Isolated Parotid Acinar Cells from DL-Isoproterenol-treated Rats. A Cellular Model for Cystic Fibrosis

The morphology and composition of isolated acinar cells from the enlarged parotid glands of rats treated chronically with DL-isoproterenol were investigated and compared with isolated acinar cells from parotids of control untreated rats. Changes similar to those observed in parotid acinar cells from patients with cystic fibrosis were demonstrated.

[1]  W. Farnham,et al.  Calcium and cGMP in Isolated Rat Parotid Acinar Cells , 1980, Journal of dental research.

[2]  J. Mangos.  Characterization of Autonomic Receptors in Isolated Human Parotid Acinar Cells , 1980, Journal of dental research.

[3]  P. Davis,et al.  A Review. Cystic Fibrosis at Forty—Quo Vadis? , 1980, Pediatric Research.

[4]  J. Mangos.  Morphological and Functional Characterization of Isolated Human Parotid Acinar Cells , 1979, Journal of dentistry research.

[5]  J. Mangos.  Role of cGMP in Isolated Rat Parotid Acinar Cells , 1978, Journal of dental research.

[6]  T. Barber,et al.  Dispersed rat parotid acinar cells. I. Morphological and functional characterization. , 1975, The American journal of physiology.

[7]  T. Barber,et al.  Dispersed rat parotid acinar cells. II. Characterization of adrenergic receptors. , 1975, The American journal of physiology.

[8]  T. Barber,et al.  Dispersed rat parotid acinar cells. III. Characterization of cholinergic receptors. , 1975, The American journal of physiology.

[9]  D. Quissell,et al.  Abnormal secretory response to parasympathomimetic and sympathomimetic stimulations from the submaxillary gland of rats treated with reserpine. , 1975, The Journal of pharmacology and experimental therapeutics.

[10]  I. Mandel,et al.  Effect of Adrenergic Agents on Salivary Composition , 1975, Journal of dental research.

[11]  D. M. Carlson,et al.  Isolation of a "proline-rich" protein from rat parotid glands following isoproterenol treatment. , 1974, Biochemical and biophysical research communications.

[12]  J. Mangos,et al.  Autonomic regulation of secretion and transductal fluxes of ions in the rat parotid. , 1973, The American journal of physiology.

[13]  R. Baserga,et al.  Association of hypertrophy and DNA synthesis in mouse salivary glands after chronic administration of isoproterenol. , 1971, The American journal of pathology.

[14]  J. Gustafson,et al.  Cystic Fibrosis , 2009, Journal of the Iowa Medical Society.