Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors.
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Robert P. DePianta | V. Shanmugasundaram | A. Brown | P. Fish | C. D. de Oliveira | P. Brennan | A. Heifetz | P. Bungay | G. McMurray | G. Whitlock | R. I. Storer | Alan S. Jessiman | Lee R. Roberts | D. Westbrook | M. Shapiro | K. Conlon | M. Corbett | J. Root | S. Wheeler | John Wright | D. H. Ho | Melanie Skerten | Danny K. H. Ho | James A Root | J. Wright | Alexander Heifetz