Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases
暂无分享,去创建一个
L. Klimek | T. Jakob | T. Kündig | M. Bachmann | C. Schmidt‐Weber | M. Kramer | Mona O. Mohsen | E. Jensen‐Jarolim | S. Guethoff | O. Palomares
[1] M. Vogel,et al. Allergens displayed on virus‐like particles are highly immunogenic but fail to activate human mast cells , 2018, Allergy.
[2] R. Janssen,et al. Immunogenicity of a two-dose investigational hepatitis B vaccine, HBsAg-1018, using a toll-like receptor 9 agonist adjuvant compared with a licensed hepatitis B vaccine in adults. , 2018, Vaccine.
[3] D. Stuart,et al. Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy , 2017, npj Vaccines.
[4] M. Bachmann,et al. Major findings and recent advances in virus-like particle (VLP)-based vaccines. , 2017, Seminars in immunology.
[5] M. Bachmann,et al. Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax , 2017, Vaccines.
[6] T. Kündig,et al. Allergen‐specific immunotherapy: is it vaccination against toxins after all? , 2017, Allergy.
[7] I. Pali-Schöll,et al. The concept of allergen-associated molecular patterns (AAMP). , 2016, Current opinion in immunology.
[8] C. Stremnitzer,et al. Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform , 2016, Oncoimmunology.
[9] C. Stremnitzer,et al. Adeno-associated virus-like particles as new carriers for B-cell vaccines: testing immunogenicity and safety in BALB/c mice. , 2014, Viral immunology.
[10] L. Klimek,et al. Immunotherapy of Allergic Rhinitis: New Therapeutic Opportunities with Virus-like Particles Filled with Cpg Motifs , 2013, American journal of rhinology & allergy.
[11] W. Renner,et al. The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma. , 2013, The Journal of allergy and clinical immunology.
[12] R. Schlosser,et al. Subcutaneous and sublingual immunotherapy for allergic rhinitis: What is the evidence? , 2012, American journal of rhinology & allergy.
[13] O. Pfaar,et al. Assessment of clinical efficacy of CYT003‐QbG10 in patients with allergic rhinoconjunctivitis: a phase IIb study , 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[14] T. Kündig,et al. Epicutaneous allergen administration: is this the future of allergen‐specific immunotherapy? , 2011, Allergy.
[15] Martin F. Bachmann,et al. Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns , 2010, Nature Reviews Immunology.
[16] R. Dummer,et al. Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients , 2010, Journal of immunotherapy.
[17] Sudhir Gupta,et al. TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors , 2010, Journal of Clinical Immunology.
[18] H. Riechelmann,et al. Efficacy and Safety of a Glutaraldehyde-Modified House Dust Mite Extract in Allergic Rhinitis , 2010, American journal of rhinology & allergy.
[19] M. Blaiss. Allergic rhinitis: Direct and indirect costs. , 2010, Allergy and asthma proceedings.
[20] J. Farrar,et al. Cutting Edge: Type I IFN Reverses Human Th2 Commitment and Stability by Suppressing GATA3 , 2010, The Journal of Immunology.
[21] J. Yewdell. Designing CD8+ T cell vaccines: it's not rocket science (yet). , 2010, Current opinion in immunology.
[22] Hyunjin Shin,et al. TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients1 , 2009, The Journal of Immunology.
[23] M. Bachmann,et al. Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy , 2009, The Journal of experimental medicine.
[24] J. M. Grant,et al. Viral Sequestration of Antigen Subverts Cross Presentation to CD8+ T Cells , 2009, PLoS pathogens.
[25] T. Kündig,et al. Use of A‐type CpG oligodeoxynucleotides as an adjuvant in allergen‐specific immunotherapy in humans: a phase I/IIa clinical trial , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[26] A. Krieg,et al. Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. , 2009, Advanced drug delivery reviews.
[27] J. Rolland,et al. Allergen-related approaches to immunotherapy. , 2009, Pharmacology & therapeutics.
[28] B. Wüthrich,et al. Intralymphatic allergen administration renders specific immunotherapy faster and safer: A randomized controlled trial , 2008, Proceedings of the National Academy of Sciences.
[29] K. Blaser. Immunologische Grundlagen der allergenspezifischen Immuntherapie , 2008, HNO.
