Same-single-cell analysis using the microfluidic biochip to reveal drug accumulation enhancement by an amphiphilic diblock copolymer drug formulation
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Paul C H Li | Paul C. H. Li | K. Letchford | H. Burt | Helen M Burt | Avid Khamenehfar | Kevin Letchford | Chung Ping Leon Wan | C. Wan | A. Khamenehfar
[1] K. Letchford,et al. A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes. , 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[2] W. Greco,et al. Cyclosporin A Is a Broad-Spectrum Multidrug Resistance Modulator , 2005, Clinical Cancer Research.
[3] H. Burt,et al. Methoxypolyethylene glycol-block-polycaprolactone diblock copolymers reduce P-glycoprotein efflux in the absence of a membrane fluidization effect while stimulating P-glycoprotein ATPase activity. , 2007, Journal of pharmaceutical sciences.
[4] R. Collander,et al. The Permeability of Nitella Cells to Non‐Eleetrolytes , 1954 .
[5] Alberto Guenzi,et al. Improvement of the Bioavailability of Colchicine in Rats by Co-administration of D-α-Tocopherol Polyethylene Glycol 1000 Succinate and a Polyethoxylated Derivative of 12-Hydroxy-Stearic Acid , 2002, Arzneimittelforschung.
[6] I. Hidalgo,et al. Evaluation of the MDR-MDCK cell line as a permeability screen for the blood-brain barrier. , 2005, International journal of pharmaceutics.
[7] K. Letchford,et al. Mixed molecular weight copolymer nanoparticles for the treatment of drug-resistant tumors: formulation development and cytotoxicity. , 2014, Journal of pharmaceutical sciences.
[8] Claus-Michael Lehr,et al. Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access. , 2010, Molecular pharmaceutics.
[9] Carol L. Williams,et al. Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia. , 1989, The Journal of biological chemistry.
[10] Ronald T. Borchardt,et al. Are MDCK Cells Transfected with the Human MRP2 Gene a Good Model of the Human Intestinal Mucosa? , 2004, Pharmaceutical Research.
[11] H. Burt,et al. Reversal of multidrug resistance by methoxypolyethylene glycol-block-polycaprolactone diblock copolymers through the inhibition of P-glycoprotein function. , 2009, Journal of pharmaceutical sciences.
[12] Paul C H Li,et al. A three-dimensional flow control concept for single-cell experiments on a microchip. 1. Cell selection, cell retention, cell culture, cell balancing, and cell scanning. , 2004, Analytical chemistry.
[13] Jochem Alsenz,et al. The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins. , 2003, Journal of pharmaceutical sciences.
[14] R. Liggins,et al. In vitro human plasma distribution of nanoparticulate paclitaxel is dependent on the physicochemical properties of poly(ethylene glycol)-block-poly(caprolactone) nanoparticles. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[15] Extraction of pure cellular fluorescence by cell scanning in a single-cell microchip. , 2005, Lab on a chip.
[16] K. Wasan,et al. Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells. , 2007, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
[17] A. Kabanov,et al. An essential relationship between ATP depletion and chemosensitizing activity of Pluronic block copolymers. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[18] D. B. Duignan,et al. A 96-well efflux assay to identify ABCG2 substrates using a stably transfected MDCK II cell line. , 2006, Molecular pharmaceutics.
[19] Grégori Gerebtzoff,et al. Enhancement of drug absorption by noncharged detergents through membrane and P-glycoprotein binding , 2006, Expert opinion on drug metabolism & toxicology.
[20] R. Liggins,et al. Enhanced cellular accumulation of a P-glycoprotein substrate, rhodamine-123, by Caco-2 cells using low molecular weight methoxypolyethylene glycol-block-polycaprolactone diblock copolymers. , 2002, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[21] M. Gottesman,et al. Drug resistance: still a daunting challenge to the successful treatment of AML. , 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[22] H. Burt,et al. Evidence for Modulation of P-glycoprotein-Mediated Efflux by Methoxypolyethylene Glycol-block-Polycaprolactone Amphiphilic Diblock Copolymers , 2004, Pharmaceutical Research.
