Characterization, mechanical, and antibacterial properties of nanofibers derived from olive leaf, fumitory, and terebinth extracts

In this study, nanofiber structures were obtained with convenient polymers (PVA [polyvinyl alcohol] and PCL [poly o-caprolactone]) derived from the herbal extracts of olive leaves, fumitory, and terebinth plants. Optimum nanofiber structures were identified by measuring viscosity and conductivity values and performing morphological analysis, characterization, and mechanical tests of the prepared solutions. The potential use for wound healing at the most efficient level was determined as a result of antibacterial analysis of the structures obtained. APT (PVA/terebinth) and BFO (PCL/fumitory) nanofibers had the thinnest diameter range and the highest strength values. In terms of the determination of antibacterial effects, nanofiber structures of all 3 plant species proved to be effective against bacteria. The greatest effect was observed against Escherichia coli in the nanofiber structure containing olive leaves, with a zone diameter of 32 mm. In addition, APT and BFO nanofibers had the highest values of thinness and strength. In these 2 samples, using BFO against Staphylococcus aureus and APT against Candida albicans increased their areas of activity. In the literature review, no study was available about obtaining nanofibers, especially from fumitory and terebinth plants. This study aimed to increase knowledge on obtaining nanofiber structures, including various polymers derived from olive leaves, fumitory, and terebinth plants.

[1]  G. Acik,et al.  Synthesis, properties and biodegradability of cross-linked amphiphilic Poly(vinyl acrylate)-Poly(tert-butyl acrylate)s by photo-initiated radical polymerization , 2020 .

[2]  Dietmar W. Hutmacher,et al.  Degradation mechanisms of polycaprolactone in the context of chemistry, geometry and environment , 2019, Progress in Polymer Science.

[3]  H. Avci,et al.  Synergistic effects of plant extracts and polymers on structural and antibacterial properties for wound healing , 2018, Polymer Bulletin.

[4]  C. Ng,et al.  Application of polyvinyl alcohol (PVA) in cement-based composite materials: A review of its engineering properties and microstructure behavior , 2016 .

[5]  S. Bahrami,et al.  Electrospun curcumin loaded poly(ε-caprolactone)/gum tragacanth nanofibers for biomedical application. , 2016, International journal of biological macromolecules.

[6]  Subbu S. Venkatraman,et al.  Polycaprolactone-based biomaterials for tissue engineering and drug delivery: Current scenario and challenges , 2016 .

[7]  G. Basal,et al.  Bioactive Sheath/Core nanofibers containing olive leaf extract , 2016, Microscopy research and technique.

[8]  Dirk Herrmann,et al.  An Introduction To Electrospinning And Nanofibers , 2016 .

[9]  V. R. G. Dev,et al.  Electrospun herbal nanofibrous wound dressings for skin tissue engineering , 2015 .

[10]  O. Bayraktar,et al.  Olive leaf extract as a crosslinking agent for the preparation of electrospun zein fibers , 2015 .

[11]  K. A. Sekak,et al.  Characteristics of Electrospun PVA-Aloe vera Nanofibres Produced via Electrospinning , 2014 .

[12]  Burcu Özdamar Immobilization of olive leaf extract on chitosan nanoparticles and investigation of their effects on cancer cell lines , 2014 .

[13]  N. Petkova,et al.  Antioxidant activities and phenolic compounds in Bulgarian Fumaria species , 2014 .

[14]  R. Rahimi,et al.  Five Pistacia species (P. vera, P. atlantica, P. terebinthus, P. khinjuk, and P. lentiscus): A Review of Their Traditional Uses, Phytochemistry, and Pharmacology , 2013, TheScientificWorldJournal.

[15]  H. Avci,et al.  Preparation of antibacterial PVA and PEO nanofibers containing Lawsonia Inermis (henna) leaf extracts , 2013, Journal of biomaterials science. Polymer edition.

[16]  M. Prabhakaran,et al.  Tissue engineered plant extracts as nanofibrous wound dressing. , 2013, Biomaterials.

[17]  Farooq Anwar,et al.  Valuable Nutrients and Functional Bioactives in Different Parts of Olive (Olea europaea L.)—A Review , 2012, International journal of molecular sciences.

[18]  V. Gökmen,et al.  Changes in oxidative stability, antioxidant capacity and phytochemical composition of Pistacia terebinthus oil with roasting. , 2011, Food chemistry.

[19]  C. Call The study of electrospun nanofibers and the application of electrospinning in engineering education , 2009 .

[20]  D. Carroll,et al.  The mechanical properties of individual, electrospun fibrinogen fibers. , 2009, Biomaterials.

[21]  O. Bayraktar,et al.  Isolation of polyphenols from the extracts of olive leaves (Olea europaea L.) by adsorption on silk fibroin , 2008 .

[22]  Tatjana Kadifkova Panovska,et al.  Antioxidant and antimicrobial activities of the Pistacia lentiscus and Pistacia atlantica extracts , 2008 .

[23]  Lovasoa Rakotondramasy-Rabesiaka,et al.  Solid-liquid extraction of protopine from Fumaria officinalis L.- : Analysis determination, kinetic reaction and model building , 2007 .

[24]  O. Bayraktar,et al.  Adsorption of olive leaf (Olea europaea L.) antioxidants on silk fibroin. , 2007, Journal of agricultural and food chemistry.

[25]  M. Öztürk,et al.  A new flavone from antioxidant extracts of Pistacia terebinthus , 2007 .

[26]  A. Ranalli,et al.  Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.). , 2006, Journal of agricultural and food chemistry.

[27]  S. Shivkumar,et al.  Effect of molecular weight on fibrous PVA produced by electrospinning , 2004 .

[28]  M. Recio,et al.  Anti-Inflammatory Triterpenes from Pistacia terebinthus Galls , 2002, Planta medica.

[29]  Ö. Erdoğrul Antibacterial Activities of Some Plant Extracts Used in Folk Medicine , 2002 .

[30]  M. Recio,et al.  On the anti-inflammatory and anti-phospholipase A(2) activity of extracts from lanostane-rich species. , 2000, Journal of ethnopharmacology.