Satellite cell activation and apoptosis in skeletal muscle from severely burned children

Severe burns result in profound skeletal muscle atrophy that hampers recovery. The activity of skeletal muscle stem cells, satellite cells, acutely following a severe burn is unknown and may contribute to the recovery of lean muscle. Severe burn injury induces skeletal muscle regeneration and myonuclear apoptosis. Satellite cells undergo concurrent apoptosis and activation acutely following a burn, with a net reduction in satellite cell content compared to healthy controls. The activation and apoptosis of satellite cells probably impacts the recovery of lean tissue following a severe burn, contributing to prolonged frailty in burn survivors.

[1]  M. Kjaer,et al.  Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti‐inflammatory medication , 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[2]  Christopher S. Fry,et al.  Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults. , 2016, Journal of applied physiology.

[3]  L. Verdijk,et al.  Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance‐type exercise training , 2016, Acta physiologica.

[4]  B. Olwin,et al.  Pervasive satellite cell contribution to uninjured adult muscle fibers , 2015, Skeletal Muscle.

[5]  S. Wolf,et al.  Skeletal Muscle Loss is Associated with TNF Mediated Insufficient Skeletal Myogenic Activation After Burn , 2015, Shock.

[6]  P. Macdonald,et al.  Atrophy, inducible satellite cell activation, and possible denervation of supraspinatus muscle in injured human rotator-cuff muscle. , 2015, American journal of physiology. Cell physiology.

[7]  S. Windham,et al.  Serum from human burn victims impairs myogenesis and protein synthesis in primary myoblasts , 2015, Front. Physiol..

[8]  L. Sidossis,et al.  Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns. , 2015, Burns : journal of the International Society for Burn Injuries.

[9]  Hui-chao Yan,et al.  Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells , 2015, Journal of Zhejiang University-SCIENCE B.

[10]  M. Yandell,et al.  Muscle stem cells contribute to myofibers in sedentary adult mice , 2015, Nature Communications.

[11]  J. Tidball.  Faculty Opinions recommendation of Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia. , 2015 .

[12]  D. Herndon,et al.  The Role of Exercise in the Rehabilitation of Patients with Severe Burns , 2015, Exercise and sport sciences reviews.

[13]  F. Hölzle,et al.  Nrf2 augments skeletal muscle regeneration after ischaemia–reperfusion injury , 2014, The Journal of pathology.

[14]  C. Andersen,et al.  Impact of stress-induced diabetes on outcomes in severely burned children. , 2014, Journal of the American College of Surgeons.

[15]  J. McCarthy,et al.  Regulation of the muscle fiber micro environment by activated satellite cells during hypertrophy , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[16]  Fujun Liu,et al.  Automated fiber-type-specific cross-sectional area assessment and myonuclei counting in skeletal muscle. , 2013, Journal of applied physiology.

[17]  Charles Keller,et al.  NF-κB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. , 2013, The Journal of clinical investigation.

[18]  T. Delhaas,et al.  Satellite cells in human skeletal muscle; from birth to old age , 2013, AGE.

[19]  J. Ryall.  Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration , 2013, The FEBS journal.

[20]  S. Windham,et al.  Increased Expression of Atrogenes and TWEAK Family Members after Severe Burn Injury in Nonburned Human Skeletal Muscle , 2013, Journal of burn care & research : official publication of the American Burn Association.

[21]  T. Walters,et al.  Skeletal muscle satellite cell activation following cutaneous burn in rats. , 2013, Burns : journal of the International Society for Burn Injuries.

[22]  Marco Quarta,et al.  Collagen VI regulates satellite cell self-renewal and muscle regeneration , 2013, Nature Communications.

[23]  J. Cross,et al.  Inflammatory and Protein Metabolism Signaling Responses in Human Skeletal Muscle After Burn Injury , 2012, Journal of burn care & research : official publication of the American Burn Association.

[24]  Christoph Lepper,et al.  An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration , 2011, Development.

[25]  D. Herndon,et al.  Long-Term Persistance of the Pathophysiologic Response to Severe Burn Injury , 2011, PloS one.

[26]  D. Joshi,et al.  Electrophysiological and histological changes in extrinsic muscles proximal to post burn contractures of hand. , 2011, Burns : journal of the International Society for Burn Injuries.

