Bona Fide Predictions of Protein Secondary Structure Using Transparent Analyses of Multiple Sequence Alignments.

1. Protein Kinases (Catalytic Domain) 2761 2. The â Subunit of MoFe Nitrogenase 2763 3. The Hemorrhagic Metalloproteases 2765 B. Predicting Small Domains 2765 1. The Src Homology 3 (SH3) Domain 2765 2. The Src Homology 2 (SH2) Domain 2767 3. The Pleckstrin Homology Domain 2767 4. The Cyclin Family 2767 C. Predictions of Large Proteins 2768 1. Isopenicillin N Synthase 2768 2. Factor XIIIa 2771 3. The von Willebrand Factor A Domain 2773 4. Protein Tyrosine Phosphatase 2774 5. Protein Serine/Threonine Phosphatases 2774 6. The Proteasome 2775 D. The Critical Assessment of Structure Prediction (CASP1) Project 2780

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