Biomimicry in Bio-Manufacturing: Developments in Melt Electrospinning Writing Technology Towards Hybrid Biomanufacturing

[1]  P. Pokorný,et al.  Physical principles of electrospinning (Electrospinning as a nano-scale technology of the twenty-first century) , 2009 .

[2]  D. Hutmacher,et al.  Melt electrowriting of electroactive poly(vinylidene difluoride) fibers , 2018, Polymer International.

[3]  M. Kotaki,et al.  Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. , 2004, Biomaterials.

[4]  Jingyan Dong,et al.  Direct fabrication of high-resolution three-dimensional polymeric scaffolds using electrohydrodynamic hot jet plotting , 2013 .

[5]  Yan Peng,et al.  Electrospun 3D Fibrous Scaffolds for Chronic Wound Repair , 2016, Materials.

[6]  Paul D. Dalton,et al.  Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-ε-caprolactone and a collagen/poly-ε-caprolactone blend , 2007 .

[7]  Y. Truong,et al.  Melt-electrospinning of polypropylene with conductive additives , 2012, Journal of Materials Science.

[8]  Scott J Hollister,et al.  Additive manufacturing of polymer melts for implantable medical devices and scaffolds , 2017, Biofabrication.

[9]  Jiankang He,et al.  Development of melt electrohydrodynamic 3D printing for complex microscale poly (ε-caprolactone) scaffolds , 2016, Biofabrication.

[10]  Alessandro Reali,et al.  An Integrated Design, Material, and Fabrication Platform for Engineering Biomechanically and Biologically Functional Soft Tissues. , 2017, ACS applied materials & interfaces.

[11]  Dietmar W. Hutmacher,et al.  Melt electrospinning today: An opportune time for an emerging polymer process , 2016 .

[12]  M. Raghunath,et al.  Permanent Hydrophilization and Generic Bioactivation of Melt Electrowritten Scaffolds , 2019, Advanced healthcare materials.

[13]  P. Dalton,et al.  3D Electrophysiological Measurements on Cells Embedded within Fiber‐Reinforced Matrigel , 2019, Advanced healthcare materials.

[14]  Pouyan Ahangar,et al.  Current Biomedical Applications of 3D Printing and Additive Manufacturing , 2019, Applied Sciences.

[15]  P. Dalton,et al.  Additive manufacturing of scaffolds with sub-micron filaments via melt electrospinning writing , 2015, Biofabrication.

[16]  J. Malda,et al.  Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs , 2018, Advanced healthcare materials.

[17]  Yun-Ze Long,et al.  Melt electrospinning of poly(lactic acid) and polycaprolactone microfibers by using a hand-operated Wimshurst generator. , 2015, Nanoscale.

[18]  Liwei Lin,et al.  Near-field electrospinning. , 2006, Nano letters.

[19]  Tao Xu,et al.  Functionalization of PCL-3D Electrospun Nanofibrous Scaffolds for Improved BMP2-Induced Bone Formation. , 2017, Applied materials today.

[20]  C. Schauer,et al.  Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering. , 2012, Biomaterials.

[21]  Dietmar W. Hutmacher,et al.  Rational design and fabrication of multiphasic soft network composites for tissue engineering articular cartilage: A numerical model-based approach , 2018 .

[22]  Dong-Yol Yang,et al.  Development of dual scale scaffolds via direct polymer melt deposition and electrospinning for applications in tissue regeneration. , 2008, Acta biomaterialia.

[23]  Geunhyung Kim,et al.  Direct electrospinning writing for producing 3D hybrid constructs consisting of microfibers and macro-struts for tissue engineering , 2016 .

[24]  Micah J. Green,et al.  Modeling of downstream heating in melt electrospinning of polymers , 2017 .

[25]  Dietmar W. Hutmacher,et al.  Effect of gelatin source and photoinitiator type on chondrocyte redifferentiation in gelatin methacryloyl-based tissue-engineered cartilage constructs. , 2019, Journal of materials chemistry. B.

[26]  R. Anandjiwala,et al.  An optimized melt spinning process to increase the productivity of nanofiber materials , 2016 .

[27]  D. Hutmacher,et al.  Melt electrospinning onto cylinders: effects of rotational velocity and collector diameter on morphology of tubular structures , 2015 .

[28]  Ho-Young Kim,et al.  Toward nanoscale three-dimensional printing: nanowalls built of electrospun nanofibers. , 2014, Langmuir : the ACS journal of surfaces and colloids.

[29]  P. Bártolo,et al.  Additive manufacturing of tissues and organs , 2012 .

[30]  P. Dalton,et al.  Dimension-Based Design of Melt Electrowritten Scaffolds. , 2018, Small.

