Clinical Application of Beryllium Lymphocyte Proliferation Testing

Because of its unique properties, beryllium has become widely used in a variety of industrial applications, including inertial guidance systems, turbine rotor blades, laser tubes, rocket engine liners, springs, aircraft brakes and landing gear, ball bearings, injection and blow mold tooling,

[1]  K. Kreiss,et al.  Racial differences in prevalence of a supratypic HLA-genetic marker immaterial to pre-employment testing for susceptibility to chronic beryllium disease. , 2002, American journal of industrial medicine.

[2]  M. Eisenbud,et al.  Origins of the standards for control of beryllium disease (1947-1949). , 1982, Environmental research.

[3]  H. Hardy,et al.  Delayed chemical pneumonitis occurring in workers exposed to beryllium compounds. , 1946, The Journal of industrial hygiene and toxicology.

[4]  B. Barna,et al.  Experimental beryllium-induced lung disease. I. Differences in immunologic responses to beryllium compounds in strains 2 and 13 guinea pigs. , 1984, International archives of allergy and applied immunology.

[5]  K. Kreiss,et al.  Machining risk of beryllium disease and sensitization with median exposures below 2 μg/m3 , 1996 .

[6]  M. Amicosante,et al.  HLA-DP-unrestricted TNF-α release in beryllium-stimulated peripheral blood mononuclear cells , 2002, European Respiratory Journal.

[7]  B. Barna,et al.  Immune mechanisms in beryllium lung disease. , 1991, Cleveland Clinic journal of medicine.

[8]  T. Robins,et al.  Is total mass or mass of alveolar-deposited airborne particles of beryllium a better predictor of the prevalence of disease? A preliminary study of a beryllium processing facility. , 2001, Applied occupational and environmental hygiene.

[9]  W. R. Williams,et al.  Development of beryllium lymphocyte transformation tests in chronic beryllium disease. , 1982, International archives of allergy and applied immunology.

[10]  K. Kreiss,et al.  Nonoccupational beryllium disease masquerading as sarcoidosis: identification by blood lymphocyte proliferative response to beryllium. , 1992, The American review of respiratory disease.

[11]  K. Kreiss,et al.  Pathologic and immunologic alterations in early stages of beryllium disease. Re-examination of disease definition and natural history. , 1989, The American review of respiratory disease.

[12]  J. Britz,et al.  Measurement of T-Lymphocyte Responses in Whole-Blood Cultures Using Newly Synthesized DNA and ATP , 2000, Clinical Diagnostic Laboratory Immunology.

[13]  M. Schlaak,et al.  Analysis of differentially regulated mRNAs in peripheral blood monocytes of berylliosis patients after in vitro stimulation , 2000, Journal of Molecular Medicine.

[14]  D. Monos,et al.  Human leukocyte antigen Class II amino acid epitopes: susceptibility and progression markers for beryllium hypersensitivity. , 2002, American journal of respiratory and critical care medicine.

[15]  B. Marrone,et al.  Beryllium sensitivity is linked to HLA-DP genotype. , 2001, Toxicology.

[16]  H. Hardy,et al.  Beryllium disease: The relation of pulmonary pathology to clinical course and prognosis based on a study of 130 cases from the U.S. Beryllium Case Registry , 1970 .

[17]  B. Barna,et al.  A study of the immunologic aspects of chronic berylliosis. , 1973, Chest.

[18]  B. Barna,et al.  Experimental beryllium-induced lung disease. II. Analyses of bronchial lavage cells in strains 2 and 13 guinea pigs. , 1984, International archives of allergy and applied immunology.

[19]  M. Cullen,et al.  Proliferative response of bronchoalveolar lymphocytes to beryllium. A test for chronic beryllium disease. , 1988, Annals of internal medicine.

[20]  N. Sprince,et al.  Reversible respiratory disease in beryllium workers. , 1978, The American review of respiratory disease.

[21]  D. Paustenbach,et al.  Identifying an apppropriate occupational exposure limit (OEL) for beryllium: data gaps and current research initiatives. , 2001, Applied occupational and environmental hygiene.

[22]  H. Wiedemann,et al.  Risks of beryllium disease related to work processes at a metal, alloy, and oxide production plant. , 1997, Occupational and environmental medicine.

[23]  L. Newman,et al.  Compartmentalized immune response reflects clinical severity of beryllium disease. , 1994, American journal of respiratory and critical care medicine.

[24]  P. S. White,et al.  Flow cytometry-based minisequencing: a new platform for high-throughput single-nucleotide polymorphism scoring. , 2000, Genomics.

