Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis

[1]  Joachim Wegener,et al.  Electrical wound-healing assay for cells in vitro. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[2]  W. Birchmeier,et al.  Met, metastasis, motility and more , 2003, Nature Reviews Molecular Cell Biology.

[3]  G. Guy,et al.  Tyrosine Phosphorylation of Sprouty2 Enhances Its Interaction with c-Cbl and Is Crucial for Its Function* , 2003, Journal of Biological Chemistry.

[4]  G. Guy,et al.  Sprouty: how does the branch manager work? , 2003, Journal of Cell Science.

[5]  M. Shibuya,et al.  Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1 , 2003, Nature Cell Biology.

[6]  G. V. Vande Woude,et al.  Endosomal dynamics of Met determine signaling output. , 2003, Molecular biology of the cell.

[7]  V. Litvak,et al.  Sprouty Fine-Tunes EGF Signaling through Interlinked Positive and Negative Feedback Loops , 2003, Current Biology.

[8]  D. Bar-Sagi,et al.  hSpry2 Is Targeted to the Ubiquitin-Dependent Proteasome Pathway by c-Cbl , 2003, Current Biology.

[9]  N. Sreejayan,et al.  Protein-tyrosine Phosphatase-1B (PTP1B) Mediates the Anti-migratory Actions of Sprouty* , 2003, The Journal of Biological Chemistry.

[10]  E. Nishida,et al.  Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway , 2002, Nature Cell Biology.

[11]  Boon Chuan Low,et al.  Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling , 2002, The EMBO journal.

[12]  D. Bar-Sagi,et al.  The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[13]  Giorgio F. Gilestro,et al.  The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met , 2002, Nature.

[14]  G. Guy,et al.  Sprouty2 Inhibits the Ras/MAP Kinase Pathway by Inhibiting the Activation of Raf* , 2002, The Journal of Biological Chemistry.

[15]  Jonathan D. Licht,et al.  Mammalian Sprouty Proteins Inhibit Cell Growth and Differentiation by Preventing Ras Activation* , 2001, The Journal of Biological Chemistry.

[16]  P. Itäranta,et al.  Expression of Sprouty genes 1, 2 and 4 during mouse organogenesis , 2001, Mechanisms of Development.

[17]  H. Band,et al.  Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. , 2001, Molecular cell.

[18]  M. Kohno,et al.  ERK pathway positively regulates the expression of Sprouty genes. , 2001, Biochemical and biophysical research communications.

[19]  G. Woude,et al.  Down-regulation of MET, the receptor for hepatocyte growth factor , 2001, Oncogene.

[20]  J. Thiery,et al.  Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis , 2001, Mechanisms of Development.

[21]  G. Christofori,et al.  Mammalian Sprouty-1 and -2 Are Membrane-Anchored Phosphoprotein Inhibitors of Growth Factor Signaling in Endothelial Cells , 2001, The Journal of cell biology.

[22]  M. Krasnow,et al.  Inhibition of Angiogenesis by a Mouse Sprouty Protein* , 2001, The Journal of Biological Chemistry.

[23]  R. Klausner,et al.  The von Hippel-Lindau Tumor Suppressor Gene Inhibits Hepatocyte Growth Factor/Scatter Factor-Induced Invasion and Branching Morphogenesis in Renal Carcinoma Cells , 1999, Molecular and Cellular Biology.

[24]  Matthew Freeman,et al.  Sprouty, an Intracellular Inhibitor of Ras Signaling , 1999, Cell.

[25]  J. Thiery,et al.  Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo , 1999, Mechanisms of Development.

[26]  D. Warburton,et al.  Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis , 1999, Current Biology.

[27]  N. Hacohen,et al.  sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways , 1998, Cell.

[28]  S. Ōmura,et al.  Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway , 1997, Molecular and cellular biology.

[29]  G. V. Vande Woude,et al.  Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network , 1996, Molecular and cellular biology.

[30]  A. Malik,et al.  Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[31]  I. Giaever,et al.  Micromotion of mammalian cells measured electrically. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[32]  C. Miranti.  Application of cell adhesion to study signaling networks. , 2002, Methods in cell biology.