Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress
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S. Miyamoto | Zhao-Hui Wu | Tony T. Huang | Shigeki Miyamoto | Tony T Huang | Zhao-Hui Wu | Shelly M Wuerzberger-Davis | S. Wuerzberger-Davis
[1] C. Holmberg,et al. Phosphorylation of Serine 303 Is a Prerequisite for the Stress-Inducible SUMO Modification of Heat Shock Factor 1 , 2003, Molecular and Cellular Biology.
[2] A. Dejean,et al. Conjugation with the ubiquitin‐related modifier SUMO‐1 regulates the partitioning of PML within the nucleus , 1998, The EMBO journal.
[3] Seth J Davis,et al. The Small Ubiquitin-like Modifier (SUMO) Protein Modification System in Arabidopsis , 2003, The Journal of Biological Chemistry.
[4] S. Shumway,et al. Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells , 1998, Molecular and Cellular Biology.
[5] Shao-Cong Sun,et al. Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: hijacking cellular IκB kinases , 1999, Oncogene.
[6] Boris Pfander,et al. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO , 2002, Nature.
[7] J. Dixon,et al. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. , 2000, Science.
[8] S. Ghosh,et al. Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex , 2000 .
[9] M. Karin,et al. The Carboxyl-Terminal Region of IκB Kinase γ (IKKγ) Is Required for Full IKK Activation , 2002, Molecular and Cellular Biology.
[10] J. Pober,et al. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. , 2000, Science.
[11] G. Courtois,et al. ATM Is Required for IκB Kinase (IKK) Activation in Response to DNA Double Strand Breaks* , 2000, The Journal of Biological Chemistry.
[12] S. Elledge,et al. The DNA damage response: putting checkpoints in perspective , 2000, Nature.
[13] Brian D. Strahl,et al. A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression , 2003, Nature.
[14] L. Zon,et al. SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. , 2002, Molecular cell.
[15] I. Verma,et al. NF-κB regulation in the immune system , 2002, Nature Reviews Immunology.
[16] S. Elledge,et al. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. , 2000, Genes & development.
[17] C. Pickart,et al. Mechanisms underlying ubiquitination. , 2001, Annual review of biochemistry.
[18] Nanxin Li,et al. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[19] T. Hunter,et al. Signaling—2000 and Beyond , 2000, Cell.
[20] S. Miyamoto,et al. Postrepression Activation of NF-κB Requires the Amino-Terminal Nuclear Export Signal Specific to IκBα , 2001, Molecular and Cellular Biology.
[21] E. Elion,et al. Nuclear Shuttling of Yeast Scaffold Ste5 Is Required for Its Recruitment to the Plasma Membrane and Activation of the Mating MAPK Cascade , 1999, Cell.
[22] Chi A. Ma,et al. Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia , 2001, Nature Immunology.
[23] H. Nakano,et al. The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation. , 2003, Genes & development.
[24] M. Karin,et al. The mammalian ultraviolet response is triggered by activation of src tyrosine kinases , 1992, Cell.
[25] A. Fischer,et al. X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling , 2001, Nature Genetics.
[26] M. Kastan,et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.
[27] S. Miyamoto,et al. The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors , 2002, Molecular and Cellular Biology.
[28] R. Hay,et al. SUMO-1 Conjugation in Vivo Requires Both a Consensus Modification Motif and Nuclear Targeting* , 2001, The Journal of Biological Chemistry.
[29] Sheng-Cai Lin,et al. SUMO-1 Modification of the C-terminal KVEKVD of Axin Is Required for JNK Activation but Has No Effect on Wnt Signaling* , 2002, The Journal of Biological Chemistry.
[30] G. Courtois,et al. The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination , 2003, Nature.
[31] A. Israël,et al. Induction of the NF-κB Cascade by Recruitment of the Scaffold Molecule NEMO to the T Cell Receptor , 2003 .
[32] John Calvin Reed,et al. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. , 2000, Science.
[33] Zhijian J. Chen,et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK , 2001, Nature.
[34] T. Hunter,et al. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus , 1995, Current Biology.
[35] L. Liu,et al. SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[36] R. Hay,et al. SUMO‐1 modification activates the transcriptional response of p53 , 1999, The EMBO journal.
[37] S. Shumway,et al. NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. , 2000, The Journal of biological chemistry.
[38] A. Dejean,et al. Nuclear and unclear functions of SUMO , 2003, Nature Reviews Molecular Cell Biology.
[39] A. Ashworth,et al. CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members , 2003, Nature.
[40] R. Gaynor,et al. Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression , 2003, Nature.
[41] R. Hay,et al. SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. , 1998, Molecular cell.
[42] A. Caudy,et al. Regulation of Transcriptional Activation Domain Function by Ubiquitin , 2001, Science.
[43] F. Melchior,et al. A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2 , 1997, Cell.
[44] R. Abraham. Cell cycle checkpoint signaling through the ATM and ATR kinases. , 2001, Genes & development.
[45] René Bernards,et al. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB , 2003, Nature.
[46] W. Tam,et al. IkappaB family members function by different mechanisms. , 2001, The Journal of biological chemistry.
[47] S. Jentsch,et al. Ubiquitin and proteasomes: Sumo, ubiquitin's mysterious cousin , 2001, Nature Reviews Molecular Cell Biology.
[48] Minoru Yoshida,et al. A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes , 2000 .
[49] W. Tam,et al. IκB Family Members Function by Different Mechanisms* , 2001, The Journal of Biological Chemistry.
[50] Michael Karin,et al. NF-κB in cancer: from innocent bystander to major culprit , 2002, Nature Reviews Cancer.
[51] Zhijian J. Chen,et al. Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.
[52] G. Ghosh,et al. IκBβ, but Not IκBα, Functions as a Classical Cytoplasmic Inhibitor of NF-κB Dimers by Masking Both NF-κB Nuclear Localization Sequences in Resting Cells* , 2001, The Journal of Biological Chemistry.
[53] S. Klauck,et al. Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti , 2000, Nature.
[54] D. Baltimore,et al. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. , 1988, Science.
[55] G. Blobel,et al. A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex , 1996, The Journal of cell biology.
[56] G. Luo,et al. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation , 2003, Oncogene.
[57] M. Kastan,et al. The many substrates and functions of ATM , 2000, Nature Reviews Molecular Cell Biology.