Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose

BackgroundTo evaluate a reduced range CT protocol in patients with suspected acute appendicitis as compared to standard abdominal CT regarding diagnostic performance, effective radiation dose and organ doses.MethodsIn this study, we retrospectively included 90 patients (43 female, mean age 56.7 ± 17 years) with suspected acute appendicitis who underwent CT of abdomen and pelvis. From those CTs, we reconstructed images with a reduced scan range from L1 to the the pubic symphysis. Full range and reduced range datasets were assessed by two radiologists for i) coverage of the Appendix, ii) presence/absence of appendicitis and iii) presence of differential diagnoses. Furthermore, effective radiation doses as well as organ doses were calculated using a commercially available dose management platform (Radimetrics, Bayer HealthCare).ResultsThe Appendix was covered by the reduced range CT in all cases. In 66 patients CT confirmed the presence of appendicitis. In 14 patients, other relevant differential diagnoses were identified by CT, whereas in 10 patients no relevant findings were detected. Both readers identified all patients with appendicitis on both full and reduced range CT.For reduced range CT, total effective dose was 39% lower than for full range CT (reduced range: 4.5 [1.9–11.2] vs. full range: 7.4 [3.3–18.8] mSv; p ≤ 0.001). Notably, a remarkable reduction of organ dose in the female breasts by 97% (0.1 [0.1–0.6] vs. 3.8 [0.5–18.8] mSv; p ≤ 0.001) and in the testicles in males by 81% (3.4 [0.7–32.7] vs. 17.6 [5.4–52.9] mSv; p ≤ 0.001) was observed for reduced range CT compared to full range CT.ConclusionsIn patients with suspected acute appendicitis, reduced range abdominopelvic CT results in a comparable diagnostic performance with a remarkable reduction of total effective radiation dose and organ doses (especially breast dose in female and testicle dose in male patients) as compared to full range CT.

[1]  Konstantin Nikolaou,et al.  Effect of reduced z-axis scan coverage on diagnostic performance and radiation dose of neck computed tomography in patients with suspected cervical abscess , 2017, PloS one.

[2]  Matthew Taecker,et al.  Low-dose Abdominal CT for Evaluating Suspected Appendicitis , 2012 .

[3]  R. Lamba,et al.  Accuracy and Radiation Dose Reduction of Limited-Range CT in the Evaluation of Acute Appendicitis in Pediatric Patients. , 2017, AJR. American journal of roentgenology.

[4]  V. Lai,et al.  Diagnostic power of various computed tomography signs in diagnosing acute appendicitis. , 2012, Clinical imaging.

[5]  Jong Hyo Kim,et al.  Impact of Radiation Dose Reduction in Abdominal Computed Tomography on Diagnostic Accuracy and Diagnostic Performance in Patients with Suspected Appendicitis: An Intraindividual Comparison. , 2017, Academic radiology.

[6]  Yu-hui Huang,et al.  Abdominal-pelvic scanning parameters revisited: a case for Z-axis reduction in patients with clinical suspicion for acute appendicitis , 2017, Emergency Radiology.

[7]  J. Richardson,et al.  Acute appendicitis--not just for the young. , 2011, American journal of surgery.

[8]  K. Lee,et al.  Acute appendicitis in young adults: low- versus standard-radiation-dose contrast-enhanced abdominal CT for diagnosis. , 2011, Radiology.

[9]  P. Pickhardt,et al.  Alternative diagnoses to suspected appendicitis at CT. , 2012, Radiology.

[10]  S. Goldberg,et al.  Right lower quadrant pain and suspected appendicitis: nonfocused appendiceal CT--review of 100 cases. , 2000, Radiology.

[11]  Chang-Woo Ryu,et al.  Comparison of Low- and Standard-Dose CT for the Diagnosis of Acute Appendicitis: A Meta-Analysis. , 2017, AJR. American journal of roentgenology.

[12]  J. Yamamura,et al.  Imaging of Appendicitis in Adults , 2014, Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.

[13]  K. Nikolaou,et al.  Evaluation of reduced-dose CT for acute non-traumatic abdominal pain: evaluation of diagnostic accuracy in comparison to standard-dose CT , 2018, Acta radiologica.

[14]  R. Lamba,et al.  Accuracy and radiation dose reduction of a limited abdominopelvic CT in the diagnosis of acute appendicitis , 2015, Abdominal Imaging.

[15]  H. Moshonov,et al.  CT following US for possible appendicitis: anatomic coverage , 2016, European Radiology.

[16]  P. Gevenois,et al.  Optimised z-axis coverage at multidetector-row CT in adults suspected of acute appendicitis. , 2013, The British journal of radiology.