Effect of absence of cochlear outer hair cells on behavioural auditory threshold

THE function of the two populations of sensory cells in the mammalian inner ear is not well understood. Anatomical evidence indicates that the inner hair cells (IHCs) and the outer hair cells (OHCs) play separate roles in the transduction of acoustic stimuli1. Furthermore, there have been numerous proposals attributing different roles to the two hair cell populations in the production of the various cochlear potentials2–5. On the other hand, theoretical considerations and the interpretation of data from several experiments have led to suggestions of different types of interaction between the OHCs and IHCs6–8.

[1]  Ernst Terhardt,et al.  Facts and Models in Hearing , 1974 .

[2]  J. Wersäll PROBLEMS AND PITFALLS IN STUDIES OF COCHLEAR HAIR CELL PATHOLOGY , 1973 .

[3]  H. Spoendlin Neuroanatomy of the Cochlea , 1974 .

[4]  P. Dallos,et al.  Bioelectric correlates of kanamycin intoxication. , 1974, Audiology : official organ of the International Society of Audiology.

[5]  H. Spoendlin,et al.  THE INNERVATION OF THE COCHLEAR RECEPTOR , 1973 .

[6]  E. F. Evans,et al.  Auditory Frequency Selectivity and the Cochlear Nerve , 1974 .

[7]  J. Mills,et al.  Anatomical, behavioral, and electrophysiological observations on chinchillas after long exposures to noise. , 1973, Advances in Oto-Rhino-Laryngology.

[8]  Peter Dallos,et al.  Cochlear Inner and Outer Hair Cells: Functional Differences , 1972, Science.

[9]  H. Davis,et al.  Modification of cochlear potentials produced by streptomycin poisoning and by extensive venous obstruction , 1958, The Laryngoscope.

[10]  G. Bredberg,et al.  Effects of intense auditory stimulation: hearing losses and inner ear changes in the chinchilla. , 1974, The Journal of the Acoustical Society of America.

[11]  Alexander Joseph Book reviewDischarge patterns of single fibers in the cat's auditory nerve: Nelson Yuan-Sheng Kiang, with the assistance of Takeshi Watanabe, Eleanor C. Thomas and Louise F. Clark: Research Monograph no. 35. Cambridge, Mass., The M.I.T. Press, 1965 , 1967 .

[12]  P. A. Lynn,et al.  Cochlear innervation, signal processing, and their relation to auditory time-intensity effects. , 1970, The Journal of the Acoustical Society of America.

[13]  W. Saunders,et al.  Structural Pattern of the Organ of Corti. , 1967 .

[14]  J. Zwislocki,et al.  Neuro-Mechanical Frequency Analysis in the Cochlea , 1974 .

[15]  Aage R. Møller,et al.  Basic Mechanisms in Hearing , 1973 .

[16]  James D. Miller Audibility curve of the chinchilla , 1970 .