Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome.
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Stuart M Haslam | Anne Dell | Klaus Ley | James C Paulson | Parastoo Azadi | K. Ley | P. Azadi | A. Dell | J. Paulson | A. Antonopoulos | S. Haslam | R. Sonon | C. Lefort | Cory D Rillahan | Aristotelis Antonopoulos | Craig T Lefort | Roberto Sonon | Cory D. Rillahan | Craig T. Lefort
[1] T. A. Fritz,et al. Disaccharide uptake and priming in animal cells: inhibition of sialyl Lewis X by acetylated Gal beta 1-->4GlcNAc beta-O-naphthalenemethanol. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[2] G J Davies,et al. Glycosyltransferases: structures, functions, and mechanisms. , 2008, Annual review of biochemistry.
[3] J. Marth,et al. Immune regulation by the ST6Gal sialyltransferase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[4] P. Stanley,et al. Two Chinese hamster ovary glycosylation mutants affected in the conversion of GDP-mannose to GDP-fucose. , 1986, Archives of biochemistry and biophysics.
[5] J. Marth,et al. ST6Gal-I Restrains CD22-Dependent Antigen Receptor Endocytosis and Shp-1 Recruitment in Normal and Pathogenic Immune Signaling , 2006, Molecular and Cellular Biology.
[6] Syr Hui,et al. US Patent Application , 2013 .
[7] J. Paulson,et al. Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking , 2005, Nature chemical biology.
[8] J. Esko,et al. A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells. , 2003, Cancer research.
[9] C. Bertozzi,et al. Expanding the Diversity of Unnatural Cell‐Surface Sialic Acids , 2003, Chembiochem : a European journal of chemical biology.
[10] Shilpa A. Patil,et al. Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation , 2011, The Journal of Biological Chemistry.
[11] J. Marth,et al. The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis. , 2000, Immunity.
[12] T. Kupper,et al. Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen. , 2003, The Journal of clinical investigation.
[13] M. Pawlita,et al. Evidence for efficient uptake and incorporation of sialic acid by eukaryotic cells. , 2001, European journal of biochemistry.
[14] L. Curtiss,et al. Disruption of tissue-specific fucosyltransferase VII, an enzyme necessary for selectin ligand synthesis, suppresses atherosclerosis in mice. , 2009, The American journal of pathology.
[15] K. Ley,et al. Induction of LFA‐1‐Dependent Neutrophil Rolling on ICAM‐1 by Engagement of E‐Selectin , 2006, Microcirculation.
[16] Luzheng Liu,et al. Skin-Homing Receptors on Effector Leukocytes Are Differentially Sensitive to Glyco-Metabolic Antagonism in Allergic Contact Dermatitis1 , 2007, The Journal of Immunology.
[17] J. Marth,et al. A genetic approach to Mammalian glycan function. , 2003, Annual review of biochemistry.
[18] A. Fisher,et al. Crystal structures of Pasteurella multocida sialyltransferase complexes with acceptor and donor analogues reveal substrate binding sites and catalytic mechanism. , 2007, Biochemistry.
[19] S. Nishimura,et al. An efficient approach to the discovery of potent inhibitors against glycosyltransferases. , 2010, Journal of medicinal chemistry.
[20] Chi‐Huey Wong,et al. A New Method for the Synthesis of Fluoro-Carbohydrates and Glycosides Using Selectfluor , 1997 .
[21] A. Daugherty,et al. &agr;(1,3)Fucosyltransferases FucT-IV and FucT-VII Control Susceptibility to Atherosclerosis in Apolipoprotein E−/− Mice , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[22] Steven J Brown,et al. High-throughput screening for inhibitors of sialyl- and fucosyltransferases. , 2011, Angewandte Chemie.
[23] M. Pawlita,et al. UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation. , 1999, Science.
[24] Sriram Neelamegham,et al. Systems‐level studies of glycosyltransferase gene expression and enzyme activity that are associated with the selectin binding function of human leukocytes , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[25] Andrew G. Watts,et al. Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog , 2004, Nature Structural &Molecular Biology.
