The role of tumour necrosis factor (TNF-α) in experimental autoimmune uveoretinitis (EAU)
暂无分享,去创建一个
[1] L. Old,et al. Tumor necrosis factor (TNF). , 1985, Science.
[2] J. Sedgwick,et al. Microglia induce CD4 T lymphocyte final effector function and death , 1996, The Journal of experimental medicine.
[3] J. Forrester,et al. Immunopathogenic mechanisms in intraocular inflammation. , 1999, Chemical immunology.
[4] B. Haynes,et al. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. , 1996, Immunity.
[5] N. Sicotte,et al. Onset of multiple sclerosis associated with anti-TNF therapy , 2001, Neurology.
[6] J. Forrester,et al. CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for the CD2-mediated alternative pathway of T cell activation. , 1996, Journal of immunology.
[7] A. Dick,et al. Systemic CD4+ T cell phenotype and activation status in intermediate uveitis , 2004, British Journal of Ophthalmology.
[8] P. Hart,et al. Mice deficient in tumor necrosis factor receptors p55 and p75, interleukin-4, or inducible nitric oxide synthase are susceptible to endotoxin-induced uveitis. , 1998, Investigative ophthalmology & visual science.
[9] A. D. de Vos,et al. Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis in the rat. , 1994, Investigative ophthalmology & visual science.
[10] A. Dick,et al. Generation of activated sialoadhesin-positive microglia during retinal degeneration. , 2003, Investigative ophthalmology & visual science.
[11] Y. Courtois,et al. Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor beta in bovine retinal pigmented epithelial cells: inverse correlation with cellular proliferation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[12] I. Gery,et al. Experimental autoimmune uveoretinitis , 1996 .
[13] J. Streilein. Ocular immune privilege: the eye takes a dim but practical view of immunity and inflammation , 2003, Journal of leukocyte biology.
[14] B. Scallon,et al. Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor‐immunoglobulin fusion proteins , 1994, European journal of immunology.
[15] F. Brennan,et al. CD45-induced Tumor Necrosis Factor α Production in Monocytes Is Phosphatidylinositol 3-Kinase-dependent and Nuclear Factor-κB-independent* , 1999, The Journal of Biological Chemistry.
[16] W. Wacker. Proctor Lecture. Experimental allergic uveitis. Investigations of retinal autoimmunity and the immunopathologic responses evoked. , 1991, Investigative ophthalmology & visual science.
[17] C. Ware,et al. Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells. , 1991, Journal of immunology.
[18] E. Collantes Estévez,et al. Aqueous Humor and Serum Tumor Necrosis Factor-α in Clinical Uveitis , 2001, Ophthalmic Research.
[19] M. Cook,et al. Distinct roles for lymphotoxin‐α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue , 1997 .
[20] J. Forrester,et al. Experimental autoimmune uveoretinitis: a model system for immunointervention: a review. , 1992, Current eye research.
[21] J. Forrester. Macrophages eyed in macular degeneration , 2003, Nature Medicine.
[22] C. Jacob,et al. Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis , 1988, Nature.
[23] D. Wesemann,et al. STAT-1α and IFN-γ as Modulators of TNF-α Signaling in Macrophages: Regulation and Functional Implications of the TNF Receptor 1:STAT-1α Complex1 , 2003, The Journal of Immunology.
[24] R. Kastelein,et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain , 2003, Nature.
[25] A. Dick,et al. CD200 maintains microglial potential to migrate in adult human retinal explant model , 2004, Current eye research.
[26] Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis. , 1998, Journal of immunology.
[27] Justine R. Smith,et al. Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease. , 2001, Arthritis and rheumatism.
[28] A. Dick,et al. Flow cytometric identification of a minority population of MHC class II positive cells in the normal rat retina distinct from CD45lowCD11b/c+CD4low parenchymal microglia. , 1995, The British journal of ophthalmology.