[31]  Frank Ko,et al.  Melt-electrospinning. part I: processing parameters and geometric properties , 2004 .

[32]  Dietmar W Hutmacher,et al.  Melt electrospinning of poly(ε-caprolactone) scaffolds: phenomenological observations associated with collection and direct writing. , 2014, Materials science & engineering. C, Materials for biological applications.

[33]  F. Klocke,et al.  Consolidation phenomena in laser and powder-bed based layered manufacturing , 2007 .

[34]  J. Clements,et al.  A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns. , 2019, Biomaterials.

[35]  Y. Long,et al.  Morphology control of PLA microfibers and spheres via melt electrospinning , 2018 .

[36]  Younan Xia,et al.  Electrospinning of Nanofibers: Reinventing the Wheel? , 2004 .

[37]  Dongxu Ke,et al.  Additive manufacturing of biomaterials. , 2018, Progress in materials science.

[38]  He Lian,et al.  Melt electrospinning vs. solution electrospinning: A comparative study of drug-loaded poly (ε-caprolactone) fibres. , 2017, Materials science & engineering. C, Materials for biological applications.

[39]  Tim R. Dargaville,et al.  Dermal fibroblast infiltration of poly(ε-caprolactone) scaffolds fabricated by melt electrospinning in a direct writing mode , 2013, Biofabrication.

[40]  D. Kalyon,et al.  Melt Electrospinning Writing Process Guided by a “Printability Number” , 2017 .

[41]  Xiaofeng Cui,et al.  Application of inkjet printing to tissue engineering , 2006, Biotechnology journal.

[42]  Onur Bas,et al.  Melt Electrospinning Writing of Highly Ordered Large Volume Scaffold Architectures , 2018, Advanced materials.

[43]  Quan Feng,et al.  Polymer blend nanofibers containing polycaprolactone as biocompatible and biodegradable binding agent to fabricate electrospun three-dimensional scaffolds/structures , 2018, Polymer.

[44]  D. Mooney,et al.  Hydrogels for tissue engineering: scaffold design variables and applications. , 2003, Biomaterials.

[45]  Hyeongjin Lee,et al.  A new hybrid scaffold constructed of solid freeform-fabricated PCL struts and collagen struts for bone tissue regeneration: fabrication, mechanical properties, and cellular activity , 2012 .

[46]  Zheng-ming Huang,et al.  Melt-electrospinning of PMMA , 2010 .

[47]  Patrick C. Lee,et al.  Fabrication of poly (ϵ-caprolactone) microfiber scaffolds with varying topography and mechanical properties for stem cell-based tissue engineering applications , 2014, Journal of biomaterials science. Polymer edition.

[48]  Hanna J. Sanyour,et al.  Tailoring weight ratio of PCL/PLA in electrospun three-dimensional nanofibrous scaffolds and the effect on osteogenic differentiation of stem cells. , 2018, Colloids and surfaces. B, Biointerfaces.

[49]  T. B. Green,et al.  The thermal effects on electrospinning of polylactic acid melts , 2006 .

[50]  Dietmar W. Hutmacher,et al.  Additive Biomanufacturing: An Advanced Approach for Periodontal Tissue Regeneration , 2016, Annals of Biomedical Engineering.

[51]  M. M. Bubakir,et al.  Mass production of ultra-fine fibre by melt electrospinning method using umbellate spinneret , 2014 .

[52]  Junghyuk Ko,et al.  Electrospun biomaterial scaffolds with varied topographies for neuronal differentiation of human-induced pluripotent stem cells. , 2015, Journal of biomedical materials research. Part A.

[53]  Yong Zhao,et al.  Electrospun Polycaprolactone 3D Nanofibrous Scaffold with Interconnected and Hierarchically Structured Pores for Bone Tissue Engineering , 2015, Advanced healthcare materials.

[54]  GeunHyung Kim,et al.  A new hybrid scaffold using rapid prototyping and electrohydrodynamic direct writing for bone tissue regeneration , 2011 .

[55]  Michael J Yaszemski,et al.  Poly(propylene fumarate) bone tissue engineering scaffold fabrication using stereolithography: effects of resin formulations and laser parameters. , 2007, Biomacromolecules.

[56]  E. Şimşek,et al.  Tunable, superhydrophobically stable polymeric surfaces by electrospinning. , 2004, Angewandte Chemie.

[57]  P. Dalton,et al.  Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration – a pilot study in vitro , 2019, BMC Oral Health.

[58]  Micah J. Green,et al.  Wire Melt Electrospinning of Thin Polymeric Fibers via Strong Electrostatic Field Gradients , 2018, Macromolecular Materials and Engineering.

