Surgical Management of Multijoint Septic Arthritis due to Rat-Bite Fever in a Pediatric Patient: A Case Study

In the United States, rat-bite fever is a rare systemic illness principally caused by Streptobacillus moniliformis, an organism found in the nasopharyngeal flora of rodents. Infection through direct exposure to rat excreta such as saliva, urine, or feces can lead to fever, rash, and an asymmetric migratory polyarthritis. As rodents are becoming more popular as pets, more pediatric cases are being documented. We report a pediatric case of delayed onset septic arthritis in the left wrist and right knee due to S. moniliformis from a rat bite. Previously reported pediatric case studies of suppurative arthritis due to S. moniliformis have only involved the hip. This case study demonstrates the importance of a thorough exposure history and consideration of zoonotic infections as a cause of septic arthritis in a pediatric patient that requires antibiotics and surgical intervention.

[1]  L. Averill,et al.  Septic Arthritis and Concern for Osteomyelitis in a Child with Rat Bite Fever , 2013, Journal of Clinical Microbiology.

[2]  S. Vanderhooft,et al.  Rat Bite Fever: Fever, Arthritis, and Rash in a 4‐Year‐Old Boy , 2012, Pediatric dermatology.

[3]  T. Wang,et al.  Streptobacillus moniliformis septic arthritis: a clinical entity distinct from rat-bite fever? , 2007, BMC infectious diseases.

[4]  S. Elliott Rat Bite Fever and Streptobacillus moniliformis , 2007, Clinical Microbiology Reviews.

[5]  T. Korman,et al.  Rat-bite fever septic arthritis: illustrative case and literature review , 2006, European Journal of Clinical Microbiology and Infectious Diseases.

[6]  P. Radford,et al.  A rare and serious consequence of a rat bite. , 2001, Annals of the Royal College of Surgeons of England.

[7]  J. Ogle,et al.  Index of suspicion. Case 1. Diagnosis: Rat-bite fever. , 2001, Pediatrics in review.

[8]  J. Janda,et al.  Rat-bite fever (Streptobacillus moniliformis): a potential emerging disease. , 2001, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[9]  Lindall E. Smith,et al.  Septic Arthritis of the Hip Secondary to Rat Bite Fever: A Case Report , 2000, Clinical orthopaedics and related research.

[10]  A. Reiner,et al.  Streptobacillus moniliformis polyarthritis mimicking rheumatoid arthritis: an urban case of rat bite fever. , 1988, The American journal of medicine.

[11]  L. White,et al.  Rat-bite fever as a cause of septic arthritis: a diagnostic dilemma. , 1987, Annals of the rheumatic diseases.

[12]  G. Joiner,et al.  Clinical microbiological, and histological manifestations of Streptobacillus moniliformis-induced arthritis in mice , 1981, Infection and immunity.