In vitro cytotoxicity of low-dose-rate radioimmunotherapy by the alpha-emitting radioimmunoconjugate Thorium-227-DOTA-rituximab.

[1]  R. Larsen,et al.  Relative biologic effects of low-dose-rate alpha-emitting 227Th-rituximab and beta-emitting 90Y-tiuexetan-ibritumomab versus external beam X-radiation. , 2008, International journal of radiation oncology, biology, physics.

[2]  Ø. Bruland,et al.  Targeted cancer therapy with a novel low-dose rate α-emitting radioimmunoconjugate , 2007 .

[3]  T. Stokke,et al.  Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th. , 2007, Cancer biotherapy & radiopharmaceuticals.

[4]  R. Larsen,et al.  Preparation of TH227-labeled radioimmunoconjugates, assessment of serum stability and antigen binding ability. , 2007, Cancer biotherapy & radiopharmaceuticals.

[5]  D. Olsen,et al.  Initial evaluation of 227Th-p-benzyl-DOTA-rituximab for low-dose rate α-particle radioimmunotherapy , 2006 .

[6]  T. Stokke,et al.  The Response of Malignant B Lymphocytes to Ionizing Radiation: Cell Cycle Arrest, Apoptosis and Protection against the Cytotoxic Effects of the Mitotic Inhibitor Nocodazole , 2004, Radiation research.

[7]  H. Lundqvist,et al.  A limiting factor for the progress of radionuclide-based cancer diagnostics and therapy Availability of suitable radionuclides , 2004, Acta oncologica.

[8]  T. Stokke,et al.  Radioimmunotherapy with Alpha-Particle Emitters: Microdosimetry of Cells with a Heterogeneous Antigen Expression and with Various Diameters of Cells and Nuclei , 2001, Radiation research.

[9]  Y. Erdi,et al.  Pharmacokinetics and dosimetry of an alpha-particle emitter labeled antibody: 213Bi-HuM195 (anti-CD33) in patients with leukemia. , 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[10]  J F Ziegler,et al.  Comments on ICRU report no. 49: stopping powers and ranges for protons and alpha particles. , 1999, Radiation research.

[11]  J Moan,et al.  Cooperative effects of photodynamic treatment of cells in microcolonies. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[12]  C Haanen,et al.  A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. , 1995, Journal of immunological methods.

[13]  Ø. Bruland,et al.  Targeted cancer therapy with a novel low-dose rate alpha-emitting radioimmunoconjugate. , 2007, Blood.

[14]  G. Henriksen,et al.  Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents. , 2004, Anticancer research.