Attention disorders in schizophrenia

Abstract  In order to clarify the feature of attention disorders in schizophrenia, two tasks (X and AX) of the Continuous Performance Test (CPT) were given to 36 schizophrenic patients and 25 healthy controls. The schizophrenic patients performed considerably less well than normal controls. Performances were expressed in indices such as omission and commission errors, reaction time and discriminability. Among errors, omission in both the X and AX tasks was found to be an index that varied in reaction time, indicating difficulty in sustaining attention. Omission was found to act as a state‐dependent index of schizophrenia in relation to inattentiveness in clinical settings and emotional disturbance in interpersonal situations. Commission, in contrast, differed between the two tasks, acting as an index of disinhibition of reaction in the X task, and of disturbance of the capacity and allocation of attention in the AX task. Commission was also thought to be an index related to thought disorder during episodes of acute schizophrenia, that is, it reflects an essential pathology in schizophrenia.

[1]  J. Grier,et al.  Nonparametric indexes for sensitivity and bias: computing formulas. , 1971, Psychological bulletin.

[2]  H E ROSVOLD,et al.  A continuous performance test of brain damage. , 1956, Journal of consulting psychology.

[3]  C. Kornetsky,et al.  The use of a simple test of attention as a measure of drug effects in schizophrenic patients , 2004, Psychopharmacologia.

[4]  L. Coyne,et al.  Phenothiazine effects on psychological and psychophysiological dysfunction in chronic schizophrenics. , 1977, Archives of general psychiatry.

[5]  H E ROSVOLD,et al.  A comparison of the psychological test performance of atients with focal and nonfocal epilepsy. , 1960, Experimental neurology.

[6]  W. Brouwer,et al.  Clinical Neuropsychology of Attention , 1994 .

[7]  K. Nuechterlein Signal detection in vigilance tasks and behavioral attributes among offspring of schizophrenic mothers and among hyperactive children. , 1983, Journal of abnormal psychology.

[8]  S. Cappa,et al.  Attentional dysfunction of chronic schizophrenia: No association with long‐term institutionalization , 2002, Psychiatry and clinical neurosciences.

[9]  C. Kornetsky,et al.  A research note on some of the critical factors on the dissimilar effects of chlorpromazine and secobarbital on the digit symbol substitution and continuous performance tests , 1964, Psychopharmacologia.

[10]  H. Grunebaum,et al.  Attention in young children of psychotic mothers. , 1974, The American journal of psychiatry.

[11]  D. M. Green,et al.  Signal detection theory and psychophysics , 1966 .

[12]  J. Grier,et al.  NONPARAMETRIC INDEXES FOR SENSITIVITY AND BIAS , 2005 .

[13]  B. Cornblatt,et al.  Global attentional deviance as a marker of risk for schizophrenia: specificity and predictive validity. , 1985, Journal of abnormal psychology.

[14]  K. Sax,et al.  Sustained attention and positive formal thought disorder in schizophrenia , 1994, Schizophrenia Research.

[15]  Information-processing anomalies in the early course of schizophrenia and bipolar disorder. , 1991, Schizophrenia research.

[16]  E. Niedermeyer,et al.  Clinical neuropsychology of attention , 1994 .

[17]  Attentional capacity dysfunction and arousal in schizophrenia. , 1983, Psychological bulletin.

[18]  R. Buchanan,et al.  Relations between attentional deficits and clinical symptoms in schizophrenic outpatients , 1993, Psychiatry Research.

[19]  M. Dawson,et al.  9. Information-processing anomalies in the early course of schizophrenia and bipolar disorder , 1991, Schizophrenia Research.

[20]  D. Alexander Attention Dysfunction in Senile Dementia , 1973, Psychological reports.

[21]  L. Buck Reaction time as a measure of perceptual vigilance. , 1966, Psychological bulletin.

[22]  N C Andreasen,et al.  Thought, language, and communication disorders. II. Diagnostic significance. , 1979, Archives of general psychiatry.

[23]  R. Asarnow,et al.  Residual performance deficit in clinically remitted schizophrenics: a marker of schizophrenia? , 1978, Journal of abnormal psychology.