On the minimum number of recombination events in the evolutionary history of DNA sequences
暂无分享,去创建一个
In representing the evolutionary history of a set of binary DNA sequences by a connected graph, a set theoretical approach is introduced for studying recombination events. We show that set theoretical constraints have direct implications on the number of recombination events. We define a new lower bound on the number of recombination events and demonstrate the usefulness of our new approach through several explicit examples.
[1] M. Kreitman,et al. Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster , 1983, Nature.
[2] R. Hudson,et al. Statistical properties of the number of recombination events in the history of a sample of DNA sequences. , 1985, Genetics.
[3] R. Griffiths,et al. Bounds on the minimum number of recombination events in a sample history. , 2003, Genetics.
[4] J. Hein. A heuristic method to reconstruct the history of sequences subject to recombination , 1993, Journal of Molecular Evolution.