Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults

Summary Background  Vitamin D mediates immunomodulatory functions, and beneficial functions in allergic diseases have been suggested. Vitamin D receptor gene (VDR) polymorphisms are known but have not been studied in patients with atopic dermatitis (AD).

[1]  C. Loddenkemper,et al.  Vitamin D receptor activation improves allergen-triggered eczema in mice. , 2012, The Journal of investigative dermatology.

[2]  C. Ryan,et al.  Clinical and genetic predictors of response to narrowband ultraviolet B for the treatment of chronic plaque psoriasis , 2010, The British journal of dermatology.

[3]  T. Werfel,et al.  Innate immunity, allergy and atopic dermatitis , 2010, Current opinion in allergy and clinical immunology.

[4]  D. Leung,et al.  Vitamin D in atopic dermatitis, asthma and allergic diseases. , 2010, Immunology and allergy clinics of North America.

[5]  J. Brehm,et al.  Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. , 2010, The Journal of allergy and clinical immunology.

[6]  Y. Gong,et al.  Association study between vitamin D receptor gene polymorphisms and asthma in the chinese han population: a case-control study , 2009, BMC Medical Genetics.

[7]  C. Camargo,et al.  Randomized controlled trial of vitamin D supplementation for winter‐related atopic dermatitis in Boston: a pilot study , 2008, The British journal of dermatology.

[8]  D. Tamandl,et al.  Vitamin D3 down‐regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen‐associated molecular patterns , 2006, European journal of immunology.

[9]  M. Dallman,et al.  Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. , 2005, The Journal of clinical investigation.

[10]  R. Lea,et al.  VARIATION IN THE VITAMIN D RECEPTOR GENE IS ASSOCIATED WITH MULTIPLE SCLEROSIS IN AN AUSTRALIAN POPULATION , 2005, Journal of neurogenetics.

[11]  E. Silverman,et al.  Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. , 2004, American journal of respiratory and critical care medicine.

[12]  T. Hudson,et al.  Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy. , 2004, American journal of respiratory and critical care medicine.

[13]  P. Elias,et al.  Mice lacking 25OHD 1α-hydroxylase demonstrate decreased epidermal differentiation and barrier function , 2004, The Journal of Steroid Biochemistry and Molecular Biology.

[14]  H. Koeffler,et al.  Vitamin D receptor: no evidence for allele-specific mRNA stability in cells which are heterozygous for the Taq I restriction enzyme polymorphism. , 1997, Biochemical and biophysical research communications.