[30] W. Sterry,et al. Phase 1 Evaluation of Intralesionally Injected TLR9-agonist PF-3512676 in Patients With Basal Cell Carcinoma or Metastatic Melanoma , 2008, Journal of immunotherapy.
[31] Katrin Schwarz,et al. Nanoparticles target distinct dendritic cell populations according to their size , 2008, European journal of immunology.
[32] Martin F. Bachmann,et al. The coming of age of virus-like particle vaccines , 2008, Biological chemistry.
[33] G. Viegi,et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 * , 2008, Allergy.
[34] G. Weiner,et al. CpG oligodeoxynucleotides as immunotherapy in cancer. , 2008, Update on cancer therapeutics.
[35] S. Kippenberger,et al. Clinical application of CpG-, non-CpG-, and antisense oligodeoxynucleotides as immunomodulators. , 2008, Current opinion in molecular therapeutics.
[36] B. Lambrecht,et al. GATA3-Driven Th2 Responses Inhibit TGF-β1–Induced FOXP3 Expression and the Formation of Regulatory T Cells , 2007, PLoS biology.
[37] B. Bacon,et al. Phase 1B, randomized, double‐blind, dose‐escalation trial of CPG 10101 in patients with chronic hepatitis C virus , 2007, Hepatology.
[38] P. Kuna,et al. Decreased markers of atopy in children with presumed early exposure to allergens, unhygienic conditions, and infections. , 2007, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[39] A. Krieg. Antiinfective applications of toll-like receptor 9 agonists. , 2007, Proceedings of the American Thoracic Society.
[40] J. Kline. Eat dirt: CpG DNA and immunomodulation of asthma. , 2007, Proceedings of the American Thoracic Society.
[41] Henry C Kitchener,et al. Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial , 2007, The Lancet.
[42] B. Chackerian,et al. Virus-like particles: flexible platforms for vaccine development , 2007, Expert review of vaccines.
[43] Daron G Ferris,et al. Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases. , 2007, The New England journal of medicine.
[44] R. Coffman,et al. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists , 2007, Nature Medicine.
[45] A. Krieg. Development of TLR9 agonists for cancer therapy. , 2007, The Journal of clinical investigation.
[46] C. Akdis,et al. Mechanisms of allergen-specific immunotherapy. , 2007, The Journal of allergy and clinical immunology.
[47] M. Larché,et al. Update on the current status of peptide immunotherapy. , 2007, The Journal of allergy and clinical immunology.
[48] R. Valenta,et al. Recombinant allergens for immunotherapy. , 2007, The Journal of allergy and clinical immunology.
[49] M. Benson,et al. Expression of Toll-like Receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis , 2007, Respiratory research.
[50] M. Kapsenberg,et al. Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. , 2007, The Journal of investigative dermatology.
[51] A. Sheikh,et al. Allergen injection immunotherapy for seasonal allergic rhinitis. , 2007, The Cochrane database of systematic reviews.
[52] X. Qin,et al. Plasmacytoid dendritic cells prime IL-10–producing T regulatory cells by inducible costimulator ligand , 2007, The Journal of experimental medicine.
[53] B. Wüthrich,et al. Immunotherapeutic targeting of allergic disease. , 2006, Inflammation & allergy drug targets.
[54] R. Coffman,et al. Immunotherapy With a Ragweed-Toll-Like Receptor 9 Agonist Vaccine for Allergic Rhinitis , 2007, Pediatrics.
[55] C. Akdis,et al. Mechanisms of allergen specific immunotherapy – T‐cell tolerance and more , 2006, Allergy.
[56] T. Kündig,et al. Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults. , 2006, The Journal of allergy and clinical immunology.
[57] A. Krieg,et al. Therapeutic potential of Toll-like receptor 9 activation , 2006, Nature Reviews Drug Discovery.
[58] H. Fiebig,et al. Strategies for recombinant allergen vaccines and fruitful results from first clinical studies. , 2006, Immunology and allergy clinics of North America.
[59] Sai T Reddy,et al. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[60] H. Malling,et al. Side‐effects of allergen‐specific immunotherapy. A prospective multi‐centre study , 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[61] R. Coffman,et al. Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction , 2005, The Journal of experimental medicine.
[62] Cezmi A Akdis,et al. T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases. , 2005, The Journal of allergy and clinical immunology.
