Negative Regulation of dE2F1 by Cyclin-Dependent Kinases Controls Cell Cycle Timing

[1]  N. Dyson,et al.  Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. , 2003, Genes & development.

[2]  W. Du,et al.  Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development , 2003, The EMBO journal.

[3]  P. O’Farrell,et al.  Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila , 2003, BMC Genetics.

[4]  B. Edgar,et al.  Rheb promotes cell growth as a component of the insulin/TOR signalling network , 2003, Nature Cell Biology.

[5]  E. Hafen,et al.  Rheb is an essential regulator of S6K in controlling cell growth in Drosophila , 2003, Nature Cell Biology.

[6]  R. Duronio,et al.  The Contribution of E2F-Regulated Transcription to Drosophila PCNA Gene Function , 2003, Current Biology.

[7]  N. Dyson,et al.  Functional antagonism between E2F family members. , 2001, Genes & development.

[8]  R. Spang,et al.  Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis , 2001, Molecular and Cellular Biology.

[9]  W. Du,et al.  DNA replication control through interaction of E2F–RB and the origin recognition complex , 2001, Nature Cell Biology.

[10]  M. Pagano,et al.  Regulation of the G1 to S transition by the ubiquitin pathway , 2001, FEBS letters.

[11]  E. Wieschaus,et al.  A Genetic Link between Morphogenesis and Cell Division during Formation of the Ventral Furrow in Drosophila , 2000, Cell.

[12]  Juan Mata,et al.  Tribbles Coordinates Mitosis and Morphogenesis in Drosophila by Regulating String/CDC25 Proteolysis , 2000, Cell.

[13]  P. O’Farrell,et al.  Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. , 2000, Genetics.

[14]  D. Prober,et al.  Ras1 Promotes Cellular Growth in the Drosophila Wing , 2000, Cell.

[15]  E. Wilder,et al.  Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB , 1999, Nature Cell Biology.

[16]  T. P. Neufeld,et al.  Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor , 1999, Current Biology.

[17]  D. Prober,et al.  Drosophila myc Regulates Cellular Growth during Development , 1999, Cell.

[18]  M. Scheffner,et al.  Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation , 1999, Nature Cell Biology.

[19]  D. Livingston,et al.  Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[20]  T. P. Neufeld,et al.  Coordination of Growth and Cell Division in the Drosophila Wing , 1998, Cell.

[21]  P. O’Farrell,et al.  Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. , 1998, Genes & development.

[22]  W. Krek,et al.  Proteolysis and the G1-S transition: the SCF connection. , 1998, Current opinion in genetics & development.

[23]  P. O’Farrell,et al.  Mutations of the Drosophila dDP,dE2F, and cyclin E Genes Reveal Distinct Roles for the E2F-DP Transcription Factor and Cyclin E during the G1-S Transition , 1998, Molecular and Cellular Biology.

[24]  P. Kylsten,et al.  Imaginal tissues of Drosophila melanogaster exhibit different modes of cell proliferation control. , 1997, Developmental Biology.

[25]  C. Lehner,et al.  Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. , 1997, Development.

[26]  I. Royzman,et al.  Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. , 1997, Genes & development.

[27]  B. Dynlacht,et al.  Specific regulation of E2F family members by cyclin-dependent kinases , 1997, Molecular and cellular biology.

[28]  E. Flemington,et al.  Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[29]  S. Zipursky,et al.  Induction of Drosophila eye development by decapentaplegic. , 1997, Development.

[30]  I. Hariharan,et al.  A Cyclin-Dependent Kinase Inhibitor, Dacapo, Is Necessary for Timely Exit from the Cell Cycle during Drosophila Embryogenesis , 1996, Cell.

[31]  Yuh Nung Jan,et al.  Dacapo, a Cyclin-Dependent Kinase Inhibitor, Stops Cell Proliferation during Drosophila Development , 1996, Cell.

[32]  A. Shvarts,et al.  Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. , 1996, Genes & development.

[33]  D. Livingston,et al.  The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. , 1996, Genes & development.

[34]  J. Bartek,et al.  The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. , 1996, Cancer research.

[35]  G. Schubiger,et al.  Ectopic expression of wingless in imaginal discs interferes with decapentaplegic expression and alters cell determination. , 1996, Development.

[36]  A. Garcı́a-Bellido,et al.  Cell cycling and patterned cell proliferation in the Drosophila wing during metamorphosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[37]  P. O’Farrell,et al.  E2F-induced S phase requires cyclin E. , 1996, Genes & development.

[38]  B. Edgar,et al.  Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. , 1996, Genes & development.

[39]  N. Dyson,et al.  Requirements for dE2F function in proliferating cells and in post‐mitotic differentiating cells. , 1996, The EMBO journal.

[40]  J. Nevins,et al.  Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. , 1996, Genes & development.

[41]  T. Jacks,et al.  Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1 , 1996, Cell.

[42]  M. Vidal,et al.  RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. , 1996, Genes & development.

[43]  A. Garcı́a-Bellido,et al.  Cell cycling and patterned cell proliferation in the wing primordium of Drosophila. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[44]  P. O’Farrell,et al.  Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. , 1995, Molecular biology of the cell.

[45]  P. O’Farrell,et al.  The transcription factor E2F is required for S phase during Drosophila embryogenesis. , 1995, Genes & development.

[46]  P. O’Farrell,et al.  Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F. , 1995, Genes & development.

[47]  James M. Roberts,et al.  Human cyclin E, a nuclear protein essential for the G1-to-S phase transition , 1995, Molecular and cellular biology.

[48]  E. Bier,et al.  Double-label in situ hybridization using biotin and digoxigenin-tagged RNA probes. , 1994, BioTechniques.

[49]  Wilhelm Krek,et al.  Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase , 1994, Cell.

[50]  J. Nevins,et al.  Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. , 1994, Genes & development.

[51]  C. Lehner,et al.  Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation , 1994, Cell.

[52]  M. Gossen,et al.  Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. , 1994, Molecular and cellular biology.

[53]  P. O’Farrell,et al.  Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. , 1994, Genes & development.

[54]  James M. Roberts,et al.  Cyclin-dependent regulation of G1 in mammalian fibroblasts. , 1993, Science.

[55]  P. O’Farrell,et al.  The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string , 1990, Cell.

[56]  J. Maller,et al.  Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle , 1989, Nature.

[57]  Andrew W. Murray,et al.  The role of cyclin synthesis and degradation in the control of maturation promoting factor activity , 1989, Nature.

[58]  Andrew W. Murray,et al.  Cyclin synthesis drives the early embryonic cell cycle , 1989, Nature.

[59]  P. O’Farrell,et al.  Genetic control of cell division patterns in the Drosophila embryo , 1989, Cell.

[60]  P. O’Farrell,et al.  Expression and function of Drosophila cyclin a during embryonic cell cycle progression , 1989, Cell.

[61]  G. Tokiwa,et al.  The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. , 1988, The EMBO journal.

[62]  Paul Russell,et al.  cdc25 + functions as an inducer in the mitotic control of fission yeast , 1986, Cell.

[63]  P. Thuriaux,et al.  Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. , 1980, Genetics.

[64]  H. Schneiderman,et al.  Histological analysis of the dynamics of growth of imaginal discs and histoblast nests during the larval development ofDrosophila melanogaster , 1977, Wilhelm Roux's archives of developmental biology.

[65]  D. Balasubramanian,et al.  Mutations , 2003, Human Genetics.

[66]  A. Garcı́a-Bellido,et al.  Parameters of the wing imaginal disc development of Drosophila melanogaster. , 1971, Developmental biology.