[29] F. Cunha,et al. TNF‐α mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis , 2003, European journal of immunology.
[30] George Kollias,et al. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor , 1995, Cell.
[31] H. Mcdevitt,et al. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. Caspi. Immunogenetic aspects of clinical and experimental uveitis. , 1992, Regional immunology.
[33] A. Dick,et al. Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis. , 2002, The American journal of pathology.
[34] J. Forrester,et al. Anti-TNFalpha therapy modulates the phenotype of peripheral blood CD4+ T cells in patients with posterior segment intraocular inflammation. , 2004, Investigative ophthalmology & visual science.
[35] S. Haskill,et al. Expression of interleukin-1α, interleukin-1β, and an interleukin-1 receptor antagonist in human retinal pigment epithelial cells , 1992 .
[36] H. Yazıcı,et al. TNF, soluble IL-2R and soluble CD-8 in Behçet's disease. , 1990, The Journal of rheumatology.
[37] G. Wu,et al. Role of retinal pigment epithelium in the development of experimental autoimmune uveitis. , 1994, Investigative ophthalmology & visual science.
[38] R. Clark,et al. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis , 1990, The Journal of experimental medicine.
[39] H. Ideta,et al. Immunogenetic study of sympathetic ophthalmia. , 1997, Tissue antigens.
[40] Peter Scheurich,et al. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF‐R1 activation by endogenous membrane‐anchored TNF , 1999, The EMBO journal.
[41] P. Wiedemann,et al. Modulation of matrix metalloproteinase and TIMP-1 expression by cytokines in human RPE cells. , 2002, Investigative ophthalmology & visual science.
[42] A. Dick,et al. Immune regulation of uveoretinal inflammation. , 1999, Developments in ophthalmology.
[43] J. Forrester,et al. IL-18 not required for IRBP peptide-induced EAU: studies in gene-deficient mice. , 2001, Investigative ophthalmology & visual science.
[44] J. Tschopp,et al. Caspase-independent cell death in T lymphocytes , 2003, Nature Immunology.
[45] Jeffrey A. Bluestone,et al. Opinion-regulatory lymphocytes: Natural versus adaptive regulatory T cells , 2003, Nature Reviews Immunology.
[46] D. Jayne,et al. Tumor necrosis factor α blockade with infliximab for refractory uveitis and scleritis , 2004 .
[47] W. Roberts,et al. Monocyte-induced cytokine expression in cultured human retinal pigment epithelial cells. , 1995, Experimental eye research.
[48] A. Cope,et al. Prolonged Exposure of T Cells to TNF Down-Regulates TCRζ and Expression of the TCR/CD3 Complex at the Cell Surface1 , 2001, The Journal of Immunology.
[49] A. D. de Vos,et al. Expression of multiple forms of IL‐1 receptor antagonist (IL‐1ra) by human retinal pigment epithelial cells: identification of a new IL‐1ra exon , 1999, European journal of immunology.
[50] C. Y. Wang,et al. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.
[51] J. Provis,et al. Human retinal microglia: Expression of immune markers and relationship to the Glia limitans , 1995, Glia.
[52] A. Cope,et al. Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis. , 1994, The Journal of clinical investigation.
[53] M. V. van Krugten,et al. Polymorphism within the tumor necrosis factor alpha (TNF) promoter region in patients with ankylosing spondylitis. , 1999, Human immunology.
[54] R. Cohen. Infliximab at 5 years--tweaking the recipe for success? , 2003, Gastroenterology.
[55] H. Krutzsch,et al. Thrombospondin-1 is a major activator of TGF-β in fibrotic renal disease in the rat in vivo , 2004 .
[56] I. McInnes,et al. Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis , 1997, Nature Medicine.
[57] J. Dayer,et al. The role of human T-lymphocyte-monocyte contact in inflammation and tissue destruction , 2002, Arthritis research.
[58] J. Forrester,et al. Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis. , 2003, Investigative ophthalmology & visual science.
