论文信息 - DNA Content and DNA-Based Centromeric Index of the 24 Human Chromosomes

DNA Content and DNA-Based Centromeric Index of the 24 Human Chromosomes

The chromosomes of two human males were identified by fluorescent banding, restained, and measured by scanning microscopy and computer analysis. The two variables, DNA content and DNA-based centromeric index, provided almost complete discrimination of chromosome types. Some chromosomes showed significant differences in DNA content between the men, and for one man two pairs of chromosomes showed significant differences between homologs.

[1] G. Ehrlich,et al. The Metabolic Basis Of Inherited Disease. , 1973 .

[2] M. Shaw,et al. Polymorphism of Human Constitutive Heterochromatin , 1971, Science.

[3] F. Ruddle,et al. Chromosome Polymorphism in American Negro and White Populations , 1971, Nature.

[4] G Gallus,et al. Improved computer chromosome analysis incorporating preprocessing and boundary analysis , 1970, Physics in medicine and biology.

[5] B. Mayall. DEOXYRIBONUCLEIC ACID CYTOPHOTOMETRY OF STAINED HUMAN LEUKOCYTES I. DIFFERENCES AMONG CELL TYPES , 1969, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[6] M. Mendelsohn,et al. COMPUTER‐ORIENTED ANALYSIS OF HUMAN CHROMOSOMES. II. INTEGRATED OPTICAL DENSITY AS A SINGLE PARAMETER FOR KARYOTYPE ANALYSIS * , 1969 .

[7] J. Prewitt,et al. Computer-oriented analysis of human chromosomes. I. Photometric estimation of DNA content. , 1966, Cytogenetics.

[8] P. Nowell,et al. Chromosome preparations of leukocytes cultured from human peripheral blood. , 1960, Experimental cell research.

[9] K PATAU,et al. The identification of individual chromosomes, especially in man. , 1960, American journal of human genetics.