cartilage.

[134]  Y. Bessho,et al.  The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. , 2000, Development.

[135]  J. Sundberg,et al.  Notch signaling is essential for vascular morphogenesis in mice. , 2000, Genes & development.

[136]  F. Watt,et al.  Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters , 2000, Current Biology.

[137]  E. Lander,et al.  Mutations in the human Delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis , 2000, Nature Genetics.

[138]  C. Kahn,et al.  Selective interaction between leptin and insulin signaling pathways in a hepatic cell line. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[139]  M. Ferguson,et al.  Pathogenesis of cleft palate in TGF-beta3 knockout mice. , 1999, Development.

[140]  T. Price,et al.  Presence of leptin in breast cell lines and breast tumors. , 1999, Biochemical and biophysical research communications.

[141]  Céline Gélinas,et al.  Rel/NF‐κB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors , 1999, The EMBO journal.

[142]  G. Weinmaster,et al.  Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. , 1999, Human molecular genetics.

[143]  S. Artavanis-Tsakonas,et al.  Notch Signaling : Cell Fate Control and Signal Integration in Development , 1999 .

[144]  E. Robertson,et al.  Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. , 1999, Development.

[145]  M. W. Young,et al.  Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. , 1998, Genes & development.

[146]  A. Israël,et al.  The Notch1 receptor is cleaved constitutively by a furin-like convertase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[147]  B. Birren,et al.  The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries , 1998, Nature Genetics.

[148]  D. Lacey,et al.  Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.

[149]  G. Weinmaster,et al.  Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. , 1998, Genes & development.

[150]  F. Oswald,et al.  NF-κB2 Is a Putative Target Gene of Activated Notch-1 via RBP-Jκ , 1998, Molecular and Cellular Biology.

[151]  J. Flier,et al.  Identification of SOCS-3 as a potential mediator of central leptin resistance. , 1998, Molecular cell.

[152]  J. Flier,et al.  Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor* , 1997, The Journal of Biological Chemistry.

[153]  S. Artavanis-Tsakonas,et al.  Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane , 1997, Cell.

[154]  D. White,et al.  Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding* , 1997, The Journal of Biological Chemistry.

[155]  Colin C. Collins,et al.  Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1 , 1997, Nature Genetics.

[156]  M. H. Angelis,et al.  Maintenance of somite borders in mice requires the Delta homologue Dll1 , 1997, Nature.

[157]  I. Krantz,et al.  Alagille syndrome. , 1997, Journal of medical genetics.

[158]  Christel Brou,et al.  Signalling downstream of activated mammalian Notch , 1995, Nature.

[159]  E. Ricciardelli.  Embryology and anatomy of the cranial base. , 1995, Clinics in plastic surgery.

[160]  J. Rossant,et al.  Notch1 is required for the coordinate segmentation of somites. , 1995, Development.

[161]  V. McKusick,et al.  Spondylocostal dysplasia. A dominantly inherited form of short-trunked dwarfism. , 1968, The American journal of medicine.

[162]  J. G. Warbrick.  The early development of the nasal cavity and upper lip in the human embryo. , 1960, Journal of anatomy.

[163]  R. B. Stark.  THE PATHOGENESIS OF HARELIP AND CLEFT PALATE , 1954, Plastic and reconstructive surgery.

[164]  Thomas Hunt Morgan,et al.  The Theory of the Gene , 1917, The American Naturalist.

[165]  F. P. Mall,et al.  Manual of Human Embryology , 1911, The Indian Medical Gazette.

[166]  T. Bumgarner.  Pediatric And Adolescent Osteosarcoma , 2016 .

[167]  Jingjing Sun,et al.  The Development of the Calvarial Bones and Sutures and the Pathophysiology of Craniosynostosis. , 2015, Current topics in developmental biology.

[168]  B. Olsen,et al.  Bone development. , 2015, Bone.

[169]  M. Yavropoulou,et al.  The role of notch signaling in bone development and disease , 2014, Hormones.

[170]  T. Bellido.  Osteocyte-Driven Bone Remodeling , 2013, Calcified Tissue International.

[171]  R. Tubbs,et al.  The human calvaria: a review of embryology, anatomy, pathology, and molecular development , 2011, Child's Nervous System.

[172]  N. Bhagavan,et al.  Chapter 35 – Mineral Metabolism , 2011 .

[173]  G. Ottaviani,et al.  The epidemiology of osteosarcoma. , 2009, Cancer treatment and research.

[174]  Xiao-Fan Wang,et al.  Signaling cross-talk between TGF-β/BMP and other pathways , 2009, Cell Research.

[175]  A. Lindahl,et al.  Notch signaling in chondrogenesis. , 2009, International review of cell and molecular biology.

[176]  T. Golde,et al.  Off the beaten pathway: the complex cross talk between Notch and NF-κB , 2008, Laboratory Investigation.

[177]  N. Perkins,et al.  Integrating cell-signalling pathways with NF-κB and IKK function , 2007, Nature Reviews Molecular Cell Biology.

[178]  N. Perkins,et al.  Regulation of NF-kappaB function. , 2006, Biochemical Society symposium.

[179]  S. Iseki,et al.  Tissue origins and interactions in the mammalian skull vault. , 2002, Developmental biology.

[180]  M. Yanagisawa,et al.  Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. , 2000, Developmental biology.

[181]  B. Olsen,et al.  Bone development. , 2000, Annual review of cell and developmental biology.

[182]  F. Oswald,et al.  NF- k B2 Is a Putative Target Gene of Activated Notch-1 via RBP-J k , 1998 .

[183]  E. Green,et al.  Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome , 1997, Nature Genetics.

[184]  Jingjing Sun,et al.  Foxc 1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx 2 , 2022 .