Localization of an Insulinoma by Endoscopic Ultrasound: A Case Report and Review of Diagnostic Modalities

Insulinomas are a type of pancreatic neuroendocrine tumor (pNET) that arises from pancreatic endocrine tissue. They are rare, with an estimated incidence of 4 cases per 1 million person-years. While typically larger pNETs are detectable using conventional imaging studies such as transabdominal ultrasound, CT, or MRI, insulinomas are frequently missed by conventional imaging due to their relatively small size. We present the case of a 66-year-old African American male with an insulinoma undetected by contrast-enhanced MRI, that was ultimately localized and diagnosed via endoscopic ultrasound (EUS) with fine needle aspiration (FNA).

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