GNRH family genes contributed to gender-specific disparity of bladder cancer prognosis through exerting opposite regulatory roles between males and females

[1]  C. Lutz,et al.  Gender Differences in Urothelial Bladder Cancer: Effects of Natural Killer Lymphocyte Immunity , 2021, Journal of clinical medicine.

[2]  A. Schally,et al.  Expression of Luteinizing Hormone-Releasing Hormone (LHRH) and Type-I LHRH Receptor in Transitional Cell Carcinoma Type of Human Bladder Cancer , 2021, Molecules.

[3]  Yuquan Wei,et al.  Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode , 2020, Nature Communications.

[4]  A. Kamat,et al.  Sex Differences in Bladder Cancer Immunobiology and Outcomes: A Collaborative Review with Implications for Treatment. , 2020, European urology oncology.

[5]  A. Jemal,et al.  Cancer statistics, 2020 , 2020, CA: a cancer journal for clinicians.

[6]  G. Baggio,et al.  Spotlight on gender-specific disparities in bladder cancer , 2019, Urologia.

[7]  L. Kiemeney,et al.  Bladder cancer survival: Women only fare worse in the first two years after diagnosis. , 2019, Urologic oncology.

[8]  R. Bourgon,et al.  TGF-β attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells , 2018, Nature.

[9]  Jacques Ferlay,et al.  Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends. , 2017, European urology.

[10]  S. Shariat,et al.  Female with bladder cancer: what and why is there a difference? , 2016, Translational andrology and urology.

[11]  Erich P Huang,et al.  RECIST 1.1-Update and clarification: From the RECIST committee. , 2016, European journal of cancer.

[12]  P. Limonta,et al.  GnRH and GnRH receptors in the pathophysiology of the human female reproductive system. , 2016, Human reproduction update.

[13]  Y. Lotan,et al.  Gender and Bladder Cancer: A Collaborative Review of Etiology, Biology, and Outcomes. , 2016, European urology.

[14]  J. Mesirov,et al.  The Molecular Signatures Database Hallmark Gene Set Collection , 2015 .

[15]  Davide Heller,et al.  STRING v10: protein–protein interaction networks, integrated over the tree of life , 2014, Nucleic Acids Res..

[16]  A. Masson-Lecomte,et al.  Gender-specific differences in clinicopathologic outcomes following radical cystectomy: an international multi-institutional study of more than 8000 patients. , 2014, European urology.

[17]  Y. Lotan,et al.  Female gender is associated with a worse survival after radical cystectomy for urothelial carcinoma of the bladder: a competing risk analysis. , 2014, Urology.

[18]  C. Lyttle,et al.  Sex disparities in diagnosis of bladder cancer after initial presentation with hematuria: A nationwide claims‐based investigation , 2014, Cancer.

[19]  L. Häberle,et al.  Female sex is an independent risk factor for reduced overall survival in bladder cancer patients treated by transurethral resection and radio- or radiochemotherapy , 2013, World Journal of Urology.

[20]  Justin Guinney,et al.  GSVA: gene set variation analysis for microarray and RNA-Seq data , 2013, BMC Bioinformatics.

[21]  R. Sylvester,et al.  Female gender and carcinoma in situ in the prostatic urethra are prognostic factors for recurrence, progression, and disease-specific mortality in T1G3 bladder cancer patients treated with bacillus Calmette-Guérin. , 2012, European urology.

[22]  E. Lundberg,et al.  Towards a knowledge-based Human Protein Atlas , 2010, Nature Biotechnology.

[23]  Gary D. Bader,et al.  The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function , 2010, Nucleic Acids Res..

[24]  E. Messing,et al.  Sex and racial differences in bladder cancer presentation and mortality in the US , 2009, Cancer.

[25]  Cheryl T. Lee,et al.  Patterns of hematuria referral to urologists: does a gender disparity exist? , 2008, Urology.

[26]  Jill P. Mesirov,et al.  GSEA-P: a desktop application for Gene Set Enrichment Analysis , 2007, Bioinform..

[27]  G. Sonpavde,et al.  Expression of estrogen receptors‐α and ‐β in bladder cancer cell lines and human bladder tumor tissue , 2006 .

[28]  S. Boorjian,et al.  Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer. , 2004, Urology.

[29]  M. Motta,et al.  The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans , 2003, Frontiers in Neuroendocrinology.

[30]  R. Sharpe,et al.  Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist , 1985, Nature.