[59] J. Forrester,et al. Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism. , 1997, Journal of immunology.
[60] J. Forrester,et al. Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis. , 2002, The American journal of pathology.
[61] W. Wacker,et al. Experimental allergic uveitis. I. Production in the guinea pig and rabbit by immunization with retina in adjuvant. , 1968, Journal of immunology.
[62] J. V. Falvo,et al. Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter , 2000, Molecular and Cellular Biology.
[63] J. Forrester,et al. Ultrastructural pathology of the 'barrier sites' in experimental autoimmune uveitis and experimental autoimmune pinealitis. , 1991, The British journal of ophthalmology.
[64] J. Forrester,et al. Expression of the chemokines MIP-1alpha, MCP-1, and RANTES in experimental autoimmune uveitis. , 2001, Investigative ophthalmology & visual science.
[65] I. Gery,et al. Inhibition of experimental autoimmune uveoretinitis by mycophenolate mofetil, an inhibitor of purine metabolism. , 1995, Experimental eye research.
[66] H. Er,et al. Serum levels of TNF-alpha, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease. , 2002, Mediators of inflammation.
[67] G. Lutty,et al. T cell traffic and the inflammatory response in experimental autoimmune uveoretinitis. , 1998, Investigative ophthalmology & visual science.
[68] J. Dayer,et al. Direct contact with stimulated T cells induces the expression of IL-1beta and IL-1 receptor antagonist in human monocytes. Involvement of serine/threonine phosphatases in differential regulation. , 1997, Cytokine.
[69] D. Männel,et al. Cytokine induction by immunomodulatory epitopes in S-antigen and tumor necrosis factor alpha. , 1992, Current eye research.
[70] W. Wacker. Retinal autoimmunity: two decades of research. , 1987, Japanese journal of ophthalmology.
[71] Holtkamp,et al. Analysis of the secretion pattern of monocyte chemotactic protein‐1 (MCP‐1) and transforming growth factor‐beta 2 (TGF‐β2) by human retinal pigment epithelial cells , 1999, Clinical and experimental immunology.
[72] G. Chader,et al. Genetic control of susceptibility to experimental autoimmune uveoretinitis in the mouse model: Concomitant regulation by MHC and non-MHC genes , 1991, Journal of Neuroimmunology.
[73] A. Cope,et al. Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints , 1992, European journal of immunology.
[74] D. Green,et al. CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. , 1996, Immunity.
[75] T. Maniatis,et al. Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[76] Y. de Kozak,et al. Immunological characterization of an immunomodulatory epitope in S-antigen/arrestin with a sequence motif common to tumor necrosis factor alpha. , 1992, Immunology letters.
[77] D. Kioussis,et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. , 1991, The EMBO journal.
[78] A. Barclay,et al. CD200 and membrane protein interactions in the control of myeloid cells. , 2002, Trends in immunology.
[79] J. Forrester,et al. Ultrastructural pathology of experimental autoimmune uveitis. Quantitative evidence of activation and possible high endothelial venule-like changes in retinal vascular endothelium. , 1992, Laboratory investigation; a journal of technical methods and pathology.
[80] I. Gery,et al. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. , 1986, Journal of immunology.
[81] Y. Courtois,et al. Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines. , 1994, Biochemical and biophysical research communications.
[82] A. Cope,et al. Soluble TNF receptor production by activated T lymphocytes: differential effects of acute and chronic exposure to TNF. , 1995, Immunology.
[83] M. Mochizuki,et al. Cytokine production by T cells infiltrating in the eye of uveitis patients. , 1998, Japanese journal of ophthalmology.
[84] J. Rosenbaum,et al. IL-1 and TNF receptor-deficient mice show decreased inflammation in an immune complex model of uveitis. , 1999, Investigative ophthalmology & visual science.
[85] S. Rennard,et al. Interferon-γ Inhibits Transforming Growth Factor-β Production in Human Airway Epithelial Cells by Targeting Smads , 2004 .
