Alcohol abuse and cigarette smoking are associated with global DNA hypermethylation: results from the German Investigation on Neurobiology in Alcoholism (GINA).

[1]  J. Kornhuber,et al.  Genetic variants of methionine metabolism and DNA methylation. , 2014, Epigenomics.

[2]  K. Hutchison,et al.  Alcohol and the methylome: design and analysis considerations for research using human samples. , 2013, Drug and alcohol dependence.

[3]  Teruhiko Yoshida,et al.  Association of dietary and genetic factors related to one‐carbon metabolism with global methylation level of leukocyte DNA , 2012, Cancer science.

[4]  A. Sakharkar,et al.  Epigenetics—Beyond the Genome in Alcoholism , 2012, Alcohol research : current reviews.

[5]  J. Kornhuber,et al.  Alterations of homocysteine serum levels during alcohol withdrawal are influenced by folate and riboflavin: results from the German Investigation on Neurobiology in Alcoholism (GINA). , 2012, Alcohol and alcoholism.

[6]  V. Hesselbrock,et al.  DNA methylation patterns in alcoholics and family controls. , 2012, World journal of gastrointestinal oncology.

[7]  P. Vokonas,et al.  Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis. , 2012, International journal of epidemiology.

[8]  P. Stover Polymorphisms in 1-Carbon Metabolism, Epigenetics and Folate-Related Pathologies , 2012, Lifestyle Genomics.

[9]  R. Cardarelli,et al.  Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood , 2011, Epigenetics.

[10]  J. Rinn,et al.  DNA methylation and epigenetic control of cellular differentiation , 2010, Cell cycle.

[11]  R. Peto,et al.  Alcohol and cause-specific mortality in Russia: a retrospective case–control study of 48 557 adult deaths , 2009, The Lancet.

[12]  S. Bleich,et al.  Homocysteine, Alcoholism and its Molecular Networks , 2009, Pharmacopsychiatry.

[13]  T. Teerlink,et al.  Global DNA methylation measured by liquid chromatography-tandem mass spectrometry: analytical technique, reference values and determinants in healthy subjects , 2007, Clinical chemistry and laboratory medicine.

[14]  K. Fliessbach,et al.  Homocysteine and Carotid Intima-Media Thickness in a German Population: Lack of Clinical Relevance , 2006, Stroke.

[15]  J. Kornhuber,et al.  Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism , 2006, Journal of Neural Transmission.

[16]  Trygve O Tollefsbol,et al.  The impact of metabolism on DNA methylation. , 2005, Human molecular genetics.

[17]  J. Kornhuber,et al.  Homocysteine associated genomic DNA hypermethylation in patients with chronic alcoholism , 2004, Journal of Neural Transmission.

[18]  C. Davis,et al.  DNA Methylation, Cancer Susceptibility, and Nutrient Interactions , 2004, Experimental biology and medicine.

[19]  S. Buyske,et al.  New 19 bp deletion polymorphism in intron‐1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy? , 2004, American journal of medical genetics. Part A.

[20]  H. Blom,et al.  Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects , 2002, European Journal of Human Genetics.

[21]  A. Chango,et al.  A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. , 2000, Molecular genetics and metabolism.

[22]  E. Rüther,et al.  Elevated homocysteine levels in alcohol withdrawal. , 2000, Alcohol and alcoholism.

[23]  M. Cravo,et al.  Hyperhomocysteinemia in chronic alcoholism: relations to folic acid and vitamins B(6) and B(12) status. , 2000, Nutrition.

[24]  F. Gabreëls,et al.  A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? , 1998, American journal of human genetics.

[25]  Alan D. Lopez,et al.  Alcohol consumption and mortality among middle-aged and elderly U.S. adults. , 1997, The New England journal of medicine.

[26]  P. Goyette,et al.  Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. , 1996, Human molecular genetics.

[27]  M. Tsai,et al.  High prevalence of a mutation in the cystathionine beta-synthase gene. , 1996, American journal of human genetics.

[28]  Shelly C. Lu,et al.  Alcohol, DNA Methylation, and Cancer , 2013, Alcohol research : current reviews.

[29]  P. Henke Heritability of Carotid Artery Atherosclerotic Lesions: An Ultrasound Study in 154 FamiliesMoskau S, Golla A, Grothe C, et al (Univ Hosp Bonn, Germany) Stroke 36:5–8, 2005§ , 2007 .

[30]  J. Aldenhoff,et al.  Development of a rating scale for quantitative measurement of the alcohol withdrawal syndrome , 2005, European Archives of Psychiatry and Clinical Neuroscience.

[31]  R. Matthews,et al.  A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase , 1995, Nature Genetics.

[32]  S. Mudd Disorders of transsulfuration , 1989 .