A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism
暂无分享,去创建一个
E. Trabetti | P. Pignatti | D. Girelli | O. Olivieri | N. Martinelli | P. Pignatti | S. Friso | R. Corrocher | E. Tinazzi | G. Faccini | C. Stranieri
[1] H. Blom,et al. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk , 2001, Journal of Molecular Medicine.
[2] O. Aras,et al. C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease. , 2001, Clinical chemistry.
[3] G. M. Taylor,et al. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[4] V. Gudnason,et al. The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study. , 2001, Atherosclerosis.
[5] G. Wells,et al. Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations. , 2000, American journal of human genetics.
[6] W. Hörl,et al. Effect of MTHFR 1298A-->C and MTHFR 677C-->T genotypes on total homocysteine, folate, and vitamin B(12) plasma concentrations in kdiney graft recipients. , 2000, Journal of the American Society of Nephrology : JASN.
[7] Y. Friedlander,et al. The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients. , 2000, The Journal of nutrition.
[8] D. Girelli,et al. Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease. , 2000, The New England journal of medicine.
[9] S. Vollset,et al. The controversy over homocysteine and cardiovascular risk. , 2000, The American journal of clinical nutrition.
[10] D. Quilliot,et al. The effect of 677C-->T and 1298A-->C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects. , 2000, The British journal of nutrition.
[11] T. Marquardt,et al. Linkage disequilibrium of the common mutations 677C > T and 1298A > C of the human methylenetetrahydrofolate reductase gene as proven by the novel polymorphisms 129C > T, 1068C > T , 2000, European Journal of Pediatrics.
[12] J. G. Donnelly. The 1298(A-->C) mutation of methylenetetrahydrofolate reductase should be designated to the 1289 position of the gene. , 2000, American journal of human genetics.
[13] H. Blom,et al. Reply to Donnelly , 2000 .
[14] A. Ziegler,et al. Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects(NTD). , 1999, American journal of medical genetics.
[15] G. Morgan,et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[16] R. Matalon,et al. Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population. , 1999, American journal of medical genetics.
[17] Y. Friedlander,et al. A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations. , 1999, The Journal of nutrition.
[18] G. Hankey,et al. Homocysteine and vascular disease , 1999, The Lancet.
[19] L. Brudin,et al. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. , 1998, Circulation.
[20] R. Rozen,et al. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. , 1998, Molecular genetics and metabolism.
[21] E. Trabetti,et al. Methylenetetrahydrofolate reductase C677T mutation, plasma homocysteine, and folate in subjects from northern Italy with or without angiographically documented severe coronary atherosclerotic disease: evidence for an important genetic-environmental interaction. , 1998, Blood.
[22] F. Gabreëls,et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? , 1998, American journal of human genetics.
[23] E. Sacchi,et al. High Frequency of the C677T Mutation in the Methylenetetrahydrofolate Reductase (MTHFR) Gene in Northern Italy , 1997, Thrombosis and Haemostasis.
[24] R. Rozen. Genetic Predisposition to Hyperhomocysteinemia: Deficiency of Methylenetetrahydrofolate Reductase (MTHFR) , 1997, Thrombosis and Haemostasis.
[25] A. Viel,et al. Loss of heterozygosity at the 5,10-methylenetetrahydrofolate reductase locus in human ovarian carcinomas. , 1997, British Journal of Cancer.
[26] P. Frosst,et al. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. , 1997, Arteriosclerosis, thrombosis, and vascular biology.
[27] W. Willett,et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. , 1996, Circulation.
[28] M. Margaglione,et al. Elevated total plasma homocysteine and 677C-->T mutation of the 5,10-methylenetetrahydrofolate reductase gene in thrombotic vascular disease. , 1996, American journal of human genetics.
[29] P. Wilson,et al. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. , 1993, JAMA.
[30] E. Falk,et al. Homocysteine and atherothrombosis , 2001, Lipids.
[31] W. Hörl,et al. Effect of MTHFR 1298 A 3 C and MTHFR 677 C 3 T Genotypes on Total Homocysteine , Folate , and Vitamin B 12 Plasma Concentrations in Kidney Graft Recipients , 2000 .
[32] R. Matthews,et al. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia , 1999, Nature Structural Biology.
[33] J. Selhub,et al. Homocysteine and thrombotic disease. , 1997, Blood.
[34] I. Rosenberg,et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. , 1996, Circulation.
[35] R. Matthews,et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase , 1995, Nature Genetics.
[36] Y. Sako,et al. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. , 1987, Journal of chromatography.