3-Deazaadenosine, a S-Adenosylhomocysteine Hydrolase Inhibitor, Has Dual Effects on NF-κB Regulation
暂无分享,去创建一个
Jeong-Hwa Lee | Ho-Shik Kim | Seong-Yun Jeong | In-Kyung Kim | Sang‐Gun Ahn | H. Rhim | Seong-Whan Jeong | J. Kim | Jin-Woo Kim
[1] U. Moens,et al. Effects of 3-deazaadenosine on apoptosis-related gene transcripts in HL-60 cells. , 1997, Pharmacology & toxicology.
[2] Mike Rothe,et al. IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK , 1997 .
[3] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[4] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[5] David M. Rothwarf,et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.
[6] K. Schulze-Osthoff,et al. Activation of Transcription Factor NF-κB and p38 Mitogen-activated Protein Kinase Is Mediated by Distinct and Separate Stress Effector Pathways* , 1997, The Journal of Biological Chemistry.
[7] H. Erdjument-Bromage,et al. The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism , 1997, Cell.
[8] A. Israël,et al. I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF‐κB activity , 1997 .
[9] P. Chiang,et al. Apoptosis of L1210 Leukemia Cells Induced by 3-Deazaadenosine Analogs: Differential Expression of c-myc, NF-Kappa B and Molecular Events. , 1997, Journal of biomedical science.
[10] I. Kim,et al. 3‐deazaadenosine analogues inhibit the production of tumour necrosis factor‐α in RAW264.7 cells stimulated with lipopolysaccharide , 1996, Immunology.
[11] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[12] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[13] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[14] D. White,et al. Rel/NF-kappaB/IkappaB proteins and cancer. , 1996, Oncogene.
[15] Nigel Mackman,et al. Elevated Cyclic AMP Inhibits NF-κB-mediated Transcription in Human Monocytic Cells and Endothelial Cells* , 1996, The Journal of Biological Chemistry.
[16] L. Ignarro,et al. Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[17] E M Schwarz,et al. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. , 1995, Genes & development.
[18] A. Baldwin,et al. Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids , 1995, Science.
[19] Joseph A. DiDonato,et al. Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis , 1995, Science.
[20] David Baltimore,et al. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB , 1995, Nature.
[21] D. Burke,et al. Anti-human immunodeficiency virus 1 (HIV-1) activities of 3-deazaadenosine analogs: increased potency against 3'-azido-3'-deoxythymidine-resistant HIV-1 strains. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[22] C. Scheidereit,et al. Activation of NF‐kappa B in vivo is regulated by multiple phosphorylations. , 1994, The EMBO journal.
[23] S. Ghosh,et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. , 1994, Science.
[24] I. Verma,et al. Autoregulation of I kappa B alpha activity. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[25] T. Eide,et al. Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine. , 1993, Biochemical pharmacology.
[26] J. A. Duerre,et al. Effect of methylation inhibitors on gene expression in HL-60 cells. , 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[27] C. A. de la Motte,et al. 3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells. , 1992, The Journal of biological chemistry.
[28] D. Männel,et al. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells , 1992, The Journal of experimental medicine.
[29] C. Flexner,et al. 3-deaza-adenosine and inhibition of HIV , 1992, The Lancet.
[30] P. Baeuerle,et al. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1. , 1991, The EMBO journal.
[31] G. Sonenshein,et al. Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[32] B. E. Huber,et al. 3-deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells. , 1990, Journal of immunology.
[33] C V Jongeneel,et al. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages , 1990, The Journal of experimental medicine.
[34] D. Baltimore,et al. The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction , 1989, Cell.
[35] G. Nabel,et al. An inducible transcription factor activates expression of human immunodeficiency virus in T cells , 1987, Nature.
[36] P. Chomczyński,et al. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.
[37] P. Backlund,et al. Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis. , 1986, European journal of biochemistry.
[38] R. Roeder,et al. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.
[39] W. Falk,et al. Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. , 1982, The Journal of biological chemistry.
[40] P. Chiang,et al. Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo. , 1979, Biochemical pharmacology.
[41] G. S. Duncan,et al. Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: evidence for a methylation reaction essential to cytolysis. , 1978, Proceedings of the National Academy of Sciences of the United States of America.
[42] P. Chiang,et al. S-Adenosyl-L-homocysteine hydrolase: analogues of S-adenosyl-L-homocysteine as potential inhibitors. , 1977, Molecular pharmacology.
[43] M J May,et al. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.
[44] A. Baldwin,et al. THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .
[45] P. Baeuerle,et al. Function and activation of NF-kappa B in the immune system. , 1994, Annual review of immunology.
[46] R. Crouch,et al. Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents. , 1986, Journal of medicinal chemistry.
[47] G. Elion,et al. Immunosuppressive effects of the S-adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine. , 1982, Journal of immunopharmacology.