Complex background suppression for vibro-acoustography images.

Vibro-acoustography (VA) is an ultrasound-based imaging modality that maps the acoustic response, or acoustic emission, of an object stimulated by two ultrasound waves at slightly different frequencies. VA images typically have a nonzero background intensity which can reduce contrast in images. We present a method that uses the complex representation of the acoustic emission data to estimate and suppress the unwanted background signal. This method utilizes a fast, linear approach to the problem called complex background suppression (CBS) using a square filtering window of size W×W. Images processed with the CBS algorithm have significantly enhanced contrast. Another improvement observed with this method is the ability to better localize objects within the depth direction with respect to the ultrasound transducer. This algorithm was tested on images obtained from scanning a phantom with spherical inclusions, a urethane breast phantom, and in vivo human breast. The results show that image quality is improved through processing with the CBS algorithm by increasing the contrast of features in the images. The contrast in the sphere phantom was increased by factors of 2-12 depending on the sphere. Utilizing the CBS algorithm increased the contrast in breast phantom by factors ranging from 1.1 to 5.4 for various inclusions. The size of the filtering window, W, affected the contrast achieved between the phantom features such as the spheres or simulated inclusions and the background material. Application of the CBS algorithm also demonstrated that objects could be localized in depth much better as the relationship to image intensity level was directly correlated to objects located at the center of the focal plane in the axial direction. This method has wide applicability for all VA imaging applications.

[1]  A. L. Thuras,et al.  Extraneous Frequencies Generated in Air Carrying Intense Sound Waves , 1934 .

[2]  James F. Greenleaf,et al.  Vibro-acoustic tissue mammography , 2002, IEEE Transactions on Medical Imaging.

[3]  Mostafa Fatemi,et al.  A Review of Vibro-acoustography and its Applications in Medicine. , 2011, Current medical imaging reviews.

[4]  J F Greenleaf,et al.  Vibro-acoustography: an imaging modality based on ultrasound-stimulated acoustic emission. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[5]  M. Fatemi,et al.  Comparison of stress field forming methods for vibro-acoustography , 2004, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[6]  Mostafa Fatemi,et al.  Critical issues in breast imaging by vibro-acoustography. , 2006, Ultrasonics.

[7]  J F Greenleaf,et al.  Probing the dynamics of tissue at low frequencies with the radiation force of ultrasound. , 2000, Physics in medicine and biology.

[8]  Mostafa Fatemi,et al.  Breast vibro-acoustography: initial results show promise , 2012, Breast Cancer Research.

[9]  A.C. Frery,et al.  Stress field forming of sector array transducers for vibro-acoustography , 2005, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[10]  R. Bracewell The Fourier Transform and Its Applications , 1966 .

[11]  Farid G. Mitri,et al.  Improved vibroacoustography imaging for nondestructive inspection of materials , 2005 .

[12]  James F. Greenleaf,et al.  Multifrequency vibro-acoustography , 2006, IEEE Transactions on Medical Imaging.

[13]  James F. Greenleaf,et al.  In vivo thyroid vibro-acoustography: a pilot study , 2013, BMC Medical Imaging.

[14]  Glauber T Silva,et al.  Parametric amplification of the dynamic radiation force of acoustic waves in fluids. , 2006, Physical review letters.

[15]  Mostafa Fatemi,et al.  Application of vibro-acoustography in prostate tissue imaging. , 2013, Medical physics.

[16]  M. Fatemi,et al.  Vibro-acoustography and multifrequency image compounding. , 2011, Ultrasonics.

[17]  Farid G. Mitri,et al.  Surface roughness imaging using the acoustic emission induced by the dynamic radiation force of ultrasound , 2006 .

[18]  J. Greenleaf,et al.  Ultrasound-stimulated vibro-acoustic spectrography. , 1998, Science.

[19]  J F Greenleaf,et al.  Vibro-acoustography imaging of permanent prostate brachytherapy seeds in an excised human prostate--preliminary results and technical feasibility. , 2009, Ultrasonics.

[20]  James F. Greenleaf,et al.  Performance of vibro-acoustography in detecting microcalcifications in excised human breast tissue: a study of 74 tissue samples , 2004, IEEE Transactions on Medical Imaging.

[21]  James F. Greenleaf,et al.  Imaging mass lesions by vibro-acoustography: modeling and experiments , 2004, IEEE Transactions on Medical Imaging.

[22]  Rayette Fisher,et al.  Hybrid beamforming and steering with reconfigurable arrays , 2010, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[23]  Mostafa Fatemi,et al.  Linear Arrays for Vibro-Acoustography: A Numerical Simulation Study , 2004, Ultrasonic imaging.

[24]  Glauber T Silva,et al.  Difference-frequency generation in vibro-acoustography , 2011, Physics in medicine and biology.

[25]  Mostafa Fatemi,et al.  In Vivo Vibroacoustography of Large Peripheral Arteries , 2008, Investigative radiology.

[26]  K. Boone,et al.  Effect of skin impedance on image quality and variability in electrical impedance tomography: a model study , 1996, Medical and Biological Engineering and Computing.

[27]  Mostafa Fatemi,et al.  Image formation in vibro-acoustography with depth-of-field effects , 2006, Comput. Medical Imaging Graph..

[28]  P. J. Westervelt,et al.  Scattering of Sound by Sound , 1957 .

[29]  James F. Greenleaf,et al.  Implementation of vibro-acoustography on a clinical ultrasound system , 2010, 2010 IEEE International Ultrasonics Symposium.

[30]  James F. Greenleaf,et al.  Prostate Cryotherapy Monitoring Using Vibroacoustography: Preliminary Results of an Ex Vivo Study and Technical Feasibility , 2008, IEEE Transactions on Biomedical Engineering.

[31]  J. Jensen,et al.  Calculation of pressure fields from arbitrarily shaped, apodized, and excited ultrasound transducers , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.