[26] S. Ley,et al. Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases. , 2000, Bioorganic & medicinal chemistry.
[27] C. Wong,et al. A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase. , 1997, Bioorganic & medicinal chemistry.
[28] A. Helenius,et al. Essentials of Glycobiology, A. Varki, R. Cummings, J. Esko, H. Freeze, G. Hart, J. Marth. Cold Spring Harbor Laboratory Press, Cold Spring Harbor NY (1999), 668 pp. $95.00 , 2000 .
[30] D. Vocadlo,et al. Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells , 2011, Nature chemical biology.
[31] C. Gleissner,et al. Glycosylation in immune cell trafficking , 2009, Immunological reviews.
[32] W. Miller,et al. Inhibition of CMP-sialic acid transport into Golgi vesicles by nucleoside monophosphates. , 2001, Biochemistry.
[33] Klaus Ley,et al. Monocyte-endothelial cell interactions in the development of atherosclerosis. , 2008, Trends in cardiovascular medicine.
[34] J. L. Goodman,et al. A cloned CD15s‐negative variant of HL60 cells is deficient in expression of FUT7 and does not adhere to cytokine‐stimulated endothelial cells , 1999, European journal of haematology.
[35] J. Lowe,et al. Glycan-dependent leukocyte adhesion and recruitment in inflammation. , 2003, Current opinion in cell biology.
[36] K. Yarema,et al. Metabolic oligosaccharide engineering: perspectives, applications, and future directions. , 2007, Molecular bioSystems.
[37] J. Lowe,et al. Fucose: biosynthesis and biological function in mammals. , 2003, Glycobiology.
[38] R. Hill,et al. Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences. , 1979, The Journal of biological chemistry.
[40] S. Walker,et al. Discovery of O-GlcNAc transferase inhibitors. , 2005, Journal of the American Chemical Society.
[41] C. Glass,et al. A Disaccharide-Based Inhibitor of Glycosylation Attenuates Metastatic Tumor Cell Dissemination , 2006, Clinical Cancer Research.
[42] F. Feng,et al. Glycomics for drug discovery: metabolic perturbation in androgen-independent prostate cancer cells induced by unnatural hexosamine mimics. , 2012, Angewandte Chemie.
[43] W. Reutter,et al. A Bifunctional Enzyme Catalyzes the First Two Steps in N-Acetylneuraminic Acid Biosynthesis of Rat Liver , 1997, The Journal of Biological Chemistry.
[44] R. Cummings,et al. Binding of Glycosulfopeptides to P-selectin Requires Stereospecific Contributions of Individual Tyrosine Sulfate and Sugar Residues* , 2000, The Journal of Biological Chemistry.
[45] J. Blanchard,et al. UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase. , 2010, Journal of the American Chemical Society.
[46] M. Cantz,et al. Defective lysosomal release of glycoprotein-derived sialic acid in fibroblasts from patients with sialic acid storage disease. , 1988, The Biochemical journal.
[47] S. Walker,et al. A strategy to discover inhibitors of O-linked glycosylation. , 2008, Journal of the American Chemical Society.
[48] Petr Malý,et al. The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis , 1996, Cell.
[49] Chi‐Huey Wong,et al. A Potent and Highly Selective Inhibitor of Human α-1,3-Fucosyltransferase via Click Chemistry , 2003 .
[50] Hisashi Narimatsu,et al. CD15 Expression in Mature Granulocytes Is Determined by α1,3-Fucosyltransferase IX, but in Promyelocytes and Monocytes by α1,3-Fucosyltransferase IV* , 2001, The Journal of Biological Chemistry.
[51] Carolyn R. Bertozzi,et al. Essentials of Glycobiology , 1999 .
[52] R. Kumar,et al. Molecular Cloning of Human GDP-mannose 4,6-Dehydratase and Reconstitution of GDP-fucose Biosynthesis in Vitro * , 1998, The Journal of Biological Chemistry.
[53] Ajit Varki,et al. Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins , 2007, Nature.