[86] N. Ruddle. Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development. , 1999, Immunologic research.
[87] G. Kollias,et al. Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling , 1997, The Journal of experimental medicine.
[88] H. Mcdevitt,et al. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. , 1996, Immunity.
[89] H. Inoko,et al. HLA-DRB1 typing of Vogt-Koyanagi-Harada's disease by PCR-RFLP and the strong association with DRB1*0405 and DRB1*0410. , 1994, The British journal of ophthalmology.
[90] A. Rees,et al. Macrophages from inflamed but not normal glomeruli are unresponsive to anti-inflammatory cytokines. , 2000, The American journal of pathology.
[91] L. Kasner,et al. The paradoxical effect of tumor necrosis factor alpha (TNF-alpha) in endotoxin-induced uveitis. , 1993, Investigative ophthalmology & visual science.
[92] N. Yoshimura,et al. Tumor necrosis factor-α gene is expressed in stimulated retinal pigment epithelial cells in culture , 1992 .
[93] S. Ohno,et al. The role of tumor necrosis factor-alpha in the induction of experimental autoimmune uveoretinitis in mice. , 1994, Investigative ophthalmology & visual science.
[94] G. Shaw,et al. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation , 1986, Cell.
[95] J. Woody,et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis , 1994, The Lancet.
[96] J. Forrester,et al. Cytokine regulation of RANTES production by human retinal pigment epithelial cells. , 1998, Cellular immunology.
[97] Y. de Kozak,et al. Humoral immune response against the S-antigen/TNF alpha common epitope in rat EAU suppressed by the monoclonal antibody S2D2. , 1992, Current eye research.
[98] P. Lipsky,et al. Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-alpha. , 1988, Journal of immunology.
[99] D. Riches,et al. Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states. , 1993, The American journal of pathology.
[100] A. Dick,et al. IFN-γ and LPS-Mediated IL-10–Dependent Suppression of Retinal Microglial Activation , 2000 .
[101] A. Rees,et al. Previous uptake of apoptotic neutrophils or ligation of integrin receptors downmodulates the ability of macrophages to ingest apoptotic neutrophils. , 1999, Blood.
[102] M. Matsuoka,et al. Polymorphism of the 5'-flanking region of the tumor necrosis factor (TNF)-alpha gene and susceptibility to human T-cell lymphotropic virus type I (HTLV-I) uveitis. , 1999, The Journal of infectious diseases.
[103] D. S. Mcleod,et al. Inhibition of TNF-α–induced Sickle RBC Retention in Retina by a VLA-4 Antagonist , 2001 .
[104] A. Turnley,et al. Interferon-γ but not TNFα promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells , 2004, Experimental Neurology.
[105] J. Forrester,et al. Involvement of CD44 in leukocyte trafficking at the blood‐retinal barrier , 2002, Journal of leukocyte biology.
[106] M. Lenardo,et al. Induction of apoptosis in mature T cells by tumour necrosis factor , 1995, Nature.
[107] J. Forrester,et al. TGF-beta and IL-1 beta act in synergy to enhance IL-6 and IL-8 mRNA levels and IL-6 production by human retinal pigment epithelial cells. , 1995, Immunology.
[108] A. Dick,et al. Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis. , 1998, Journal of autoimmunity.
[109] J. Abe,et al. Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation , 2003, The Journal of experimental medicine.
[110] G. Courtois,et al. Mature T cells depend on signaling through the IKK complex. , 2003, Immunity.
[111] J. Provis,et al. Microglia in human retina: a heterogeneous population with distinct ontogenies. , 1996, Perspectives on developmental neurobiology.
[112] Rosenbaum Jt,et al. Failure to inhibit endotoxin-induced uveitis with antibodies that neutralize tumor necrosis factor. , 1993 .
