A Rich1/Amot Complex Regulates the Cdc42 GTPase and Apical-Polarity Proteins in Epithelial Cells

[1]  D. Bilder,et al.  Endocytic control of epithelial polarity and proliferation in Drosophila , 2005, Nature Cell Biology.

[2]  L. Holmgren,et al.  Angiomotin Regulates Endothelial Cell-Cell Junctions and Cell Motility* , 2005, Journal of Biological Chemistry.

[3]  Klemens Rottner,et al.  Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. , 2005, Molecular biology of the cell.

[4]  K. Patrie.  Identification and characterization of a novel tight junction-associated family of proteins that interacts with a WW domain of MAGI-1. , 2005, Biochimica et biophysica acta.

[5]  B. Margolis,et al.  Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells , 2005, Journal of Cell Science.

[6]  P. Belleau,et al.  Protein diversity is generated within the motin family of proteins by alternative pre-mRNA splicing. , 2005, Gene.

[7]  A. Nusrat,et al.  Endocytosis of the apical junctional complex: mechanisms and possible roles in regulation of epithelial barriers , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.

[8]  Borivoj Vojnovic,et al.  Spatially Distinct Binding of Cdc42 to PAK1 and N-WASP in Breast Carcinoma Cells , 2005, Molecular and Cellular Biology.

[9]  B. Margolis,et al.  PATJ regulates tight junction formation and polarity in mammalian epithelial cells , 2005, The Journal of cell biology.

[10]  C. Der,et al.  GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors , 2005, Nature Reviews Molecular Cell Biology.

[11]  Shinya Kuroda,et al.  Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. , 2004, Developmental cell.

[12]  A. Hopkins,et al.  RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. , 2004, American journal of physiology. Cell physiology.

[13]  K. Farsad,et al.  RICH-1 has a BIN/Amphiphysin/Rvsp domain responsible for binding to membrane lipids and tubulation of liposomes. , 2004, Biochemical and biophysical research communications.

[14]  T. Hurd,et al.  Tight Junction Protein Par6 Interacts with an Evolutionarily Conserved Region in the Amino Terminus of PALS1/Stardust* , 2004, Journal of Biological Chemistry.

[15]  Joerg Betschinger,et al.  Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. , 2004, Developmental cell.

[16]  Samuel W Straight,et al.  Loss of PALS1 expression leads to tight junction and polarity defects. , 2004, Molecular biology of the cell.

[17]  J. Arbiser,et al.  Angiomotin expression promotes hemangioendothelioma invasion , 2004, Oncogene.

[18]  I. Macara.  Par Proteins: Partners in Polarization , 2004, Current Biology.

[19]  B. Peter,et al.  BAR Domains as Sensors of Membrane Curvature: The Amphiphysin BAR Structure , 2004, Science.

[20]  Amy S. Gladfelter,et al.  Scaffold-mediated symmetry breaking by Cdc42p , 2003, Nature Cell Biology.

[21]  B. Margolis,et al.  Composition and function of PDZ protein complexes during cell polarization. , 2003, American journal of physiology. Renal physiology.

[22]  M. Matsuda,et al.  Activity of Rho-family GTPases during cell division as visualized with FRET-based probes , 2003, The Journal of cell biology.

[23]  B. Margolis,et al.  The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells , 2003, Journal of Cell Science.

[24]  Nicholas J. Hutchings,et al.  Linking the T Cell Surface Protein CD2 to the Actin-capping Protein CAPZ via CMS and CIN85* , 2003, Journal of Biological Chemistry.

[25]  S. Narumiya,et al.  Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. , 2003, Developmental cell.

[26]  R. Behringer,et al.  Angiomotin Regulates Visceral Endoderm Movements during Mouse Embryogenesis , 2003, Current Biology.

[27]  T. Pawson,et al.  A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl , 2003, Nature Cell Biology.

[28]  I. Macara,et al.  Structure of Cdc42 in a complex with the GTPase‐binding domain of the cell polarity protein, Par6 , 2003, The EMBO journal.

[29]  M. Monden,et al.  Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse* , 2003, The Journal of Biological Chemistry.

[30]  Catherine H. Wu,et al.  Human RhoGAP domain‐containing proteins: structure, function and evolutionary relationships , 2002, FEBS letters.

[31]  M. Matsuda,et al.  Activation of Rac and Cdc42 Video Imaged by Fluorescent Resonance Energy Transfer-Based Single-Molecule Probes in the Membrane of Living Cells , 2002, Molecular and Cellular Biology.

[32]  B. Margolis,et al.  The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost , 2002, The Journal of cell biology.

[33]  Giorgio F. Gilestro,et al.  The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met , 2002, Nature.

[34]  I. Dikic,et al.  Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors , 2002, Nature.

[35]  Y. Ono,et al.  JEAP, a Novel Component of Tight Junctions in Exocrine Cells* , 2002, The Journal of Biological Chemistry.

[36]  P. Aspenström,et al.  RICH, a Rho GTPase-activating Protein Domain-containing Protein Involved in Signaling by Cdc42 and Rac1* , 2001, The Journal of Biological Chemistry.

[37]  G. Apodaca,et al.  Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized Madin-Darby canine kidney cells. , 2001, Molecular biology of the cell.

[38]  D. Vestweber,et al.  The cell polarity protein ASIP/PAR‐3 directly associates with junctional adhesion molecule (JAM) , 2001, The EMBO journal.

[39]  L. Holmgren,et al.  Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation. , 2001, The Journal of cell biology.

[40]  T. Pawson,et al.  A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity , 2000, Nature Cell Biology.

[41]  Haigen Huang,et al.  Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish , 2000, Nature Cell Biology.

[42]  G. Joberty,et al.  The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 , 2000, Nature Cell Biology.

[43]  G. James,et al.  MAGI-1 interacts with beta-catenin and is associated with cell-cell adhesion structures. , 2000, Biochemical and biophysical research communications.

[44]  I. Mellman,et al.  Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells , 1999, Nature Cell Biology.

[45]  Douglas I. Johnson.  Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity , 1999, Microbiology and Molecular Biology Reviews.

[46]  W. Nelson,et al.  Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases , 1998, The Journal of cell biology.

[47]  M. Aigle,et al.  Protein-protein interaction between the RVS161 and RVS167 gene products of Saccharomyces cerevisiae. , 1997, Biochimica et biophysica acta.

[48]  C. Nobes,et al.  Regulation and function of the Rho subfamily of small GTPases. , 1994, Current opinion in genetics & development.

[49]  U. Tepass,et al.  Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster. , 1993, Developmental biology.

[50]  J. Pringle,et al.  Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity , 1990, The Journal of cell biology.

[51]  C. Yeaman,et al.  New perspectives on mechanisms involved in generating epithelial cell polarity. , 1999, Physiological reviews.