MER-29 (Triparanol) in the Control of Hypercholesterolæmia

There is a wide variety of auto-antibodies found in the serum of patients with Sjogren's syndrome. Table 1 gives the incidence of certain auto-antibodies in Sjogren's syndrome as found by Dr Deborah Doniach and myself in a recent survey. The rheumatoid factor was found in 82 %, and was present in the same proportion of cases without as with joint involvement, showing that the term 'rheumatoid factor' is misleading. The auto-immune complement-fixation test (A.l.C.F.) was done against salivary and lacrimal gland, liver and kidney. Tests for thyroid auto-antibodies were done as described by Hymans et al. (1961). The serum of patients with Sjogren's syndrome therefore contains both organ-specific as well as non-organ-specific auto-antibodies.

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