[113] M. Smet,et al. Regulation of Ocular Inflammation — What Experimental and Human Studies have Taught Us , 2001, Progress in Retinal and Eye Research.
[114] A. Elezoglou,et al. Serum Levels of Soluble TNF-α Receptor-II (P75), Circulating γδ T-Cells and Adamantiades-behçet’s Disease Activity , 2004 .
[115] R. Rezzonico,et al. Th2 Cell Membrane Factors in Association with IL-4 Enhance Matrix Metalloproteinase-1 (MMP-1) While Decreasing MMP-9 Production by Granulocyte-Macrophage Colony-Stimulating Factor-Differentiated Human Monocytes1 , 2000, The Journal of Immunology.
[116] S. Nedospasov,et al. The role of lymphotoxin in development and maintenance of secondary lymphoid tissues. , 2003, Cytokine & growth factor reviews.
[117] J. Forrester,et al. Cytokine regulation of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) production by human retinal pigment epithelial cells , 1999, Clinical and experimental immunology.
[118] G. Chaudhri,et al. Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system , 1997, European journal of immunology.
[119] J. Forrester,et al. Retinal antigen specific lymphocytes, TCR-gamma delta T cells and CD5+ B cells cultured from the vitreous in acute sympathetic ophthalmitis. , 1993, Autoimmunity.
[120] P. Kaye,et al. A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection. , 2002, The American journal of pathology.
[121] J. Sedgwick. T-lymphocyte activation and regulation in the central nervous system. , 1997, Biochemical Society transactions.
[122] S. Okuyama,et al. Modification of Glial–Neuronal Cell Interactions Prevents Photoreceptor Apoptosis during Light-Induced Retinal Degeneration , 2000, Neuron.
[123] D. Männel,et al. A common epitope on human tumor necrosis factor alpha and the autoantigen 'S-antigen/arrestin' induces TNF-alpha production. , 1992, Journal of autoimmunity.
[124] M. Naud,et al. Differential tumor necrosis factor expression by resident retinal cells from experimental uveitis-susceptible and -resistant rat strains , 1994, Journal of Neuroimmunology.
[125] J. Forrester,et al. Dendritic cells and "dendritic" macrophages in the uveal tract. , 1993, Advances in experimental medicine and biology.
[126] H. Kaplan,et al. Kinetics of cytokine production in experimental autoimmune anterior uveitis (EAAU). , 1998, Current eye research.
[127] A. D. de Vos,et al. Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat. , 1994, Investigative ophthalmology & visual science.
[128] J. Forrester,et al. Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis. , 2004, Archives of ophthalmology.
[129] W. Wacker,et al. Experimental Allergic Uveitis : Homologous Retina as Uveitogenic Antigen , 1965, Nature.
[130] J. Robertson,et al. Retinal pigment epithelial cells produce interleukin-1β and granulocyte-macrophage colony-stimulating factor in response to interleukin-1α , 1993 .
[131] C. López-Larrea,et al. TNF-238A promoter polymorphism contributes to susceptibility to ankylosing spondylitis in HLA-B27 negative patients. , 2001, The Journal of rheumatology.
[132] D. Baker,et al. Interphotoreceptor retinoid binding protein peptide-induced uveitis in B10.RIII mice: characterization of disease parameters and immunomodulation. , 2001, Experimental eye research.
[133] D. Gregerson,et al. CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-gamma or anti-CD40. , 2003, Investigative ophthalmology & visual science.
[134] H. Eng,et al. Cytokine gene expression in different strains of mice with endotoxin-induced uveitis (EIU) , 2000, Ocular immunology and inflammation.
[135] J. Forrester,et al. Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis. , 2002, Investigative ophthalmology & visual science.
[136] K. Ayed,et al. Production of TNF-alpha and IL-1 in active Behçet's disease. , 1990, The Journal of rheumatology.
[137] A. Rees,et al. Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines. , 1998, Journal of immunology.
