Analysis of EEG Signals Under Flash Stimulation for Migraine and Epileptic Patients

Migraine and epilepsy are both persistent disorders characterised by recurrent neurological attacks. Visual symptoms and hypersensitivity to light stimuli are frequent in migraine. Analysis of EEG signals under flash stimulation for migraine and epileptic patients is not a new method. But magnitude increasing under flash stimulation for migraine patients has not been studied yet. The aims of this study is the analysis of multichannel electroencephalogram (EEG) in migraine and epileptic patients by visual evoked potentials (VEP) and investigate the existence of magnitude increasing under flash stimulation for migraine patients. In this study as a method of flash stimuli at frequencies of 2, 4 and 6 Hz were applied to different migraine and epileptic patients under pain-free phase with the EEG recorded from 18 scalp electrodes, referred to the linked earlobes. We used AR parametric method to analyze and characterize EEG signals in migraine and epileptic patients. The variations in the EEG power spectra shapes were examined in order to obtain medical information. These power spectra were then used to compare the applied method in terms of their frequency resolution and the effects in determination of migraine and epilepsy. Global performance of the proposed methods was evaluated by means of the visual inspection of power spectral densities (PSDs). For the migraine patients, an increase in amplitude has observed at the beta bands of EEG signals under flash stimulation as compared to EEG signals without stimulation. As opposed to this, for epileptic patients, an increase in amplitude has observed at the alpha bands of EEG signals without flash stimulation. Meanwhile for the control groups, there is no change between EEG signals under flash stimulation and without flash stimulation.

[1]  Per Sidenius,et al.  Gender Differences in Epilepsy , 2005, Epilepsia.

[2]  S.M. Kay,et al.  Spectrum analysis—A modern perspective , 1981, Proceedings of the IEEE.

[3]  C. Panayiotopoulos Basilar migraine? seizures, and severe epileptic EEG abnormalities , 1980, Neurology.

[4]  D. Dalessio,et al.  Pattern‐Shift Visual Evoked Responses and EEG in Migraine , 1986, Headache.

[5]  B. Gurler,et al.  Flash visual evoked potentials and electroretinograms in migraine , 2001 .

[6]  N. Accornero,et al.  Impairment in Color Perception in Migraine With and Without Aura , 2007, Headache.

[7]  H. Akaike A new look at the statistical model identification , 1974 .

[8]  R. Lipton,et al.  Epilepsy and migraine , 2003, Epilepsy & Behavior.

[9]  F. Andermann,et al.  Basilar migraine, seizures, and severe epileptiform EEG abnormalities , 1978, Neurology.

[10]  Andrea Alberti,et al.  Electroencephalographic brain mapping and migraine , 2004, The Journal of Headache and Pain.

[11]  Petre Stoica,et al.  Introduction to spectral analysis , 1997 .

[12]  H. Adeli,et al.  Analysis of EEG records in an epileptic patient using wavelet transform , 2003, Journal of Neuroscience Methods.

[13]  P KISSEL,et al.  [Migraine and epilepsy]. , 1954, Revue medicale de Nancy.

[14]  Daniele Marinazzo,et al.  Visually evoked phase synchronization changes of alpha rhythm in migraine: correlations with clinical features. , 2005, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[15]  Vincenzo Guidetti,et al.  Clinical neurophysiology in childhood headache , 2004, The Journal of Headache and Pain.

[16]  John G. Proakis,et al.  Digital Signal Processing: Principles, Algorithms, and Applications , 1992 .

[17]  M. de Tommaso,et al.  Clinical Neurophysiology in Childhood Headache , 1999, Cephalalgia : an international journal of headache.

[18]  R Guerrini,et al.  Idiopathic Photosensitive Occipital Lobe Epilepsy , 1995, Epilepsia.

[19]  E Mariani,et al.  Pattern‐reversal Visual Evoked Potentials and EEG Correlations in Common Migraine Patients , 1988, Headache.

[20]  Daniele Marinazzo,et al.  Steady-state visual evoked potentials and phase synchronization in migraine patients. , 2004, Physical review letters.

[21]  John G. Proakis,et al.  Digital signal processing (3rd ed.): principles, algorithms, and applications , 1996 .

[22]  Paul K. Joseph,et al.  Analysis of EEG signals with and without reflexology using FFT and auto re- gressive modelling techniques , 2006 .

[23]  Robert R. Edwards,et al.  Coping with pain: Educational achievement moderates catastrophizing's effects on pain in scleroderma , 2004 .

[24]  R. Frigerio,et al.  Visual evoked potentials in migraine , 2004, Neurological Sciences.

[25]  Steven Kay,et al.  Modern Spectral Estimation: Theory and Application , 1988 .

[26]  G Bernardi,et al.  Multichannel visual evoked potentials in migraine. , 1995, Electroencephalography and clinical neurophysiology.

[27]  Marina de Tommaso,et al.  Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients , 2007, The Journal of Headache and Pain.

[28]  Mario Guazzelli Francomichele Puca in memoriam , 2004, The Journal of Headache and Pain.

[29]  M. Tommaso,et al.  EEG Features in Juvenile Migraine: Topographic Analysis of Spontaneous and Visual Evoked Brain Electrical Activity: A Comparison with Adult Migraine , 1994, Cephalalgia : an international journal of headache.

[30]  J HernándezGallego,et al.  Migraine and epilepsy , 1995 .

[31]  H. C. Diener,et al.  Visual Evoked Potentials in Migraine , 1985 .

[32]  C Bianco,et al.  Visual Evoked Potentials and Brainstem Auditory Evoked Potentials in Migraine and Transient Ischemic Attacks , 1985, Cephalalgia : an international journal of headache.

[33]  M. Drake,et al.  Visual and auditory evoked potentials in migraine. , 1990, Electromyography and clinical neurophysiology.