Clinical Laboratory Tests: Which, Why, and What Do The Results Mean?

According to Dr. Michael Laposata, the medical specialty that nearly every practicing physician relies on every day, for which training in many medical schools is limited to no more than a scattered few lectures throughout the entire curriculum, is “laboratory medicine.” The importance of understanding the principles for selecting and ordering the most rational laboratory test(s) on a specific patient is heightened in the current age of managed care, medical necessity, and outcome-oriented medicine. The days of a “shotgun approach” to ordering laboratory tests has, of necessity, been replaced by a “rifle” (or targeted) approach based on an understanding of the test’s diagnostic performance and the major “legitimate” reasons for ordering a laboratory test. Such an understanding is critical to good laboratory practice and patient outcomes.

[1]  R. Forsman,et al.  Why is the laboratory an afterthought for managed care organizations? , 1996, Clinical chemistry.

[2]  Marianne Philippe,et al.  Application of the Six Sigma concept in clinical laboratories: a review , 2007, Clinical chemistry and laboratory medicine.

[3]  T. Gray,et al.  Learning needs in clinical biochemistry for doctors in foundation years , 2008, Annals of clinical biochemistry.

[4]  N. Obuchowski,et al.  ROC curves in clinical chemistry: uses, misuses, and possible solutions. , 2004, Clinical chemistry.

[5]  Robert W Veltri,et al.  Comparison of logistic regression and neural net modeling for prediction of prostate cancer pathologic stage. , 2002, Clinical chemistry.

[6]  C. Lamb Statistical briefing: estimating the probability of disease. , 2007, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

[7]  C. R. Schweiger,et al.  Evaluation of laboratory data by conventional statistics and by three types of neural networks. , 1993, Clinical chemistry.

[8]  Mario Plebani,et al.  Errors in a stat laboratory: types and frequencies 10 years later. , 2007, Clinical chemistry.