NF-κB1 p105 Negatively Regulates TPL-2 MEK Kinase Activity
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S. Smerdon | S. Gamblin | V. Lang | M. Belich | S. Ley | S. Beinke | J. Deka | P. Walker | S. Howell | S. Beinke | J. Deka | V. Lang | M. P. Belich | P. A. Walker | S. Howell | S. J. Smerdon | S. J. Gamblin | S. C. Ley | Philip A. Walker | Steven Howell | Steve Gamblin | S. Gamblin
[1] M. Belich,et al. The Death Domain of NF-κB1 p105 Is Essential for Signal-induced p105 Proteolysis* , 2002, The Journal of Biological Chemistry.
[2] S. Gerondakis,et al. The activity of a 70 kilodalton I kappa B molecule identical to the carboxyl terminus of the p105 NF-kappa B precursor is modulated by protein kinase A. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[3] Thomas Henkel,et al. Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κB subunit , 1992, Cell.
[4] M. Karin,et al. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. , 2000, Annual review of immunology.
[5] C. Scheidereit,et al. NF‐κB p105 is a target of IκB kinases and controls signal induction of Bcl‐3–p50 complexes , 1999 .
[6] W. Kolch,et al. Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP , 1999, Nature.
[7] Hideaki Ishikawa,et al. Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50 , 1998, The Journal of experimental medicine.
[8] P. Tsichlis,et al. Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[9] L. Johnston,et al. TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105 , 1999, Nature.
[10] N. Copeland,et al. Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation. , 1997, Genes & development.
[11] S. Aaronson,et al. Expression cDNA cloning of a serine kinase transforming gene. , 1993, Oncogene.
[12] Danielle Hulsman,et al. Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice , 2002, Nature Genetics.
[13] S. Ley,et al. S‐acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes , 1997, The EMBO journal.
[14] Sally J. Leevers,et al. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane , 1994, Nature.
[15] Anton Berns,et al. High-throughput retroviral tagging to identify components of specific signaling pathways in cancer , 2002, Nature Genetics.
[16] T. Akiyama,et al. The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation. , 1993, The Journal of biological chemistry.
[17] U. Sieben,et al. STRUCTURE, REGULATION AND FUNCTION OF NF-1d3 , 1994 .
[18] G. Kollias,et al. TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway , 2000, Cell.
[19] S. Harrison,et al. Structure of an IκBα/NF-κB Complex , 1998, Cell.
[20] D. Pappin,et al. Activation of MEK‐1 and SEK‐1 by Tpl‐2 proto‐oncoprotein, a novel MAP kinase kinase kinase. , 1996, The EMBO journal.
[21] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[22] R. Hay,et al. βTrCP-Mediated Proteolysis of NF-κB1 p105 Requires Phosphorylation of p105 Serines 927 and 932 , 2003, Molecular and Cellular Biology.
[23] David Baltimore,et al. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses , 1995, Cell.
[24] W. Greene,et al. The Proto-Oncogene Cot Kinase Participates in CD3/CD28 Induction of NF-κB Acting through the NF-κB-Inducing Kinase and IκB Kinases , 1999 .
[25] W. Kolch,et al. Mechanism of Suppression of the Raf/MEK/Extracellular Signal-Regulated Kinase Pathway by the Raf Kinase Inhibitor Protein , 2000, Molecular and Cellular Biology.
[26] J. Gutkind,et al. Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation , 2000, Molecular and Cellular Biology.
[27] Shao-Cong Sun,et al. NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase. , 2003, Molecular cell.
[28] A. Szabó,et al. Surface plasmon resonance and its use in biomolecular interaction analysis (BIA). , 1995, Current opinion in structural biology.
[29] D. Ballard,et al. Proteolytic Processing of NF-B/IB in Human Monocytes , 1995, The Journal of Biological Chemistry.
[30] Steve,et al. The Activity of a 70 Kilodalton 1 KB Molecule Identical to the Carboxyl Terminus of the p 105 NF-KB Precursor Is Modulated by Protein Kinase A ’ , 2005 .
[31] P. Tsichlis,et al. Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion , 1993, Journal of virology.
[32] G. Ghosh,et al. The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation , 1998, Cell.
[33] Michael Karin,et al. Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation , 1999 .
[34] G. Franzoso,et al. Structure, regulation and function of NF-kappa B. , 1994, Annual review of cell biology.
[35] A. Salmeron,et al. Direct Phosphorylation of NF-κB1 p105 by the IκB Kinase Complex on Serine 927 Is Essential for Signal-induced p105 Proteolysis* , 2001, The Journal of Biological Chemistry.
[36] P. Tsichlis,et al. Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase. , 1994, Proceedings of the National Academy of Sciences of the United States of America.