论文信息 - Studies on the metabolism of tissue proteins. II. Influence of x-irradiation and starvation on the metabolism of collagen.

Studies on the metabolism of tissue proteins. II. Influence of x-irradiation and starvation on the metabolism of collagen.

Rats were injected with proline-U-C/sup 14/ and exposed to total-body x irradiation at various time-intervals thereafter. Proline and hydroxyproline were isolated from collagen of various organs as well as from sub-fractions of skin collagen and their specific activity determined. From the changes in specific activity of proline and hydroxyproline observed after exposure it is postulated that more metabolically-active collagen is degraded and that the conversion of soluble to insoluble collagen is partially inhibited after irradiation. (auth)

L. Hempelmann | G. Gerber | K. Altman

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