论文信息 - High-count-rate multichannel TCSPC for optical tomography

High-count-rate multichannel TCSPC for optical tomography

An improved Time-Correlated Single Photon Counting (TCSPC) technique features high count rate, low differential nonlinearity and multi-detector capability. The system has four completely parallel TCSPC channels and achieves an effective overall count rate of 20 MHz. By an active routing technique, up to eight detectors can be connected to each of the TCSPC channels. We used the system to record optical mammograms after pulsed laser illumination at different wavelengths and projection angles.

[1] F Gao,et al. Simultaneous mapping of absorption and scattering coefficients from a three-dimensional model of time-resolved optical tomography. , 2000, Applied optics.

[2] D. Kopans,et al. Digital tomosynthesis in breast imaging. , 1997, Radiology.

[3] P M Schlag,et al. Development of a time-domain optical mammograph and first in vivo applications. , 1999, Applied optics.

[4] K D Paulsen,et al. Spectroscopic diffuse optical tomography for the quantitative assessment of hemoglobin concentration and oxygen saturation in breast tissue. , 1999, Applied optics.

[5] B. Wilson,et al. Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. , 1989, Applied optics.

[6] S. Arridge. Optical tomography in medical imaging , 1999 .

[7] J. Melissen,et al. Tomographic image reconstruction from optical projections in light-diffusing media. , 1997, Applied optics.