[23] A. Mitra,et al. Influence of overexpression of efflux proteins on the function and gene expression of endogenous peptide transporters in MDR-transfected MDCKII cell lines. , 2013, International journal of pharmaceutics.
[24] K. Letchford,et al. The combined use of paclitaxel-loaded nanoparticles with a low-molecular-weight copolymer inhibitor of P-glycoprotein to overcome drug resistance , 2013, International journal of nanomedicine.
[25] J. Parker. Overcoming Multidrug Resistance in Cancer: An Update on the Clinical Strategy of Inhibiting P-Glycoprotein , 2003 .
[26] Ronald T Borchardt,et al. A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro. , 2002, Journal of pharmaceutical sciences.
[27] R. Liggins,et al. Synthesis and micellar characterization of short block length methoxy poly(ethylene glycol)-block-poly(caprolactone) diblock copolymers. , 2004, Colloids and surfaces. B, Biointerfaces.
[28] W. Sawyer,et al. Reversal of multidrug resistance by surfactants. , 1992, British journal of cancer.
[29] Feng Shen,et al. Study of flow behaviors on single-cell manipulation and shear stress reduction in microfluidic chips using computational fluid dynamics simulations. , 2014, Biomicrofluidics.
[30] Xiujun Li,et al. Microfluidic selection and retention of a single cardiac myocyte, on-chip dye loading, cell contraction by chemical stimulation, and quantitative fluorescent analysis of intracellular calcium. , 2005, Analytical chemistry.
[31] H. Burt,et al. P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: relationship between copolymer concentration and substrate hydrophobicity. , 2008, Molecular pharmaceutics.
[32] Xiujun Li,et al. Real‐time monitoring of intracellular calcium dynamic mobilization of a single cardiomyocyte in a microfluidic chip pertaining to drug discovery , 2007, Electrophoresis.
[33] W. Stein,et al. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. , 1997, Physiological reviews.
[34] James E Polli,et al. Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers. , 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[35] Yuan-Ping Shi,et al. Multifunctional Pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors. , 2011, Biomaterials.
[36] B. Hirst,et al. The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability. , 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[37] M. Chiao,et al. Increased accumulation and retention of micellar paclitaxel in drug-sensitive and P-glycoprotein-expressing cell lines following ultrasound exposure. , 2012, Ultrasound in medicine & biology.
[38] Paul C. H. Li. Microfluidic Lab-On-A-Chip for Chemical and Biological Analysis and Discovery , 2005 .
[39] Ying Zhu,et al. Multifunctional picoliter droplet manipulation platform and its application in single cell analysis. , 2011, Analytical chemistry.
[40] F. Van Bambeke,et al. ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions. , 2011, Current drug targets.
[41] Y. Shao,et al. Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein. , 1996, Biochimica et biophysica acta.
[42] Francisco Sanz-Rodríguez,et al. Fluorescent nanothermometers provide controlled plasmonic-mediated intracellular hyperthermia. , 2013, Nanomedicine.
[43] Paul C H Li,et al. Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip. , 2009, Integrative biology : quantitative biosciences from nano to macro.
[44] A. Mitra,et al. Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor. , 2007, International journal of pharmaceutics.
[45] F. Sharom. ABC multidrug transporters: structure, function and role in chemoresistance. , 2008, Pharmacogenomics.
[46] Paul C H Li,et al. A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells. , 2011, Lab on a chip.
[47] Dino Di Carlo,et al. Dynamic single-cell analysis for quantitative biology. , 2006, Analytical chemistry.
[48] Victor Ling,et al. Same-single-cell analysis for the study of drug efflux modulation of multidrug resistant cells using a microfluidic chip. , 2008, Analytical chemistry.