Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture.
暂无分享,去创建一个
M. Bown | R. Sayers | A. Naylor | T. Robinson | B. Vijaynagar | D. Moore | M. Salem | K. West
[1] J David Spence,et al. Asymptomatic carotid stenosis. , 2013, Circulation.
[2] A. Gabrielsen,et al. Correlations between clinical variables and gene-expression profiles in carotid plaque instability. , 2011, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[3] R. Sayers,et al. Dual antiplatelet therapy prior to carotid endarterectomy reduces post-operative embolisation and thromboembolic events: post-operative transcranial Doppler monitoring is now unnecessary. , 2010, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[4] T. Lehtimäki,et al. Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques—Tampere Vascular Study , 2010, Annals of medicine.
[5] Robert A Hegele,et al. Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. , 2010, Archives of neurology.
[6] N. Rudarakanchana,et al. Asymptomatic Carotid Surgery Trial-2 (ACST-2): rationale for a randomised clinical trial comparing carotid endarterectomy with carotid artery stenting in patients with asymptomatic carotid artery stenosis. , 2009, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[7] G. Hunter,et al. Integrin and matrix metalloproteinase expression in human carotid plaque. , 2009, The Journal of surgical research.
[8] M. Daemen,et al. Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery. , 2007, Physiological genomics.
[9] S. Tonstad,et al. Increased Expression of Visfatin in Macrophages of Human Unstable Carotid and Coronary Atherosclerosis: Possible Role in Inflammation and Plaque Destabilization , 2007, Circulation.
[10] M. Kaste,et al. Microarray Analysis Reveals Overexpression of CD163 and HO-1 in Symptomatic Carotid Plaques , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[11] Alberto Smith,et al. Novel Candidate Genes in Unstable Areas of Human Atherosclerotic Plaques , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[12] R. Dempsey,et al. Increased Angiogenesis and Angiogenic Gene Expression in Carotid Artery Plaques from Symptomatic Stroke Patients , 2006, Neurosurgery.
[13] R. Dempsey,et al. Increased expression of genes that control ionic homeostasis, second messenger signaling and metabolism in the carotid plaques from patients with symptomatic stroke , 2006, Journal of neurochemistry.
[14] R. Dempsey,et al. Carotid atherosclerotic plaques from symptomatic stroke patients share the molecular fingerprints to develop in a neoplastic fashion: A microarray analysis study , 2005, Neuroscience.
[15] P. Rothwell,et al. Histological Correlates of Carotid Plaque Surface Morphology on Lumen Contrast Imaging , 2004, Circulation.
[16] D. Schrijvers,et al. Gene Expression Profiling of Apoptosis-Related Genes in Human Atherosclerosis: Upregulation of Death-Associated Protein Kinase , 2002, Arteriosclerosis, thrombosis, and vascular biology.
[17] Jason E. Stewart,et al. Minimum information about a microarray experiment (MIAME)—toward standards for microarray data , 2001, Nature Genetics.
[18] Richard T. Lee,et al. Overexpression of Eotaxin and the CCR3 Receptor in Human Atherosclerosis: Using Genomic Technology to Identify a Potential Novel Pathway of Vascular Inflammation , 2000, Circulation.
[19] M. Eliasziw,et al. The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. , 2000, The New England journal of medicine.
[20] M. Eliasziw,et al. Causes and severity of ischemic stroke in patients with internal carotid artery stenosis. , 2000, JAMA.
[21] P. Sandercock,et al. Recently occluded intracranial and extracranial carotid arteries. Relevance of the unstable atherosclerotic plaque. , 1999, Stroke.
[22] W D Wagner,et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[23] G. Sicard. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70–99%) or mild (0–29%) carotid stenosis: European Carotid Surgery Trialist' Collaborative Group. Lancet 1991;337:1235-43 , 1992 .
[24] A. Buchan,et al. *North American Symptomatic Carotid Endarterectomy Trial (NASCET) Steering Committee. Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis. , 1991 .
[25] D. Sackett,et al. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.
[26] C. Warlow,et al. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis , 1991, The Lancet.
[27] C. Zarins,et al. Critical carotid stenoses: morphologic and chemical similarity between symptomatic and asymptomatic plaques. , 1989, Journal of vascular surgery.
[28] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[29] D. Ratliff,et al. A comparison of quality control methods applied to carotid endarterectomy. , 1996, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.