[138] R. Nussenblatt,et al. Glial retinal Müller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes. Antigen presentation manifested after removal of suppressive activity. , 1988, Journal of immunology.
[139] J. Cyster,et al. Follicular stromal cells and lymphocyte homing to follicles , 2000, Immunological reviews.
[140] U. Ozbek,et al. Tumour necrosis factor-alpha gene promoter region -308 and -376 G-->A polymorphisms in Behçet's disease. , 2003, Clinical and experimental rheumatology.
[141] M. Mochizuki,et al. Effects of FK506, 15-deoxyspergualin, and cyclosporine on experimental autoimmune uveoretinitis in the rat. , 1990, Autoimmunity.
[142] V. Singh,et al. Experimental autoimmune uveitis as animal model for human posterior uveitis. , 1998, The Indian journal of medical research.
[143] J. Forrester,et al. Control of myeloid activity during retinal inflammation , 2003, Journal of leukocyte biology.
[144] K Eichmann,et al. Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. , 1999, Journal of immunology.
[145] N. Rao,et al. Hematopoietically derived retinal perivascular microglia initiate uveoretinitis in experimental autoimmune uveitis , 2000, Graefe's Archive for Clinical and Experimental Ophthalmology.
[146] V. K. Singh,et al. Cytokines in posterior uveitis , 2001, Immunologic research.
[147] J. Cyster,et al. Tumor necrosis factor: a master-regulator of leukocyte movement. , 2000, Immunology today.
[148] D. Wofsy,et al. Effects of recombinant murine tumor necrosis factor-alpha on immune function. , 1990, Journal of immunology.
[149] J. Forrester,et al. Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice. , 1999, Investigative ophthalmology & visual science.
[150] J. Forrester,et al. Campath-1H therapy in refractory ocular inflammatory disease , 2000, The British journal of ophthalmology.
[151] J. Mizuguchi,et al. Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats. , 1998, Ocular immunology and inflammation.
[152] J. Forrester,et al. Leukocyte trafficking in experimental autoimmune uveitis: breakdown of blood-retinal barrier and upregulation of cellular adhesion molecules. , 2003, Investigative ophthalmology & visual science.
[153] R. Nussenblatt,et al. FK 506 treatment of experimental autoimmune uveoretinitis in primates. , 1991, Transplantation proceedings.
[154] S. Hedrick,et al. TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection. , 1998, Journal of immunology.
[155] B. Thillaye‐Goldenberg,et al. Tumor necrosis factor and nitric oxide production by resident retinal glial cells from rats presenting hereditary retinal degeneration. , 1997, Ocular immunology and inflammation.
[156] J. Ochoa,et al. l-Arginine Consumption by Macrophages Modulates the Expression of CD3ζ Chain in T Lymphocytes1 , 2003, The Journal of Immunology.
[157] T. Griffith,et al. The role of FasL-induced apoptosis in immune privilege. , 1997, Immunology today.
[158] J. Forrester,et al. Immunogenetics and clinical phenotype of sympathetic ophthalmia in British and Irish patients , 2001, The British journal of ophthalmology.
[159] R. Siegel,et al. Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. , 1999, Annual review of immunology.
[160] P. Sharp,et al. Effect of anti‐macrophage inflammatory protein‐1α on leukocyte trafficking and disease progression in experimental autoimmune uveoretinitis , 2003, European journal of immunology.
[161] E. Perez-Luque,et al. Strong association of HLA class II sequences in Mexicans with Vogt-Koyanagi-Harada's disease. , 1999, Human immunology.
[162] R. M. Sharrard,et al. Cytokine modulation of adhesion molecule expression on human retinal pigment epithelial cells. , 1995, Investigative ophthalmology & visual science.
[163] A. D. de Vos,et al. Tumour necrosis factor-induced uveitis in the Lewis rat is associated with intraocular interleukin 6 production. , 1995, Experimental eye research.
[164] S. Peltz,et al. The cap-to-tail guide to mRNA turnover , 2001, Nature Reviews Molecular Cell Biology.