[63] B. Baban,et al. Cutting Edge: CpG Oligonucleotides Induce Splenic CD19+ Dendritic Cells to Acquire Potent Indoleamine 2,3-Dioxygenase-Dependent T Cell Regulatory Functions via IFN Type 1 Signaling1 , 2005, The Journal of Immunology.
[64] S. Plotkin,et al. Vaccines: past, present and future , 2005, Nature Medicine.
[65] Jeffrey B Ulmer,et al. Targeting the innate immune response with improved vaccine adjuvants , 2005, Nature Medicine.
[66] D. Speiser,et al. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. , 2005, The Journal of clinical investigation.
[67] J. Friedberg,et al. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity. , 2005, Blood.
[68] G. Trinchieri,et al. Plasmacytoid dendritic cells in immunity , 2004, Nature Immunology.
[69] S. Durham,et al. Prevalence and rate of diagnosis of allergic rhinitis in Europe , 2004, European Respiratory Journal.
[70] C. Cooper,et al. CPG 7909, an Immunostimulatory TLR9 Agonist Oligodeoxynucleotide, as Adjuvant to Engerix-B® HBV Vaccine in Healthy Adults: A Double-Blind Phase I/II Study , 2004, Journal of Clinical Immunology.
[71] Y. Li,et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. , 2004, Vaccine.
[72] H. Matsue,et al. TLR3-, TLR7-, and TLR9-Mediated Production of Proinflammatory Cytokines and Chemokines from Murine Connective Tissue Type Skin-Derived Mast Cells but Not from Bone Marrow-Derived Mast Cells 1 , 2004, The Journal of Immunology.
[73] C. L. Hardy,et al. Blocking antibodies in allergen immunotherapy: the Yin and Yang , 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[74] S. Durham,et al. Grass Pollen Immunotherapy Induces Mucosal and Peripheral IL-10 Responses and Blocking IgG Activity1 , 2004, The Journal of Immunology.
[75] S. Durham,et al. Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy. , 2003, The Journal of allergy and clinical immunology.
[76] S. Halperin,et al. A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. , 2003, Vaccine.
[77] C. Bode,et al. CpG DNA as a vaccine adjuvant , 2003, Expert review of vaccines.
[78] J. Bousquet,et al. Allergic Rhinitis and its Impact on Asthma (ARIA) , 2003 .
[79] G. Lipowsky,et al. Regulation of IgG antibody responses by epitope density and CD21‐mediated costimulation , 2002, European journal of immunology.
[80] D. Nowak,et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. , 2002, The New England journal of medicine.
[81] P. Eng,et al. Long‐term efficacy of preseasonal grass pollen immunotherapy in children , 2002, Allergy.
[82] M. Khan,et al. Targeting to macrophages: role of physicochemical properties of particulate carriers--liposomes and microspheres--on the phagocytosis by macrophages. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[83] Erkka Valovirta,et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). , 2002, The Journal of allergy and clinical immunology.
[84] Dennis Nowak,et al. Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey , 2001, The Lancet.
[85] N. York,et al. Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six‐year follow‐up study. , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[86] M. Swartz,et al. The physiology of the lymphatic system. , 2001, Advanced drug delivery reviews.
[87] J. Castro‐Rodriguez,et al. Siblings, day-care attendance, and the risk of asthma and wheezing during childhood. , 2000, The New England journal of medicine.
[88] W Chiu,et al. Structures of virus and virus-like particles. , 2000, Current opinion in structural biology.
[89] I. Frazer,et al. HPV6b virus like particles are potent immunogens without adjuvant in man. , 2000, Vaccine.
[90] S. Durham,et al. Allergen immunotherapy: does it work and, if so, how and for how long? , 2000, Thorax.
[91] J Bousquet,et al. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. , 1998, The Journal of allergy and clinical immunology.
[92] D. P. Strachan,et al. Hay fever, hygiene, and household size. , 1989, BMJ.
[93] C. Schmidt‐Weber. Anti-IL-4 as a new strategy in allergy. , 2012, Chemical immunology and allergy.
[94] L. Capelle,et al. Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma. , 2006, Neuro-oncology.
[95] R. Steinman,et al. The innate functions of dendritic cells in peripheral lymphoid tissues. , 2005, Advances in experimental medicine and biology.