[59]  Kristi L. Kiick,et al.  Designing degradable hydrogels for orthogonal control of cell microenvironments , 2013, Chemical Society reviews.

[60]  Congju Li,et al.  Preparation and characterization of poly(ɛ-caprolactone) nonwoven mats via melt electrospinning , 2012 .

[61]  Weizhi Wang,et al.  Crystallization behavior of poly(ε-caprolactone)/layered double hydroxide nanocomposites , 2010 .

[62]  P. Doevendans,et al.  Melt Electrospinning Writing of Poly‐Hydroxymethylglycolide‐co‐ε‐Caprolactone‐Based Scaffolds for Cardiac Tissue Engineering , 2017, Advanced healthcare materials.

[63]  M. Soleimani,et al.  The Effects of Plasma Treated Electrospun Nanofibrous Poly (ε-caprolactone) Scaffolds with Different Orientations on Mouse Embryonic Stem Cell Proliferation , 2014, Cell journal.

[64]  A. Hollander,et al.  Stem Cells and Cartilage Development: Complexities of a Simple Tissue , 2010, Stem cells.

[65]  Younan Xia,et al.  Collecting electrospun nanofibers with patterned electrodes. , 2005, Nano letters.

[66]  H. Yamane,et al.  Melt electrospinning: Electrodynamics and spinnability , 2017 .

[67]  J. Lannutti,et al.  Electrospinning for tissue engineering scaffolds , 2007 .

[68]  M. Modesti,et al.  Synthesis and Process Optimization of Electrospun PEEK-Sulfonated Nanofibers by Response Surface Methodology , 2015, Materials.

[70]  M. Matsusaki,et al.  Development of Endothelial Cell Networks in 3D Tissues by Combination of Melt Electrospinning Writing with Cell-Accumulation Technology. , 2018, Small.

[71]  W. Cong,et al.  Additive manufacturing of carbon fiber reinforced thermoplastic composites using fused deposition modeling , 2015 .

[72]  E. Ahmadi,et al.  Melt electrospinning process optimization of polylactic acid nanofibers , 2016 .

[73]  K. Lozano,et al.  Nanofiber-reinforced polymers prepared by fused deposition modeling , 2003 .

[74]  Federica Chiellini,et al.  Melt electrospinning of polycaprolactone and its blends with poly(ethylene glycol) , 2010 .

[75]  J. Malda,et al.  Mechanical behavior of a soft hydrogel reinforced with three-dimensional printed microfibre scaffolds , 2018, Scientific Reports.

[76]  Tao Xu,et al.  Three dimensional electrospun PCL/PLA blend nanofibrous scaffolds with significantly improved stem cells osteogenic differentiation and cranial bone formation. , 2017, Biomaterials.

[77]  J. Groll,et al.  High definition fibrous poly(2-ethyl-2-oxazoline) scaffolds through melt electrospinning writing , 2014 .

[78]  Kevin M. Shakesheff,et al.  Tissue engineering: strategies, stem cells and scaffolds , 2008, Journal of anatomy.

[79]  Dietmar W. Hutmacher,et al.  Enhancing structural integrity of hydrogels by using highly organised melt electrospun fibre constructs , 2015 .

[80]  Dietmar W Hutmacher,et al.  Direct Writing By Way of Melt Electrospinning , 2011, Advanced materials.

[81]  P. Dalton,et al.  Melt electrowriting below the critical translation speed to fabricate crimped elastomer scaffolds with non-linear extension behaviour mimicking that of ligaments and tendons. , 2018, Acta biomaterialia.

[82]  Toby Brown,et al.  Poly(ε-caprolactone) Scaffolds Fabricated by Melt Electrospinning for Bone Tissue Engineering , 2016, Materials.

[83]  Jun Zeng,et al.  Fabrication of microfluidic channels based on melt-electrospinning direct writing , 2018 .

[84]  Keita Ito,et al.  Melt Electrowriting Allows Tailored Microstructural and Mechanical Design of Scaffolds to Advance Functional Human Myocardial Tissue Formation , 2018, Advanced Functional Materials.

[85]  Dietmar W. Hutmacher,et al.  A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate. , 2014, Acta biomaterialia.

[86]  D. Hutmacher,et al.  Chapter 6:Design and Fabrication of Scaffolds via Melt Electrospinning for Applications in Tissue Engineering , 2015 .

[87]  Martin Möller,et al.  Electrospinning of polymer melts: Phenomenological observations , 2007 .

[88]  Seeram Ramakrishna,et al.  Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds. , 2005, Journal of biomedical materials research. Part B, Applied biomaterials.

