Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

The mechanisms underpinning concussion, traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE) are poorly understood. Using neuropathological analyses of brains from teenage athletes, a new mouse model of concussive impact injury, and computational simulations, Tagge et al. show that head injuries can induce TBI and early CTE pathologies independent of concussion.

Robin O Cleveland | Janusz Konrad | Yorghos Tripodis | Alon Friedman | Ann C McKee | Maria Ericsson | Ronel Veksler | Patric K Stanton | Thor D Stein | Robert C Cantu | J. Konrad | P. Stanton | D. Kaufer | R. Ransohoff | A. McKee | R. Cantu | C. Nowinski | R. Cleveland | N. Kowall | Xiao Zhen Zhou | K. Lu | G. Howell | B. Lamb | M. Ericsson | L. Goldstein | J. Hamilton | Y. Tripodis | T. Stein | A. Friedman | N. Hua | V. Senatorov | V. Alvarez | G. Hall | Haiyan Lu | Amanda Gaudreau-Balderrama | J. Moncaster | Juliet A Moncaster | Mark W Wojnarowicz | Lee E Goldstein | Andrew M Fisher | Chad A Tagge | Chirag Upreti | Noel Casey | Christopher J Nowinski | Neil W Kowall | Sudad Saman | Garth F Hall | William C Moss | Richard M Ransohoff | Chad A. Tagge | Andrew M. Fisher | O. Minaeva | Xiao‐lei Zhang | Mark W. Wojnarowicz | N. Casey | O. Kokiko-Cochran | Sudad Saman | K. Onos | R. Veksler | A. Kondo | Omid Miry | L. R. Vose | Katisha R. Gopaul | C. Upreti | Audrey M Hildebrandt | Erich S. Franz | A. Anderson | B. Huber | William C. Moss | James A Hamilton | Ning Hua | Olga N Kokiko-Cochran | Bruce T Lamb | Haiyan Lu | Gareth R Howell | Daniela Kaufer | Asami Kondo | Christopher J. Nowinski | Bertrand R Huber | Vladimir V Senatorov | Xiao-Lei Zhang | Victor E. Alvarez | Olga V Minaeva | Amanda Gaudreau-Balderrama | Kristen D Onos | Xiao Z Zhou | Omid Miry | Linnea R Vose | Katisha R Gopaul | Victor E Alvarez | Erich S Franz | Andrew T Anderson | Kun P Lu | A. Mckee | Yorghos Tripodis | Linnea R. Vose

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