Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system.
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Harinder Singh | D. Lancki | J. Pongubala | Harinder Singh | Peter Laslo | Jagan M R Pongubala | David W Lancki | P. Laslo
[1] Pu Zhang,et al. Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element , 2005, Molecular and Cellular Biology.
[2] Mark J. Murphy,et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. , 2004, Genes & development.
[3] M. Busslinger,et al. Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. , 2008, Immunity.
[4] D. Bartel,et al. MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.
[5] A. Cumano,et al. Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development , 2003, Nature Immunology.
[6] S. Orkin,et al. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. , 1991, Genes & development.
[7] M. Busslinger,et al. Distinct Promoters Mediate the Regulation of Ebf1 Gene Expression by Interleukin-7 and Pax5 , 2006, Molecular and Cellular Biology.
[8] A. Burgess,et al. Mice Lacking Three Myeloid Colony-Stimulating Factors (G-CSF, GM-CSF, and M-CSF) Still Produce Macrophages and Granulocytes and Mount an Inflammatory Response in a Sterile Model of Peritonitis1 , 2007, The Journal of Immunology.
[9] F. Morlé,et al. Functional Cross-Antagonism between Transcription Factors FLI-1 and EKLF , 2003, Molecular and Cellular Biology.
[10] E. Bertolino,et al. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5 , 2008, Nature Immunology.
[11] M. Sigvardsson,et al. Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development. , 2005, Blood.
[12] M. Kondo,et al. IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF , 2005, The Journal of experimental medicine.
[13] Harinder Singh,et al. Assembling a gene regulatory network for specification of the B cell fate. , 2004, Developmental cell.
[14] I. Weissman,et al. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages , 2000, Nature.
[15] R. Gerstein,et al. The Earliest Step in B Lineage Differentiation from Common Lymphoid Progenitors Is Critically Dependent upon Interleukin 7 , 2002, The Journal of experimental medicine.
[16] P. Lásló,et al. Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates , 2006, Cell.
[17] Harinder Singh,et al. Contingent gene regulatory networks and B cell fate specification. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[18] M. Busslinger,et al. Reversion of B Cell Commitment upon Loss of Pax5 Expression , 2002, Science.
[19] E. Wagner,et al. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5 BSAP , 1994, Cell.
[20] I. Weissman,et al. Purification and characterization of mouse hematopoietic stem cells. , 1988, Science.
[21] M. Busslinger,et al. Analysis of Notch1 Function by In Vitro T Cell Differentiation of Pax5 Mutant Lymphoid Progenitors1 , 2004, The Journal of Immunology.
[22] E. Scott,et al. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. , 1994, Science.
[23] S. Ng,et al. Early hematopoietic lineage restrictions directed by Ikaros , 2006, Nature Immunology.
[24] D. Bartel,et al. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs , 2004, Nature Reviews Genetics.
[25] S. Jacobsen,et al. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. , 2002, Immunity.
[26] M. Busslinger,et al. Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. , 2004, Genes & development.
[27] S. Orkin,et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells , 2004, Nature.
[28] P. Pandolfi,et al. Regulation of B Versus T Lymphoid Lineage Fate Decision by the Proto-Oncogene LRF , 2007, Science.
[29] S. Jacobsen,et al. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. , 2001, Immunity.
[30] Daniel G Tenen,et al. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. , 2006, Genes & development.
[31] Alessandro Fatica,et al. A Minicircuitry Comprised of MicroRNA-223 and Transcription Factors NFI-A and C/EBPα Regulates Human Granulopoiesis , 2005, Cell.
[32] Hiroshi Kawamoto,et al. Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. , 2004, Immunity.
[33] S. Orkin,et al. Transcription factor GATA‐1 in megakaryocyte development , 1998, Stem cells.
[34] K. Anderson,et al. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells. , 2008, Blood.
[35] T. Graf,et al. B young again. , 2008, Immunity.
[36] A. Bhandoola,et al. The earliest thymic progenitors for T cells possess myeloid lineage potential , 2008, Nature.
[37] R. Plasterk,et al. The diverse functions of microRNAs in animal development and disease. , 2006, Developmental cell.
[38] M. Busslinger,et al. Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. , 2006, Immunity.
[39] Carlo M. Croce,et al. MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation , 2007, Nature Cell Biology.
