Second generation immune networks.

[1]  F. Melchers,et al.  Inhibition of mitogenic stimulation of mouse lymphocytes by anti‐mouse immunoglobulin antibodies. I. Mode of action , 1974, European journal of immunology.

[2]  F. Melchers,et al.  Maturation of mitogen‐activated bone marrow‐derived lymphocytes in the absence of proliferation , 1974, European journal of immunology.

[3]  S. Avrameas,et al.  Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. , 1982, Journal of immunology.

[4]  F. Alt,et al.  Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines , 1984, Nature.

[5]  Robbert Benner,et al.  Isotypes and specificities of immunoglobulins produced by germ‐free mice fed chemically defined ultrafiltered “antigen‐free” diet , 1984, European journal of immunology.

[6]  D. Moras,et al.  Correlation between segmental mobility and the location of antigenic determinants in proteins , 1984, Nature.

[7]  A. Coutinho,et al.  Reactions among IgM antibodies derived from normal, neonatal mice , 1984, European journal of immunology.

[8]  Stephen Wolfram,et al.  Cellular automata as models of complexity , 1984, Nature.

[9]  A. Coutinho,et al.  The high idiotypic connectivity of “natural” newborn antibodies is not found in adult mitogen‐reactive B cell repertoires , 1986, European journal of immunology.

[10]  N. Shastri,et al.  Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation , 1986, Nature.

[11]  A. Coutinho,et al.  Lymphocyte Population Kinetics in the Mouse , 1986, Immunological reviews.

[12]  A. Coutinho,et al.  Autonomous activation of B and T cells in antigen‐free mice , 1986, European journal of immunology.

[13]  A. Coutinho,et al.  Immunocompetent autoreactive B lymphocytes are activated cycling cells in normal mice , 1986, The Journal of experimental medicine.

[14]  B. Bogen,et al.  Idiotope‐specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules , 1986, European journal of immunology.

[15]  J. Kearney,et al.  In vivo suppression of perinatal multispecific B cells results in a distortion of the adult B cell repertoire , 1986, European journal of immunology.

[16]  F. Alt,et al.  Development of the primary antibody repertoire. , 1987, Science.

[17]  D. Holmberg High connectivity, natural antibodies preferentially use 7183 and QUPC52 VH families , 1987, European journal of immunology.

[18]  Thomas L. Rothstein,et al.  The role of clonal selection and somatic mutation in autoimmunity , 1987, Nature.

[19]  C. Milstein,et al.  Mutation Drift and Repertoire Shift in the Maturation of the Immune Response , 1987, Immunological reviews.

[20]  A. Coutinho,et al.  Natural lymphocyte activation in postnatal development of germ-free and conventional mice. , 1988, Annales de l'Institut Pasteur. Immunology.

[21]  A. Coutinho,et al.  Inverse correlation between the utilization of an idiotype in specific immune responses and its representation in pre‐immune “natural” antibodies , 1988, European journal of immunology.

[22]  A S Perelson,et al.  Modeling adaptive biological systems. , 1989, Bio Systems.

[23]  A. Coutinho,et al.  Beyond Clonal Selection and Network , 1989, Immunological reviews.

[24]  D. Holmberg,et al.  Establishment and Functional Implications of B‐cell Connectivity , 1989, Immunological reviews.

[25]  F. Varela,et al.  Exploring the Meaning of Connectivity in the Immune Network , 1989, Immunological reviews.

[26]  F. Varela,et al.  The relationship between connectivity and tolerance as revealed by computer simulation of the immune network: some lessons for an understanding of autoimmunity. , 1989, Journal of autoimmunity.

[27]  A. Coutinho,et al.  Tolerize one, tolerize them all: tolerance is self-assertion. , 1989, Immunology today.

[28]  A. Perelson Immune Network Theory , 1989, Immunological reviews.

[29]  Pauline Hogeweg,et al.  Unreasonable implications of reasonable idiotypic network assumptions , 1989 .

[30]  P. Pereira,et al.  V-region connectivity in T cell repertoires. , 1989, Annual review of immunology.

[31]  M. Kazatchkine,et al.  Anti‐idiotypes against Autoantibodies in Normal Immunoglobulins: Evidence for Network Regulation of Human Autoimmune Responses , 1989, Immunological reviews.

[32]  Susumu Tonegawa,et al.  Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining , 1989, Cell.

[33]  F. Varela,et al.  Autoimmunity: the Moving Boundaries Between Physiology and Pathology , 1989 .

[34]  K. Rajewsky,et al.  Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B‐CLL progenitor generation. , 1990, The EMBO journal.

[35]  F. Varela,et al.  Dynamics of a class of immune networks. II. Oscillatory activity of cellular and humoral components. , 1990, Journal of theoretical biology.

[36]  Alan S. Perelson,et al.  A SIMPLE IDIOTYPIC NETWORK MODEL WITH COMPLEX DYNAMICS , 1990 .

[37]  L. Nelson,et al.  Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy , 1990, The Journal of experimental medicine.

[38]  R. Poljak,et al.  Three-dimensional structure of an idiotope–anti-idiotope complex , 1990, Nature.

[39]  M. Zöller Alteration of Idiotypic Connectivity in Prenatally Tolerized Neonatal Mice * , 1990, Scandinavian journal of immunology.

[40]  A. Rudensky,et al.  Immunoglobulin‐specific T‐B cell interaction. IV. B cell presentation of idiotypic determinant(s) of monoclonal anti‐surface immunoglobulin antibody to idiotope‐recognizing helper T clones , 1990, European journal of immunology.

[41]  F. Varela,et al.  Dynamics of a class of immune networks. I. Global stability of idiotype interactions. , 1990, Journal of theoretical biology.

[42]  A. Feeney,et al.  Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences , 1990, The Journal of experimental medicine.

[43]  S. Ohno Commentary on “The Protecton: The Evolutionarily Selected Unit of Humoral Immunity” , 1990, Immunological reviews.

[44]  D. Holmberg,et al.  Genetic basis of the neonatal antibody repertoire: germline V-gene expression and limited N-region diversity. , 1990, International immunology.