[89]  D. Hoey,et al.  Mediating human stem cell behaviour via defined fibrous architectures by melt electrospinning writing. , 2018, Acta biomaterialia.

[90]  J. Sanders,et al.  Fibro-porous meshes made from polyurethane micro-fibers: effects of surface charge on tissue response. , 2005, Biomaterials.

[91]  Sachiko Sukigara,et al.  Regeneration of Bombyx mori silk by electrospinning—part 1: processing parameters and geometric properties , 2003 .

[92]  P. Supaphol,et al.  Effects of solvents on electrospun polymeric fibers: preliminary study on polystyrene , 2004 .

[93]  Y. Long,et al.  Bubble Melt Electrospinning for Production of Polymer Microfibers , 2018, Polymers.

[94]  Fei Chen,et al.  Additive Manufacturing of a Photo-Cross-Linkable Polymer via Direct Melt Electrospinning Writing for Producing High Strength Structures. , 2016, Biomacromolecules.

[95]  S M Giannitelli,et al.  Current trends in the design of scaffolds for computer-aided tissue engineering. , 2014, Acta biomaterialia.

[96]  D. Hutmacher,et al.  Periosteum tissue engineering in an orthotopic in vivo platform. , 2017, Biomaterials.

[97]  Jos Malda,et al.  Reinforcement of hydrogels using three-dimensionally printed microfibres , 2015, Nature Communications.

[98]  Tong Lin,et al.  Needleless melt-electrospinning of polypropylene nanofibres , 2012 .

[99]  C. Xiaoqing,et al.  Efficient preparation of poly(lactic acid) nanofibers by melt differential electrospinning with addition of acetyl tributyl citrate , 2018 .

[100]  Amir A. Zadpoor,et al.  Additive Manufacturing of Biomaterials, Tissues, and Organs , 2016, Annals of Biomedical Engineering.

[101]  Miao Yu,et al.  Recent advances in melt electrospinning , 2016 .

[102]  D. Hutmacher,et al.  Endosteal-like extracellular matrix expression on melt electrospun written scaffolds. , 2017, Acta biomaterialia.

[103]  J. Malda,et al.  Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration. , 2019, Acta biomaterialia.

[104]  D. Cho,et al.  Fabrication of patterned nanofibrous mats using direct-write electrospinning. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[105]  Ernst Rank,et al.  Biofabricated soft network composites for cartilage tissue engineering , 2017, Biofabrication.

[106]  Tim R. Dargaville,et al.  Tailored Melt Electrowritten Scaffolds for the Generation of Sheet‐Like Tissue Constructs from Multicellular Spheroids , 2019, Advanced healthcare materials.

[107]  Ruggero Bettini,et al.  3D-printed chitosan-based scaffolds: An in vitro study of human skin cell growth and an in-vivo wound healing evaluation in experimental diabetes in rats. , 2018, Carbohydrate polymers.

[108]  P. Lelkes,et al.  Gradient porous fibrous scaffolds: a novel approach to improving cell penetration in electrospun scaffolds , 2018, Biomedical materials.

[109]  M. Yildiz,et al.  Modeling 3D melt electrospinning writing by response surface methodology , 2018, Materials & Design.

[110]  A. Mikos,et al.  Electrospinning of polymeric nanofibers for tissue engineering applications: a review. , 2006, Tissue engineering.

[111]  U. Müller-Richter,et al.  A new multilayered membrane for tissue engineering of oral hard- and soft tissue by means of melt electrospinning writing and film casting - An in vitro study. , 2019, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[112]  Y. Joo,et al.  Modeling of non-isothermal polymer jets in melt electrospinning , 2008 .

[113]  Fucheng Zhang,et al.  A Fundamental Study of Charge Effects on Melt Electrowritten Polymer Fibers , 2019, Materials & Design.

[114]  Dietmar W. Hutmacher,et al.  A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone , 2014, Disease Models & Mechanisms.

[115]  I Zein,et al.  Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. , 2001, Journal of biomedical materials research.

[116]  S. Hsu,et al.  Biodegradable polymer scaffolds. , 2016, Journal of materials chemistry. B.

[117]  Koji Nakane,et al.  Poly(ethylene‐co‐vinyl alcohol) and Nylon 6/12 nanofibers produced by melt electrospinning system equipped with a line‐like laser beam melting device , 2010 .

[118]  D. Hutmacher,et al.  Biologically Inspired Scaffolds for Heart Valve Tissue Engineering via Melt Electrowriting. , 2019, Small.

[119]  Dietmar W. Hutmacher,et al.  Design and Development of a Three-Dimensional Printing High-Throughput Melt Electrowriting Technology Platform , 2019, 3D Printing and Additive Manufacturing.