Cell type-resolved human lung lipidome reveals cellular cooperation in lung function

[1]  Ravi S. Misra,et al.  The Importance of Vaccinating Children and Pregnant Women against Influenza Virus Infection , 2019, Pathogens.

[2]  J. Adkins,et al.  Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells , 2019, mBio.

[3]  Jason R. Myers,et al.  Dissociation, cellular isolation, and initial molecular characterization of neonatal and pediatric human lung tissues. , 2018, American journal of physiology. Lung cellular and molecular physiology.

[4]  Matthias Mann,et al.  Region and cell-type resolved quantitative proteomic map of the human heart , 2017, Nature Communications.

[5]  A. Birukova,et al.  Effects of prostaglandin lipid mediators on agonist-induced lung endothelial permeability and inflammation. , 2017, American journal of physiology. Lung cellular and molecular physiology.

[6]  Thomas O. Metz,et al.  LIQUID: an‐open source software for identifying lipids in LC‐MS/MS‐based lipidomics data , 2017, Bioinform..

[7]  I. Lodhi,et al.  Structural and functional roles of ether lipids , 2017, Protein & Cell.

[8]  S. Schlager,et al.  Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages , 2017, Oncotarget.

[9]  Sydney E. Dautel,et al.  Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung , 2017, Scientific Reports.

[10]  Ravi S. Misra,et al.  Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development , 2017, Thorax.

[11]  James P. Carson,et al.  Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples , 2016, Scientific Reports.

[12]  B. Stripp,et al.  Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. , 2016, JCI insight.

[13]  V. Novakovic,et al.  Phosphatidylserine on blood cells and endothelial cells contributes to the hypercoagulable state in cirrhosis , 2016, Liver international : official journal of the International Association for the Study of the Liver.

[14]  C. Bult,et al.  Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development , 2016, PeerJ.

[15]  Kristin E. Burnum-Johnson,et al.  MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses , 2016, mSystems.

[16]  Ronald J Moore,et al.  Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry. , 2016, The Analyst.

[17]  Baoxin Li,et al.  Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release , 2015, PloS one.

[18]  Matthias Mann,et al.  Cell type– and brain region–resolved mouse brain proteome , 2015, Nature Neuroscience.

[19]  Jody C. May,et al.  Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer. , 2015, The Analyst.

[20]  S. Schlager,et al.  Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis , 2015, Journal of leukocyte biology.

[21]  E. White.  Commentary: A Breath of Fresh Air on the Mesenchyme: Impact of Impaired Mesenchymal Development on the Pathogenesis of Bronchopulmonary Dysplasia , 2015, Front. Med..

[22]  S. Bellusci,et al.  A Breath of Fresh Air on the Mesenchyme: Impact of Impaired Mesenchymal Development on the Pathogenesis of Bronchopulmonary Dysplasia , 2015, Front. Med..

[23]  D. Mcculley,et al.  The Pulmonary Mesenchyme Directs Lung Development , 2015, Current opinion in genetics & development.

[24]  L. Ermini,et al.  Sphingolipids as cell fate regulators in lung development and disease , 2015, Apoptosis.

[25]  G. Schmitz,et al.  Surfactant Lipidomics in Healthy Children and Childhood Interstitial Lung Disease , 2015, PloS one.

[26]  Yehia M. Ibrahim,et al.  Development of a new ion mobility time-of-flight mass spectrometer , 2015 .

[27]  G. von Heijne,et al.  Tissue-based map of the human proteome , 2015, Science.

[28]  T. Graham,et al.  Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution , 2015, Traffic.

[29]  J. Whitsett,et al.  Respiratory epithelial cells orchestrate pulmonary innate immunity , 2014, Nature Immunology.

[30]  M. Mann,et al.  Cell-type-resolved quantitative proteomics of murine liver. , 2014, Cell metabolism.

[31]  S. Schlager,et al.  Adipose triglyceride lipase regulates eicosanoid production in activated human mast cells , 2014, Journal of Lipid Research.

[32]  K. Ahlbrecht,et al.  In search of the elusive lipofibroblast in human lungs. , 2014, American journal of physiology. Lung cellular and molecular physiology.

[33]  M. Ochs,et al.  How common is the lipid body-containing interstitial cell in the mammalian lung? , 2014, American journal of physiology. Lung cellular and molecular physiology.

[34]  P. Greimel,et al.  Lipid compartmentalization in the endosome system. , 2014, Seminars in cell & developmental biology.

[35]  N. Neff,et al.  Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq , 2014, Nature.

[36]  Cody R. Goodwin,et al.  Conformational Ordering of Biomolecules in the Gas Phase: Nitrogen Collision Cross Sections Measured on a Prototype High Resolution Drift Tube Ion Mobility-Mass Spectrometer , 2014, Analytical chemistry.

[37]  P. Kovanen,et al.  Mast cells: from lipid droplets to lipid mediators , 2013, Clinical science.

[38]  R. Mallampalli,et al.  Surfactant phospholipid metabolism. , 2013, Biochimica et biophysica acta.

[39]  Susan E. Wert,et al.  Transcriptional Programs Controlling Perinatal Lung Maturation , 2012, PloS one.

[40]  J. Whitsett,et al.  Activation of Sterol-response Element-binding Proteins (SREBP) in Alveolar Type II Cells Enhances Lipogenesis Causing Pulmonary Lipotoxicity* , 2012, The Journal of Biological Chemistry.

[41]  V. V. van Hinsbergh.  Endothelium—role in regulation of coagulation and inflammation , 2011, Seminars in immunopathology.

