Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14+ monocytes in frail older adults

[1]  G. Wang,et al.  T‐Lymphocytes Expressing CC Chemokine Receptor‐5 Are Increased in Frail Older Adults , 2008, Journal of the American Geriatrics Society.

[2]  L. Fried,et al.  Inflammation and Frailty in Older Women , 2007, Journal of the American Geriatrics Society.

[3]  G. Firestein,et al.  Mitogen activated protein kinase inhibitors: where are we now and where are we going? , 2006, Annals of the rheumatic diseases.

[4]  L. Ferrucci,et al.  Interleukin-6 in aging and chronic disease: a magnificent pathway. , 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

[5]  J. Remacle,et al.  Establishment of H2O2‐Induced Premature Senescence in Human Fibroblasts Concomitant with Increased Cellular Production of H2O2 , 2006, Annals of the New York Academy of Sciences.

[6]  L. Ferrucci,et al.  Phenotype of frailty: characterization in the women's health and aging studies. , 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

[7]  R. Ransohoff,et al.  The many roles of chemokines and chemokine receptors in inflammation. , 2006, The New England journal of medicine.

[8]  D. DeFranco,et al.  Mechanism of action of Hic-5/androgen receptor activator 55, a LIM domain-containing nuclear receptor coactivator. , 2006, Molecular endocrinology.

[9]  Luigi Ferrucci,et al.  From bedside to bench: research agenda for frailty. , 2005, Science of aging knowledge environment : SAGE KE.

[10]  L. Ferrucci,et al.  Impact of anemia and cardiovascular disease on frailty status of community-dwelling older women: the Women's Health and Aging Studies I and II. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.

[11]  F. Dhabhar,et al.  Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation. , 2005 .

[12]  P. Romagnani,et al.  CXCR3-binding chemokines: novel multifunctional therapeutic targets. , 2005, Current drug targets. Immune, endocrine and metabolic disorders.

[13]  M H Barcellos-Hoff,et al.  How tissues respond to damage at the cellular level: orchestration by transforming growth factor-β (TGF-β) , 2005 .

[14]  L. Ginaldi,et al.  Phenotypic and functional changes of circulating monocytes and polymorphonuclear leucocytes from elderly persons , 2004, Immunology and cell biology.

[15]  S. Leng,et al.  Decreased cell proliferation and altered cytokine production in frail older adults , 2004, Aging clinical and experimental research.

[16]  S. Leng,et al.  Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty , 2004, Aging clinical and experimental research.

[17]  L. Ferrucci,et al.  Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

[18]  L. Ferrucci,et al.  Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. , 2003, The Journal of clinical endocrinology and metabolism.

[19]  R. Hotchkiss,et al.  The pathophysiology and treatment of sepsis. , 2003, The New England journal of medicine.

[20]  L. Fried,et al.  Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. , 2002, Archives of internal medicine.

[21]  T. Lawrence,et al.  Anti-inflammatory lipid mediators and insights into the resolution of inflammation , 2002, Nature Reviews Immunology.

[22]  P. Finan,et al.  IL‐10 expression profiling in human monocytes , 2002, Journal of leukocyte biology.

[23]  Kathleen Koenig,et al.  Serum Interleukin‐6 and Hemoglobin as Physiological Correlates in the Geriatric Syndrome of Frailty: A Pilot Study , 2002, Journal of the American Geriatrics Society.

[24]  L. Lipsitz Dynamics of stability: the physiologic basis of functional health and frailty. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

[25]  C. V. Jensen,et al.  Chemokines CXCL10 and CCL2: differential involvement in intrathecal inflammation in multiple sclerosis , 2001, European journal of neurology.

[26]  M. Shibanuma,et al.  Identification and Characterization of hic-5/ARA55 as an hsp27 Binding Protein* , 2001, The Journal of Biological Chemistry.

[27]  T. Mak,et al.  The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells , 2001, The Journal of experimental medicine.

[28]  M. Kronenberg,et al.  Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes , 2001, Nature Medicine.

[29]  G. Zhu,et al.  B7-H3: A costimulatory molecule for T cell activation and IFN-γ production , 2001, Nature Immunology.

[30]  L. Fried,et al.  Frailty in older adults: evidence for a phenotype. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[31]  H. Tsujimoto,et al.  Increased Monocyte Activation in Elderly Patients after Surgical Stress , 2001, European Surgical Research.

[32]  B. Rollins,et al.  Chemokines and disease , 2001, Nature Immunology.

[33]  G. Zhu,et al.  B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. , 2001, Nature immunology.

[34]  K. Matsushima,et al.  Comprehensive gene expression profile of LPS-stimulated human monocytes by SAGE. , 2000, Blood.

[35]  E. R. Sánchez,et al.  Heat and Chemical Shock Potentiation of Glucocorticoid Receptor Transactivation Requires Heat Shock Factor (HSF) Activity , 2000, The Journal of Biological Chemistry.

[36]  J. Fahey,et al.  Phenotypic and functional characteristics of circulating monocytes of elderly persons☆ , 1999, Experimental Gerontology.

[37]  J. Ouslander Principles of Geriatric Medicine and Gerontology , 1999 .

[38]  D. Sun,et al.  Lepidopteran DALP, and its mammalian ortholog HIC-5, function as negative regulators of muscle differentiation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[39]  K. Matsushima,et al.  Serial analysis of gene expression in human monocytes and macrophages. , 1999, Blood.

[40]  C. Ware,et al.  Lymphotoxin alphabeta is expressed on recently activated naive and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation. , 1999, Journal of immunology.

[41]  K. Nose,et al.  Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence. , 1994, The Journal of biological chemistry.

[42]  B. Aggarwal,et al.  Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity , 1984, Nature.