A comparative analysis of classification algorithms in diabetic retinopathy screening

Automated screening of diabetic retinopathy plays an important role in diagnosis of the disease in early stages and preventing blindness in patients with diabetes. Various machine learning approaches have been studied in literature with the purpose of improving the accuracy of the screening methods. Although the performance of the machine learning algorithm depends on the application and the type of data, yet there is no comprehensive analysis of different approaches in the diabetic retinopathy screening to choose the best approach. To this end, in this study a comparative analysis of nine common classification algorithms is performed to select the most applicable approach for the specific problem of screening diabetic retinopathy patients. Individual algorithms are optimized with respect to their tunable parameters, and are compared together in terms of their accuracy, precision, recall, and F1-score. Simulation results demonstrate the difference between the performances of individual classification algorithms and can be used as a deciding factor in method selection for further research.

[1]  Thomas G. Dietterich What is machine learning? , 2020, Archives of Disease in Childhood.

[2]  Qin Li,et al.  Retinopathy Online Challenge: Automatic Detection of Microaneurysms in Digital Color Fundus Photographs , 2010, IEEE Transactions on Medical Imaging.

[3]  Bálint Antal,et al.  An ensemble-based system for automatic screening of diabetic retinopathy , 2014, Knowl. Based Syst..

[4]  Robert E. Schapire,et al.  Explaining AdaBoost , 2013, Empirical Inference.

[5]  Qian Du,et al.  Collaborative-Representation-Based Nearest Neighbor Classifier for Hyperspectral Imagery , 2015, IEEE Geoscience and Remote Sensing Letters.

[6]  Alireza Osareh,et al.  A Computational-Intelligence-Based Approach for Detection of Exudates in Diabetic Retinopathy Images , 2009, IEEE Transactions on Information Technology in Biomedicine.

[7]  Jorge de la Calleja,et al.  Image-based classification of diabetic retinopathy using machine learning , 2012, 2012 12th International Conference on Intelligent Systems Design and Applications (ISDA).

[8]  Amol Prataprao Bhatkar,et al.  Detection of Diabetic Retinopathy in Retinal Images Using MLP Classifier , 2015, 2015 IEEE International Symposium on Nanoelectronic and Information Systems.

[9]  B. Thomas,et al.  Automated identification of diabetic retinal exudates in digital colour images , 2003, The British journal of ophthalmology.

[10]  Shehzad Khalid,et al.  Detection and classification of retinal lesions for grading of diabetic retinopathy , 2014, Comput. Biol. Medicine.

[11]  Bálint Antal,et al.  An Ensemble-Based System for Microaneurysm Detection and Diabetic Retinopathy Grading , 2012, IEEE Transactions on Biomedical Engineering.

[12]  H. A. Nugroho,et al.  Gaussian Bayes classifier for medical diagnosis and grading: Application to diabetic retinopathy , 2010, 2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES).

[13]  P. Aruna,et al.  DIAGNOSIS OF DIABETIC RETINOPATHY USING MACHINE LEARNING TECHNIQUES , 2013, SOCO 2013.

[14]  Muhammad Younus Javed,et al.  Detection of neovascularization in retinal images using multivariate m-Mediods based classifier , 2013, Comput. Medical Imaging Graph..

[15]  Kenneth W. Tobin,et al.  Exudate-based diabetic macular edema detection in fundus images using publicly available datasets , 2012, Medical Image Anal..

[16]  N. Congdon,et al.  The worldwide epidemic of diabetic retinopathy , 2012, Indian journal of ophthalmology.

[17]  Martin T. Hagan,et al.  Neural network design , 1995 .

[18]  C. Sundhar,et al.  Automatic Screening of Fundus Images for Detection of Diabetic Retinopathy , 2019, International Journal of communication and computer Technologies.

[19]  Vasile Palade,et al.  Automatic detection of microaneurysms in colour fundus images for diabetic retinopathy screening , 2015, Neural Computing and Applications.

[20]  Giri Babu Kande,et al.  Automatic Detection of Microaneurysms and Hemorrhages in Digital Fundus Images , 2010, Journal of Digital Imaging.

[21]  Panos M. Pardalos,et al.  Data Mining in Agriculture , 2008 .

[22]  Gwénolé Quellec,et al.  Exudate detection in color retinal images for mass screening of diabetic retinopathy , 2014, Medical Image Anal..

[23]  Daniel T. Larose,et al.  Discovering Knowledge in Data: An Introduction to Data Mining , 2005 .