[165] B. Blom,et al. Down-regulation of the macrophage lineage through interaction with OX2 (CD200). , 2000, Science.
[166] H. Dua,et al. Infliximab in the treatment of refractory posterior uveitis. , 2003, Ophthalmology.
[167] P. Sharp,et al. Recruitment of IFN-γ-Producing (Th1-Like) Cells into the Inflamed Retina In Vivo Is Preferentially Regulated by P-Selectin Glycoprotein Ligand 1:P/E-Selectin Interactions1 , 2004, The Journal of Immunology.
[168] H. Lassmann,et al. Bone Marrow-derived Elements in the Central Nervous System: An Immunohistochemical and Ultrastructural Survey of Rat Chimeras , 1992, Journal of neuropathology and experimental neurology.
[169] J. Forrester,et al. Ultrastructural pathology of experimental autoimmune uveitis: A review , 1993 .
[170] Ian F. Dunn,et al. A Lipopolysaccharide-Specific Enhancer Complex Involving Ets, Elk-1, Sp1, and CREB Binding Protein and p300 Is Recruited to the Tumor Necrosis Factor Alpha Promoter In Vivo , 2000, Molecular and Cellular Biology.
[171] R. Nussenblatt,et al. Modulation of experimental autoimmune uveitis with cyclosporin A. , 1982, Archives of ophthalmology.
[172] J. Rosenbaum,et al. Tumor necrosis factor-alpha is not essential in endotoxin induced eye inflammation: studies in cytokine receptor deficient mice. , 1998, The Journal of rheumatology.
[173] B. Kirchhof,et al. Contribution of TNF-alpha to leukocyte adhesion, vascular leakage, and apoptotic cell death in endotoxin-induced uveitis in vivo. , 2003, Investigative ophthalmology & visual science.
[174] M. Feldmann,et al. Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor‐α, but not interleukin‐10: Possible relevance to pathophysiology of rheumatoid arthritis , 1997, European journal of immunology.
[175] J. Forrester,et al. Rat retinal pigment epithelial cells express an inducible form of nitric oxide synthase and produce nitric oxide in response to inflammatory cytokines and activated T cells. , 1994, Immunology.
[176] S. Ito,et al. Pathogenic role of retinal microglia in experimental uveoretinitis. , 2003, Investigative ophthalmology & visual science.
[177] K. Wada,et al. Microglia–Müller Glia Cell Interactions Control Neurotrophic Factor Production during Light-Induced Retinal Degeneration , 2002, The Journal of Neuroscience.
[178] J. Cyster,et al. Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation. , 2001, Immunity.
[179] J. Forrester,et al. Control of chemokine production at the blood–retina barrier , 2000, Immunology.
[180] H. Link,et al. Is there a balance between microglia and astrocytes in regulating Th1/Th2-cell responses and neuropathologies? , 1999, Immunology today.
[181] George Kollias,et al. Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level , 2001, The Journal of experimental medicine.
[182] P. Wiedemann,et al. Changes in the mRNA expression of cytokines and chemokines by stimulated RPE cells in vitro. , 2000, Current eye research.
[183] C. Chan,et al. Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming. , 1996, Investigative ophthalmology & visual science.
[184] B. Beutler,et al. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[185] D. S. Webb,et al. LFA-3, CD44, and CD45: physiologic triggers of human monocyte TNF and IL-1 release. , 1990, Science.
[186] Kristi Kincaid,et al. M-1/M-2 Macrophages and the Th1/Th2 Paradigm1 , 2000, The Journal of Immunology.
[187] G. Kollias,et al. Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response , 1996, The Journal of experimental medicine.
[188] J. Mizuguchi,et al. Effect of type I interferon on experimental autoimmune uveoretinitis in rats. , 1998, Ocular immunology and inflammation.
[189] T. Griffith,et al. Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis , 1998, Journal of Experimental Medicine.