[27]  C. Mann,et al.  Aberrant repair and fibrosis development in skeletal muscle , 2011, Skeletal Muscle.

[28]  T. Walters,et al.  Muscle contractile properties in severely burned rats. , 2010, Burns : journal of the International Society for Burn Injuries.

[29]  S. Thrun,et al.  Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture , 2010, Science.

[30]  G. Butler-Browne,et al.  Impaired Skeletal Muscle Repair after Ischemia-Reperfusion Injury in Mice , 2010, Journal of biomedicine & biotechnology.

[31]  H. Yin,et al.  [Changes in proliferative activity of myoblasts and expression of Akt in skeletal muscle of rats after severe burn injury]. , 2009, Zhonghua wai ke za zhi [Chinese journal of surgery].

[32]  M. Tarnopolsky,et al.  Hepatocyte growth factor (HGF) and the satellite cell response following muscle lengthening contractions in humans , 2008, Muscle & nerve.

[33]  B. Taira,et al.  Apoptosis and necrosis in the ischemic zone adjacent to third degree burns. , 2008, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[34]  J. Petrella,et al.  Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis. , 2008, Journal of applied physiology.

[35]  E. Hoffman,et al.  Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. , 2008, Developmental cell.

[36]  C. Keller,et al.  Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis , 2007, Science.

[37]  David J. Kosek,et al.  Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women. , 2006, American journal of physiology. Endocrinology and metabolism.

[38]  M. Molinaro,et al.  Tumor necrosis factor‐α gene transfer induces cachexia and inhibits muscle regeneration , 2005 .

[39]  D. Herndon,et al.  Post burn muscle wasting and the effects of treatments. , 2005, The international journal of biochemistry & cell biology.

[40]  R. Tompkins,et al.  Support of the metabolic response to burn injury , 2004, The Lancet.

[41]  L. McLoon,et al.  Continuous myofiber remodeling in uninjured extraocular myofibers: Myonuclear turnover and evidence for apoptosis , 2004, Muscle & nerve.

[42]  G. Biolo,et al.  Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients. , 2002, The Journal of clinical endocrinology and metabolism.

[43]  N. Rosenthal,et al.  The Role of Stem Cells in Skeletal and Cardiac Muscle Repair , 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[44]  C. Ibebunjo,et al.  Disparate dysfunction of skeletal muscles located near and distant from burn site in the rat , 2001, Muscle and Nerve.

[45]  M. Kaneki,et al.  Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals. , 2000, American journal of physiology. Endocrinology and metabolism.

[46]  D. Chinkes,et al.  Determinants of Skeletal Muscle Catabolism After Severe Burn , 2000, Annals of surgery.

[47]  D. Chinkes,et al.  Persistence of muscle catabolism after severe burn. , 2000, Surgery.

[48]  R. Demling,et al.  ANTICATABOLIC AND ANABOLIC STRATEGIES IN CRITICAL ILLNESS: A REVIEW OF CURRENT TREATMENT MODALITIES , 1998, Shock.

[49]  R. Wolfe,et al.  Dynamics of the protein metabolic response to burn injury. , 1988, Metabolism: clinical and experimental.

[50]  C. P. Leblond,et al.  Satellite cells as the source of nuclei in muscles of growing rats , 1971, The Anatomical record.

[51]  D. Ribeiro,et al.  Temporal study following burn injury in young rats is associated with skeletal muscle atrophy, inflammation and altered myogenic regulatory factors , 2014, Inflammation Research.

[52]  D. Herndon,et al.  Whole body and skeletal muscle protein turnover in recovery from burns. , 2013, International journal of burns and trauma.

[53]  H. Yin,et al.  Effect of burn injury on apoptosis and expression of apoptosis-related genes/proteins in skeletal muscles of rats , 2008, Apoptosis.

[54]  S. Asko-Seljavaara,et al.  Long‐term morphometric and immunohistochemical findings in human free microvascular muscle flaps , 2004, Microsurgery.

[55]  M. Toader-Radu.  Dynamics of regeneration in skeletal muscle following localized heat injury. , 1978, Morphologie et embryologie.

[56]  J. Bergstrom.  Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. , 1975, Scandinavian journal of clinical and laboratory investigation.

[57]  Jennifer A. Lawson,et al.  Satellite cells , connective tissue fibroblasts and their interactions are crucial for muscle regeneration , 2022 .