[25]  M. Rossman,et al.  Bronchoalveolar lavage in a patient with chronic berylliosis: evidence for hypersensitivity pneumonitis. , 1982, Annals of internal medicine.

[26]  J. Hanifin,et al.  In vitro studies on granulomatous hypersensitivity to beryllium. , 1970, The Journal of investigative dermatology.

[27]  K. Kreiss,et al.  Machining risk of beryllium disease and sensitization with median exposures below 2 micrograms/m3. , 1996, American journal of industrial medicine.

[28]  L. Newman,et al.  Target organ localization of memory CD4(+) T cells in patients with chronic beryllium disease. , 2002, The Journal of clinical investigation.

[29]  W. R. Williams,et al.  Value of beryllium lymphocyte transformation tests in chronic beryllium disease and in potentially exposed workers , 1983, Thorax.

[30]  Daniel Vallero,et al.  Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001. , 2002, Environmental health perspectives.

[31]  M. Eisenbud,et al.  Epidemiological aspects of beryllium-induced nonmalignant lung disease: a 30-year update. , 1983, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[32]  L. Newman,et al.  Efficacy of Serial Medical Surveillance for Chronic Beryllium Disease in a Beryllium Machining Plant , 2001, Journal of occupational and environmental medicine.

[33]  G. Curtis Cutaneous hypersensitivity due to beryllium; a study of thirteen cases. , 1951, A.M.A. archives of dermatology and syphilology.

[34]  K. Kreiss,et al.  Screening blood test identifies subclinical beryllium disease. , 1989, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[35]  J. Stoeckle,et al.  Chronic beryllium disease. Long-term follow-up of sixty cases and selective review of the literature. , 1969, American Journal of Medicine.

[36]  H. Hardy BERYLLIUM CASE REGISTRY. , 1964, American journal of clinical pathology.

[37]  L. Newman,et al.  High Beryllium-stimulated TNF- α Is Associated with the − 308 TNF- α Promoter Polymorphism and with Clinical Severity in Chronic Beryllium Disease , 2001 .

[38]  R. Crystal,et al.  Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells. , 1989, The New England journal of medicine.

[39]  E. Frome,et al.  Identification of an abnormal beryllium lymphocyte proliferation test. , 2003, Toxicology.

[40]  R. Dweik,et al.  Nitric oxide attenuates beryllium-induced IFNgamma responses in chronic beryllium disease: evidence for mechanisms independent of IL-18. , 2002, Clinical immunology.

[41]  K. Kreiss,et al.  Epidemiology of beryllium sensitization and disease in nuclear workers. , 1993, The American review of respiratory disease.

[42]  M. McCawley,et al.  Beryllium sensitization and disease among long-term and short-term workers in a beryllium ceramics plant , 2001, International archives of occupational and environmental health.

[43]  L. Richeldi,et al.  HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. , 1993, Science.

[44]  D. Deubner,et al.  Variability, predictive value, and uses of the beryllium blood lymphocyte proliferation test (BLPT): preliminary analysis of the ongoing workforce survey. , 2001, Applied occupational and environmental hygiene.

[45]  T. N. Markham,et al.  Screening for chronic beryllium disease using beryllium specific lymphocyte proliferation testing , 1996, International archives of occupational and environmental health.

[46]  R. Dweik,et al.  Chronic beryllium disease , 2003 .

[47]  M R Cullen,et al.  Chronic beryllium disease in a precious metal refinery. Clinical epidemiologic and immunologic evidence for continuing risk from exposure to low level beryllium fume. , 2015, The American review of respiratory disease.

[48]  C. Tinelli,et al.  Major histocompatibility locus genetic markers of beryllium sensitization and disease. , 2001, The European respiratory journal.

[49]  K. Kreiss,et al.  Beryllium disease screening in the ceramics industry. Blood lymphocyte test performance and exposure-disease relations. , 1993, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[50]  Williams Wj,et al.  Development of beryllium lymphocyte transformation tests in chronic beryllium disease. , 1982 .

[51]  L. Richeldi,et al.  Interaction of genetic and exposure factors in the prevalence of berylliosis. , 1997, American Journal of Industrial Medicine.

[52]  M. Andrew,et al.  HLA-DPB1 and chronic beryllium disease: a HuGE review. , 2003, American journal of epidemiology.

[53]  K. Kreiss,et al.  Chronic beryllium disease--from the workplace to cellular immunology, molecular immunogenetics, and back. , 1994, Clinical immunology and immunopathology.