[40] S. Akira,et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. , 2006, Immunity.
[41] A. Cumano,et al. Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors , 2005, The Journal of experimental medicine.
[42] Lina A. Thoren,et al. Identification of Flt3+ Lympho-Myeloid Stem Cells Lacking Erythro-Megakaryocytic Potential A Revised Road Map for Adult Blood Lineage Commitment , 2005, Cell.
[43] H. Singh,et al. PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates. , 1999, Cold Spring Harbor symposia on quantitative biology.
[44] N. Rekhtman,et al. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. , 1999, Genes & development.
[45] D. Tenen,et al. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[46] K. Akashi,et al. C/EBPβ is required for 'emergency' granulopoiesis , 2006, Nature Immunology.
[47] T. Graf,et al. Stepwise Reprogramming of B Cells into Macrophages , 2004, Cell.
[48] H. Weintraub,et al. The helix-loop-helix gene E2A is required for B cell formation , 1994, Cell.
[49] Ian Krop,et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements , 1994, Cell.
[51] Irving L. Weissman,et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.
[52] Min Ye,et al. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. , 2002, Developmental cell.
[53] R. Grosschedl,et al. Failure of B-cell differentiation in mice lacking the transcription factor EBF , 1995, Nature.
[54] Michael T. McManus,et al. Gene silencing in mammals by small interfering RNAs , 2002, Nature Reviews Genetics.
[55] Marius Wernig,et al. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency , 2008, Cell.
[56] Ellen V Rothenberg,et al. Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals. , 2007, Immunity.
[57] T. Ikawa,et al. Adult T-cell progenitors retain myeloid potential , 2008, Nature.
[58] G. Cheng,et al. Deregulated expression of the PU.1 transcription factor blocks murine erythroleukemia cell terminal differentiation , 1997, Oncogene.
[59] S. Orkin,et al. Transcriptional regulation of erythropoiesis: an affair involving multiple partners , 2002, Oncogene.
[60] Stuart H. Orkin,et al. Diversification of haematopoietic stem cells to specific lineages , 2000, Nature Reviews Genetics.
[61] H. Singh,et al. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. , 2000, Science.
[62] Stephen L. Nutt,et al. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 , 1999, Nature.
[63] B. Kee,et al. Early B Cell Factor Promotes B Lymphopoiesis with Reduced Interleukin 7 Responsiveness in the Absence of E2A , 2004, The Journal of experimental medicine.
[64] M. Busslinger,et al. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors , 1999, Nature.
[65] Pu Zhang,et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. , 2004, Immunity.
[66] L. Zon,et al. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology , 2008, Cell.
[67] T. Graf,et al. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. , 1995, Genes & development.
[68] W. Pear,et al. Regulation of lymphoid development, differentiation, and function by the Notch pathway. , 2005, Annual review of immunology.
[69] S. Orkin,et al. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. , 2000, Blood.
[70] C. Croce,et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[71] T. Graf,et al. Determinants of lymphoid-myeloid lineage diversification. , 2006, Annual review of immunology.
[72] A. Fatica,et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation , 2007, Proceedings of the National Academy of Sciences.
[73] T. Graf. Immunology: Blood lines redrawn , 2008, Nature.
[74] Ellen V Rothenberg,et al. Cell lineage regulators in B and T cell development , 2007, Nature Immunology.
[75] S. Nutt,et al. The transcriptional regulation of B cell lineage commitment. , 2007, Immunity.
[76] Richard Dahl,et al. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor , 2003, Nature Immunology.
[77] Ignacio A. Demarco,et al. Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros , 2008, Nature Immunology.
[78] Nicola K. Wilson,et al. A Two-Step, PU.1-Dependent Mechanism for Developmentally Regulated Chromatin Remodeling and Transcription of the c-fms Gene , 2006, Molecular and Cellular Biology.
[79] K. Akashi,et al. Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. , 2007, Cell stem cell.
[80] I. Mårtensson,et al. Complementary Signaling through flt3 and Interleukin-7 Receptor α Is Indispensable for Fetal and Adult B Cell Genesis , 2003, The Journal of experimental medicine.
[81] S. Goff,et al. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. , 1995, Immunity.
[82] R. Grosschedl,et al. Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. , 1999, Immunity.