[42]  Taras V. Pogorelov,et al.  Molecular Determinants of Phospholipid Synergy in Blood Clotting* , 2011, The Journal of Biological Chemistry.

[43]  Yasuo Okamoto,et al.  Roles of sphingosine-1-phosphate signaling in angiogenesis. , 2010, World journal of biological chemistry.

[44]  P. Williamson,et al.  Phospholipid scramblase: An update , 2010, FEBS letters.

[45]  J. Whitsett,et al.  Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. , 2010, American journal of physiology. Lung cellular and molecular physiology.

[46]  Paul O Nkadi,et al.  An overview of pulmonary surfactant in the neonate: genetics, metabolism, and the role of surfactant in health and disease. , 2009, Molecular genetics and metabolism.

[47]  Robert V Farese,et al.  Lipid droplets at a glance , 2009, Journal of Cell Science.

[48]  J. Whitsett,et al.  Deletion of Scap in Alveolar Type II Cells Influences Lung Lipid Homeostasis and Identifies a Compensatory Role for Pulmonary Lipofibroblasts* , 2009, Journal of Biological Chemistry.

[49]  Takao Shimizu.  Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. , 2009, Annual review of pharmacology and toxicology.

[50]  I. Petrache,et al.  Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. , 2008, American journal of respiratory cell and molecular biology.

[51]  Sébastien Lê,et al.  FactoMineR: An R Package for Multivariate Analysis , 2008 .

[52]  M. Lagarde,et al.  De novo biosynthesis of the late endosome lipid, bis(monoacylglycero)phosphates⃞ Published, JLR Papers in Press, June 8, 2007. , 2007, Journal of Lipid Research.

[53]  Elena Alekseeva,et al.  Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation. , 2007, Experimental cell research.

[54]  J. Huot,et al.  Endothelial cell migration during angiogenesis. , 2007, Circulation research.

[55]  Ying Huang,et al.  Phospholipid scramblase 1. , 2006, Sheng li xue bao : [Acta physiologica Sinica].

[56]  P. Verhamme,et al.  THE PIVOTAL ROLE OF THE ENDOTHELIUM IN HAEMOSTASIS AND THROMBOSIS , 2006, Acta clinica Belgica.

[57]  M. Mucenski,et al.  Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[58]  M. Keane,et al.  EVIDENCE FOR THE PRESENCE OF LIPOFIBROBLASTS IN HUMAN LUNG , 2006, Experimental lung research.

[59]  S. Chae,et al.  Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference. , 2004, The Journal of clinical investigation.

[60]  J. Rubins,et al.  Alveolar macrophages: wielding the double-edged sword of inflammation. , 2003, American journal of respiratory and critical care medicine.

[61]  B. Sumpio,et al.  Cells in focus: endothelial cell. , 2002, The international journal of biochemistry & cell biology.

[62]  P. Cosson,et al.  Separation and Characterization of Late Endosomal Membrane Domains* , 2002, The Journal of Biological Chemistry.

[63]  P. Williamson,et al.  Phosphatidylserine, a death knell , 2001, Cell Death and Differentiation.

[64]  D. Speert,et al.  Role of Pulmonary Alveolar Macrophages in Defense of the Lung against Pseudomonas aeruginosa , 2000, Infection and Immunity.

[65]  J. Torday,et al.  Metabolism and fate of neutral lipids of fetal lung fibroblast origin. , 1995, Biochimica et biophysica acta.

[66]  R. Wykle,et al.  1-O-alkyl-linked glycerophospholipids of human neutrophils: distribution of arachidonate and other acyl residues in the ether-linked and diacyl species. , 1984, Journal of lipid research.

[67]  R. Wykle,et al.  1-O-alkyl-linked phosphoglycerides of human platelets: Distribution of arachidonate and other acyl residues in the ether-linked and diacyl species , 1983, Lipids.

[68]  F. Dameron,et al.  Pulmonary di-and-triacylglycerols during the perinatal development of the rat , 1981, Experientia.

[69]  T. Stossel,et al.  Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles. , 1972, The Journal of clinical investigation.

[70]  Florey,et al.  The endothelial cell. , 1966, British medical journal.

[71]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[72]  J. Pérez-Gil,et al.  Pulmonary surfactant metabolism in the alveolar airspace: Biogenesis, extracellular conversions, recycling. , 2017, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.

[73]  P. Williamson,et al.  Supplementary Issue: Cellular Anatomy of Lipid Traffic , 2016 .

[74]  M. Post,et al.  Sphingolipids in lung growth and repair. , 2014, Chest.

[75]  E. Kelly,et al.  an update on , 2014 .

[76]  T. Hla,et al.  S1P control of endothelial integrity. , 2014, Current topics in microbiology and immunology.

[77]  V. Hinsbergh.  Endothelium—role in regulation of coagulation and inflammation , 2011, Seminars in Immunopathology.

[78]  S. Bhattacharya,et al.  Transcriptomic analysis of human lung development. , 2010, American journal of respiratory and critical care medicine.

[79]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[80]  M. Post,et al.  Lung development and fetal lung growth. , 2004, Paediatric respiratory reviews.

[81]  J. Torday,et al.  The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development. , 1997, Annual review of physiology.

[82]  D. Letourneur,et al.  Lipid composition of cultured endothelial cells in relation to their growth , 1997, Lipids.

[83]  G. Zimmerman,et al.  Lipid metabolism and signal transduction in endothelial cells. , 1990, Progress in lipid research.

[84]  K. Wu,et al.  Endothelial cell function in hemostasis and thrombosis. , 1988, Advances in experimental medicine and biology.