Lanthanum chloride causes blood-brain barrier disruption through intracellular calcium-mediated RhoA/Rho kinase signaling and myosin light chain kinase.
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Yuan Cai | Cuihong Jin | Jinghua Yang | Sheng-wen Wu | Wenchang Sun | Xiaobo Lu | Miao Yu | Yarao Han | Jie Wu
[1] Yuan Cai,et al. Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats. , 2020, Metallomics : integrated biometal science.
[2] Yuan Cai,et al. Lanthanum Chloride Impairs Learning and Memory and Induces Dendritic Spine Abnormality by Down-Regulating Rac1/PAK Signaling Pathway in Hippocampus of Offspring Rats , 2019, Cellular and Molecular Neurobiology.
[3] W. Kong,et al. Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease. , 2019, Cellular signalling.
[4] Sheng-Yong Luo,et al. Anfibatide Preserves Blood–Brain Barrier Integrity by Inhibiting TLR4/RhoA/ROCK Pathway After Cerebral Ischemia/Reperfusion Injury in Rat , 2019, Journal of Molecular Neuroscience.
[5] Eunhee Kim,et al. Blood–Brain Barrier Dysfunction in a 3D In Vitro Model of Alzheimer's Disease , 2019, Advanced science.
[6] Liling Huang,et al. Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microglia. , 2019, Metallomics : integrated biometal science.
[7] J. Worthington,et al. Molecular neurochemistry of the lanthanides , 2019, Synapse.
[8] P. Thomas,et al. Human exposures to rare earth elements: Present knowledge and research prospects , 2018, Environmental research.
[9] Zhigang Chen,et al. The Role of VE-cadherin in Blood-brain Barrier Integrity under Central Nervous System Pathological Conditions , 2018, Current neuropharmacology.
[10] Huifeng Zhu,et al. RhoA/ROCK-2 Pathway Inhibition and Tight Junction Protein Upregulation by Catalpol Suppresses Lipopolysaccaride-Induced Disruption of Blood-Brain Barrier Permeability , 2018, Molecules.
[11] W. Gwenzi,et al. Sources, behaviour, and environmental and human health risks of high-technology rare earth elements as emerging contaminants. , 2018, The Science of the total environment.
[12] Liling Huang,et al. Conditioned medium from overly excitatory primary astrocytes induced by La3+ increases apoptosis in primary neurons via upregulating the expression of NMDA receptors. , 2018, Metallomics : integrated biometal science.
[13] Lijin Zhang,et al. Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats , 2018, Biological Trace Element Research.
[14] K. Borowiak,et al. Relationship between concentration of rare earth elements in soil and their distribution in plants growing near a frequented road , 2018, Environmental Science and Pollution Research.
[15] C. Turra. Sustainability of rare earth elements chain: from production to food – a review , 2018, International journal of environmental health research.
[16] J. Waschke,et al. Mind the gap: mechanisms regulating the endothelial barrier , 2018, Acta physiologica.
[17] Lijin Zhang,et al. Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors. , 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[18] D. Antonetti,et al. The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers , 2017, Tissue barriers.
[19] Jiao Sun,et al. Blood-brain barrier dysfunction induced by silica NPs in vitro and in vivo: Involvement of oxidative stress and Rho-kinase/JNK signaling pathways. , 2017, Biomaterials.
[20] Lijin Zhang,et al. The effect of nuclear factor erythroid 2‐related factor/antioxidant response element signalling pathway in the lanthanum chloride‐induced impairment of learning and memory in rats , 2017, Journal of neurochemistry.
[21] M. Badoual,et al. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity , 2015, The Journal of cell biology.
[22] B. Kalionis,et al. Aβ1–42 oligomer‐induced leakage in an in vitro blood–brain barrier model is associated with up‐regulation of RAGE and metalloproteinases, and down‐regulation of tight junction scaffold proteins , 2015, Journal of neurochemistry.
[23] Xin Wei,et al. Increasing the Permeability of the Blood–brain Barrier in Three Different Models in vivo , 2015, CNS neuroscience & therapeutics.
[24] Britta Engelhardt,et al. Brain barriers: Crosstalk between complex tight junctions and adherens junctions , 2015, The Journal of cell biology.
[25] R. Daneman,et al. The blood-brain barrier. , 2015, Cold Spring Harbor perspectives in biology.
[26] R. Vandenbroucke,et al. A new angle on blood–CNS interfaces: A role for connexins? , 2014, FEBS letters.
[27] E. Elamin,et al. Ethanol disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated Rho/ROCK activation. , 2014, American journal of physiology. Gastrointestinal and liver physiology.
[28] R. Ransohoff,et al. Development, maintenance and disruption of the blood-brain barrier , 2013, Nature Medicine.
[29] A. Gadicherla,et al. Endothelial calcium dynamics, connexin channels and blood–brain barrier function , 2013, Progress in Neurobiology.
[30] Linlin Zheng,et al. Lanthanum chloride impairs spatial learning and memory and downregulates NF-κB signalling pathway in rats , 2013, Archives of Toxicology.
[31] Say Chye Joachim Loo,et al. Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE–cadherin , 2013, Nature Communications.
[32] T. Nishioku,et al. Paracellular barrier and tight junction protein expression in the immortalized brain endothelial cell lines bEND.3, bEND.5 and mouse brain endothelial cell 4. , 2013, Biological & pharmaceutical bulletin.
[33] S. Rohrbach,et al. Hypoxia–reoxygenation‐induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase , 2013, The Journal of physiology.
[34] C. Ha,et al. Aβ1–42-RAGE Interaction Disrupts Tight Junctions of the Blood–Brain Barrier Via Ca2+-Calcineurin Signaling , 2012, The Journal of Neuroscience.
[35] D. Hermann,et al. Liver X Receptor Activation Enhances Blood–Brain Barrier Integrity in the Ischemic Brain and Increases the Abundance of ATP‐Binding Cassette Transporters ABCB1 and ABCC1 on Brain Capillary Cells , 2012, Brain pathology.
[36] N. Abbott,et al. An improved in vitro blood-brain barrier model: rat brain endothelial cells co-cultured with astrocytes. , 2012, Methods in molecular biology.
[37] Z. Chai,et al. Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.
[38] Rachel C Brown,et al. Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells , 2007, Brain Research.
[39] Z. Chai,et al. Long-term effects of lanthanum intake on the neurobehavioral development of the rat. , 2006, Neurotoxicology and teratology.
[40] L. Fenart,et al. Mouse syngenic in vitro blood–brain barrier model: a new tool to examine inflammatory events in cerebral endothelium , 2005, Laboratory Investigation.
[41] L. Campbell,et al. Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies , 2003, Brain Research.