Improved method for computation of potentials in a realistic head shape model

The lead field analysis (LFA) algorithm, a new computational technique for the calculation of potentials on the surface of a realistic head shaped volume conductor model based on the boundary element method and the reciprocity theorem, is presented. The new algorithm, in comparison to the standard boundary element method, offers improved computational efficiency and lower storage requirements. It also yields more accurate surface potential results in the face of varying dipole source locations for a head shape boundary element model with a given number of nodes. Additionally, the algorithm results in quasi-analytic expressions of the derivatives of the surface potential with respect to the location of the sources, allowing the use of optimization techniques with better convergence properties. A set of simulations demonstrating the increased robustness of the LFA algorithm in the face of varying dipole source parameters is also described.<<ETX>>

[1]  Zhi Zhang,et al.  The effect of skull shape on single and multiple dipole source localizations , 1993, Proceedings of the 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Societ.

[2]  S. Sato,et al.  How well does a three-sphere model predict positions of dipoles in a realistically shaped head? , 1993, Electroencephalography and clinical neurophysiology.

[3]  D L Jewett,et al.  Insidious errors in dipole localization parameters at a single time-point due to model misspecification of number of shells. , 1993, Electroencephalography and clinical neurophysiology.

[4]  Kazutomo Yunokuchi,et al.  Tests of EEG localization accuracy using implanted sources in the human brain , 1991, Annals of neurology.

[5]  G. Stroink,et al.  Moving dipole inverse solutions using realistic torso models , 1991, IEEE Transactions on Biomedical Engineering.

[6]  M. Hallett,et al.  An improved method for localizing electric brain dipoles , 1990, IEEE Transactions on Biomedical Engineering.

[7]  T Musha,et al.  Effects of cavities on EEG dipole localization and their relations with surface electrode positions. , 1989, International journal of bio-medical computing.

[8]  James H. Kane,et al.  Reusable intrinsic sample point (RISP) algorithm for the efficient numerical integration of three dimensional curved boundary elements , 1989 .

[9]  A. van Oosterom,et al.  Source parameter estimation in inhomogeneous volume conductors of arbitrary shape , 1989, IEEE Transactions on Biomedical Engineering.

[10]  M. Hämäläinen,et al.  Realistic conductivity geometry model of the human head for interpretation of neuromagnetic data , 1989, IEEE Transactions on Biomedical Engineering.

[11]  Carlos Alberto Brebbia,et al.  Boundary Elements: An Introductory Course , 1989 .

[12]  S. Butler,et al.  Cortical generators of the CI component of the pattern-onset visual evoked potential. , 1987, Electroencephalography and clinical neurophysiology.

[13]  Toshimitsu Musha,et al.  Electric Dipole Tracing in the Brain by Means of the Boundary Element Method and Its Accuracy , 1987, IEEE Transactions on Biomedical Engineering.

[14]  M. Scherg,et al.  Evoked dipole source potentials of the human auditory cortex. , 1986, Electroencephalography and clinical neurophysiology.

[15]  J. P. Ary,et al.  Location of Sources of Evoked Scalp Potentials: Corrections for Skull and Scalp Thicknesses , 1981, IEEE Transactions on Biomedical Engineering.

[16]  P. Nunez,et al.  Electric fields of the brain , 1981 .

[17]  Anthony Sances,et al.  The Contributions of Intracerebral Currents to the EEG and Evoked Potentials , 1978, IEEE Transactions on Biomedical Engineering.

[18]  S. Butler,et al.  The localization of equivalent dipoles of EEG sources by the application of electrical field theory. , 1975, Electroencephalography and clinical neurophysiology.

[19]  R E Ideker,et al.  Eccentric dipole in a spherical medium: generalized expression for surface potentials. , 1973, IEEE transactions on bio-medical engineering.

[20]  M R Schneider,et al.  A multistage process for computing virtual dipolar sources of EEG discharges from surface information. , 1972, IEEE transactions on bio-medical engineering.

[21]  D. A. Driscoll,et al.  EEG electrode sensitivity--an application of reciprocity. , 1969, IEEE transactions on bio-medical engineering.

[22]  D. A. Driscoll,et al.  Current Distribution in the Brain From Surface Electrodes , 1968, Anesthesia and analgesia.