[190] A. Dick. Experimental approaches to specific immunotherapies in autoimmune disease: future treatment of endogenous posterior uveitis? , 1995, The British journal of ophthalmology.
[191] M. Martinetti,et al. Genetic heterogeneity in uveitis. , 1986, Disease markers.
[192] A. Dick,et al. Lipopolysaccharide/interferon-γ and not transforming growth factor β inhibits retinal microglial migration from retinal explant , 2003, The British journal of ophthalmology.
[193] C. Chan,et al. Evaluation of in vivo cytokine expression in EAU-susceptible and resistant rats: a role for IL-10 in resistance? , 2000, Experimental eye research.
[194] J. Woody,et al. Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis , 1994, The Lancet.
[195] T. Ahmad,et al. Mapping the HLA association in Behçet's disease: a role for tumor necrosis factor polymorphisms? , 2003, Arthritis and rheumatism.
[196] J. Forrester,et al. Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina , 1996, European journal of immunology.
[197] J. Dean,et al. Post‐transcriptional regulation of gene expression by mitogen‐activated protein kinase p38 , 2003, FEBS letters.
[198] J. Forrester,et al. Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats. , 1998, Current eye research.
[199] G. Kollias,et al. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. , 1999, Immunity.
[200] P. Wiedemann,et al. The influence of pro-inflammatory cytokines on human retinal pigment epithelium cell receptors , 2001, Graefe's Archive for Clinical and Experimental Ophthalmology.
[201] A Kijlstra,et al. Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation. , 1999, The American journal of pathology.
[202] A. Dick,et al. Nestin positive cells in adult human retina and in epiretinal membranes , 2003, The British journal of ophthalmology.
[203] F. Barkhof,et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2 , 1996, Neurology.
[204] C Danieli,et al. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products , 1995, The Journal of experimental medicine.
[205] S. Gordon. Alternative activation of macrophages , 2003, Nature Reviews Immunology.
[206] A. Dick,et al. Immunomodulation of autoimmune responses with monoclonal antibodies and immunoadhesins: treatment of ocular inflammatory disease in the next millennium , 1999, The British journal of ophthalmology.
[207] A. Dick,et al. Effects of mycophenolate mofetil on nasal mucosal tolerance induction. , 1998, Investigative ophthalmology & visual science.
[208] K. Barton,et al. Effects of CD8 depletion on retinal soluble antigen induced experimental autoimmune uveoretinitis. , 1993, Immunology.
[209] P. Theodossiadis,et al. Effect of infliximab on sight-threatening panuveitis in Behcet's disease , 2001, The Lancet.
[210] A. Ting,et al. A20 Inhibits Tumor Necrosis Factor (TNF) Alpha-Induced Apoptosis by Disrupting Recruitment of TRADD and RIP to the TNF Receptor 1 Complex in Jurkat T Cells , 2002, Molecular and Cellular Biology.
[211] Chi-Chao Chan,et al. Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune uveoretinitis , 1993, Journal of Neuroimmunology.
[212] A. Dick,et al. Induction or suppression of a B cell‐specific response to self antigen in vivo is dependent upon dendritic cell activation via the TNF‐α receptor at the time of antigen uptake , 2000, European journal of immunology.
[213] J. Pollard,et al. Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting , 1997, The Journal of experimental medicine.
[214] A. Kijlstra,et al. Retinal Pigment Epithelium-immune System Interactions: Cytokine Production and Cytokine-induced Changes , 2001, Progress in Retinal and Eye Research.
[215] Eiji Sakurai,et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice , 2003, Nature Medicine.
[216] S. Kunkel,et al. Anti-tumor necrosis factor antibodies suppress cell-mediated immunity in vivo. , 1992, Journal of immunology.
[217] L. Old,et al. Characterization of tumor necrosis factor-deficient mice. , 1997, Proceedings of the National Academy of Sciences of the United States of America.