Cysteine chloromethyl and diazomethyl ketone derivatives with potent anti-leukemic activity.

[1]  F. Uckun,et al.  Rational Design and Synthesis of a Novel Anti-leukemic Agent Targeting Bruton′s Tyrosine Kinase (BTK), LFM-A13 [α-Cyano-β-Hydroxy-β-Methyl-N-(2,5-Dibromophenyl)Propenamide]* , 1999, The Journal of Biological Chemistry.

[2]  N. Heerema,et al.  Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation. , 1998, Blood.

[3]  H. Sather,et al.  Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy. , 1998, The New England journal of medicine.

[4]  X. P. Liu,et al.  4-(3'-Bromo-4'hydroxylphenyl)-amino-6,7-dimethoxyquinazoline: a novel quinazoline derivative with potent cytotoxic activity against human glioblastoma cells. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

[5]  H. Sather,et al.  Clinical features and treatment outcome of children with myeloid antigen positive acute lymphoblastic leukemia: a report from the Children's Cancer Group. , 1997, Blood.

[6]  R. Rando,et al.  Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease. , 1996, Biochemistry.

[7]  A. Burkhardt,et al.  Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases , 1995, Science.

[8]  F. Uckun,et al.  Sensitivity of primary clonogenic blasts from acute lymphoblastic leukemia patients to an activated cyclophosphamide, viz., mafosfamide. , 1994, Leukemia & lymphoma.

[9]  F. Uckun,et al.  Pretransplantation burden of leukemic progenitor cells as a predictor of relapse after bone marrow transplantation for acute lymphoblastic leukemia. , 1993, The New England journal of medicine.

[10]  C. Poulter,et al.  Prenylated proteins. A convenient synthesis of farnesyl cysteinyl thioethers , 1991 .

[11]  E. Shaw,et al.  Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases. , 1981, The Journal of biological chemistry.